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X-WR-CALDESC:Events for Northeastern University College of Engineering
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DTSTART;VALUE=DATE:20201015
DTEND;VALUE=DATE:20201231
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CREATED:20201015T142444Z
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SUMMARY:Meet Your Graduate Student Ambassadors!
DESCRIPTION:Meet your Student Ambassadors! Prospective and Admitted Graduate Students are invited to meet their Student Ambassador via Unibuddy.
URL:https://coe.northeastern.edu/event/meet-your-graduate-student-ambassadors/
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201028T120000
DTEND;TZID=America/New_York:20201028T123000
DTSTAMP:20260526T225337
CREATED:20201026T135220Z
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SUMMARY:Engineering targeted therapeutics for breast cancer
DESCRIPTION:ChE Seminar Series Presents:   \nDebra Auguste\, Ph.D.\nProfessor\, Department of Chemical Engineering\nNortheastern University\, Boston\, MA \n“Engineering targeted therapeutics for breast cancer” \nAbstract: Cells sense changes in their environment and respond by altering their gene expression.  My lab investigates how cells manipulate membrane proteins\, which has profound effects on disease progression. Cells orchestrate the density of proteins and lipids to govern adhesion and migration. From this knowledge\, one can engineer drug delivery vehicles that complement the molecular patterns observed on cells to achieve strong\, cooperative binding. I have employed these strategies in a model system of endothelial inflammation and in breast cancer metastasis. My lab has identified a new target and biomarker for triple negative breast cancer\, examined the role of ligand/receptor cell adhesion by atomic force microscopy\, and synthesized targeted drug delivery vehicles that demonstrate that nanoparticle ligand surface density alters gene expression. \nBiography: Debra Auguste\, PhD is a Professor of Chemical Engineering at Northeastern University. She received her S.B. in Chemical Engineering from MIT in 1999 and her Ph.D. in Chemical Engineering from Princeton University in 2005. She was trained as a Post-Doctoral Associate at MIT under Institute Professor Robert Langer.  Her interests include drug and gene delivery\, targeted drug delivery\, stimuli sensitive materials. Dr. Auguste is the principal investigator on grants from the National Institute of Health (NIH)\, Office of Naval Research (ONR)\, Defense Advanced Research Projects Agency (DARPA)\, National Science Foundation (NSF)\, and the Juvenile Diabetes Research Foundation (JDRF). She is a recipient of various awards including: the Presidential Early Career in Science and Engineering- 2013\, the NIH Innovator-2012\, NSF CAREER Award-2011\, and the DARPA Young Faculty Award-2009. Dr. Auguste was elected as a Fellow of the Biomedical Engineering Society (2018) and the American Institute of Medical and Biological Engineering (2020). Dr. Auguste sits on the Scientific Advisory Board of PATHS UP at Texas A&M University and Shriners Hospital for Children in Boston. Dr. Auguste is on the Board of Directors for BMES. Dr. Auguste is co-chair of the BMES national meeting (2020). \nPlease email Alyssa Ramsey at a.ramsey@northeastern.edu for the link to the seminar.
URL:https://coe.northeastern.edu/event/engineering-targeted-therapeutics-for-breast-cancer/
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DTSTART;TZID=America/New_York:20201028T120000
DTEND;TZID=America/New_York:20201028T130000
DTSTAMP:20260526T225337
CREATED:20201014T185847Z
LAST-MODIFIED:20201014T185847Z
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SUMMARY:BioE Seminar Series Presents: Blanka Sharma
DESCRIPTION:Blanka Sharma\, Ph.D. \nAssociate Professor\, Department of Biomedical Engineering\, University of Florida\, Gainesville\, FL  \n“Engineering Biomaterials to Study and Modulate Inflammatory Mechanisms During Tissue Injury and Tumor Progression” \nABSTRACT:   \nExciting advances have been made in the discovery of therapeutic molecules and cells to more effectively treat numerous devastating medical conditions. However\, their successful application in patients is curtailed by significant challenges in effectively delivering these therapeutics where an injury or disease is localized. Dr. Sharma’s research program aims to address these challenges by engineering biomaterials capable of presenting biological signals in a site specific manner within the body. The first part of this talk will focus on drug delivery challenges for the treatment of osteoarthritis. Dr. Sharma will describe her group’s work to overcome barriers to effective drug delivery within joint\, by exploiting specific nanoparticle-extracellular matrix interactions to improve tissue targeting and retention of therapeutic molecules within OA joints. Dr. Sharma will highlight a nanoparticle system that was engineered to target oxidative stress pathways in damaged articular cartilage via scavenging of reactive oxygen species\, resulting in the protection of cartilage viability and tissue structure. The second part of this talk will focus on cell delivery challenges in cancer immunotherapies\, whereby solid tumors create a local immunosuppressive microenvironment that diminish immune cell surveillance and facilitate tumor progression. Dr. Sharma’s laboratory is applying biomaterials to understand how the tumor microenvironment impacts the homing and activation of natural killer (NK) cells\, and developing RNA delivery strategies to harness their cancer killing functions. Mitigating dysfunctional inflammatory mechanisms is key to both tissue remodeling and cancer progression\, and Dr. Sharma’s group works at the intersection of these fields. \nBIOGRAPHY: \nDr. Sharma is an Associate Professor of Biomedical Engineering at the University of Florida. Her research investigates fundamental biomaterial-cell interactions to develop targeted drug and cell delivery systems for applications ranging from tissue repair to cancer therapy. Dr. Blanka Sharma received her undergraduate degree in Chemical Engineering from the University of Waterloo (Waterloo\, Ontario\, Canada)\, her Ph.D. from Johns Hopkins University (Baltimore\, MD) in the Department of Biomedical Engineering\, and her postdoctoral training at the Cleveland Clinic (Cleveland\, OH). Dr. Sharma served as Director of Research for Cartilix Inc. from 2005-2009\, a start-up company based on her doctoral research\, where she worked towards clinical translation of a hydrogel technology for cartilage repair in the knee. After starting her faculty position in 2014 at the University of Florida\, Dr. Sharma was featured by the American Society for Engineering Education as one of “20 Under 40” Outstanding Junior Faculty in the U.S.  More recently\, Dr. Sharma received the National Science Foundation Faculty Early Career Development Program (CAREER) award (2019). In recognition of her teaching\, mentorship\, and research\, Dr. Sharma received the Pramod P. Khargonekar Junior Faculty Award for Excellence in 2020 from the UF College of Engineering. \nIf interested in attending\, please email Elizabeth Chesley at e.chesley@northeastern.edu for the Zoom link.
URL:https://coe.northeastern.edu/event/bioe-seminar-series-presents-blanka-sharma/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201028T123000
DTEND;TZID=America/New_York:20201028T130000
DTSTAMP:20260526T225337
CREATED:20201026T135612Z
LAST-MODIFIED:20201026T135612Z
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SUMMARY:ChE Seminar Series Presents: Sara Hashmi
DESCRIPTION:ChE Seminar Series Presents:\n \nSara Hashmi\, Ph.D.\nAssistant Professor\, Department of Chemical Engineering\nNortheastern University\, Boston\, MA \nAbstract/Bio: Information not available at this time \nPlease email Alyssa Ramsey at a.ramsey@northeastern.edu for the link to the seminar.
URL:https://coe.northeastern.edu/event/che-seminar-series-presents-sara-hashmi/
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