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X-WR-CALDESC:Events for Northeastern University College of Engineering
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DTSTART;VALUE=DATE:20201015
DTEND;VALUE=DATE:20201231
DTSTAMP:20260603T011544
CREATED:20201015T142444Z
LAST-MODIFIED:20201015T142444Z
UID:22804-1602720000-1609372799@coe.northeastern.edu
SUMMARY:Meet Your Graduate Student Ambassadors!
DESCRIPTION:Meet your Student Ambassadors! Prospective and Admitted Graduate Students are invited to meet their Student Ambassador via Unibuddy.
URL:https://coe.northeastern.edu/event/meet-your-graduate-student-ambassadors/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201104T120000
DTEND;TZID=America/New_York:20201104T123000
DTSTAMP:20260603T011544
CREATED:20201030T205522Z
LAST-MODIFIED:20201030T205622Z
UID:22960-1604491200-1604493000@coe.northeastern.edu
SUMMARY:Engineered Models of the Enteric-Gut-Axis
DESCRIPTION:ChE Seminar Series Presents:   \nAbigail N. Koppes\, Ph.D.\nAssistant Professor\, Department of Chemical Engineering\nAffiliate in Biology and Bioengineering \n“Engineered Models of the Enteric-Gut-Axis” \nAbstract: The gut-brain-axis is a complex bi-directional communication pathway between the gastrointestinal tract\, the enteric nervous system (ENS)\, and the central nervous system (CNS) that is implicated in not only gastrointestinal function but also cognitive tasks like memory and decision making. Gastrointestinal flora has also been implicated in alterations of brain function and behavior\, however\, mechanisms behind the gut-to-brain communication remain poorly understood. To investigate the mechanisms for epithelial/neural interactions in the gastrointestinal tract and understand the impact of alterations in neural activity in response to intestinal contents\, we are developing in vitro humanized culture models of the enteric-gut axis. These platforms\, termed “Microphysiological Systems or Organ-Chips” have generated interest from academia and industry as these physiological models may augment drug and basic biological discoveries. However\, the lack of rapid\, scalable\, and facile manufacturing techniques may limit the widespread use of organs-on-chips. Here I will discuss a novel laser-cut and assembly-based fabrication method for simple\, and cost-effective thermoplastic organ-chips. It has also been proposed that seeding patient-derived cells will enable personalized medicine\, but current intestine-on-a-chip models often utilize immortalized cells and rarely include support cells such as enteric neurons. Finally\, I will discuss the culture and differentiation of a primary\, human epithelial monolayer from patient-derived intestinal organoids for on-chip studies that recapitulate the heterogeneous gut population\, and the impact of trophic cross-talk between the epithelium and enteric populations in static models. \nBiography: Dr. Abigail Koppes joined the department of Chemical Engineering at Northeastern University in 2014 where her group\, the Advanced Biomaterials for Neuroengineering Laboratory (ABNEL)\, harnesses biochemical engineering methods to address challenges in nervous system disorders and dysfunction. She was the recipient of the NIH R21 Trailblazer in 2017\, is a co-investigator on a 2019 AHA Innovative Project Award and is a co-investigator on a 2016 NIH Biomedical Research Partnership R01 between Northeastern\, MIT\, and Boston Children’s Hospital. She received the 2020 BMES Rita Shaffer Young Investigator and CMBE Young Innovator Award in 2020. She received her Ph.D. in Biomedical Engineering from Rensselaer Polytechnic Institute (RPI) in Troy\, New York in 2013. Her doctoral research with Dr. Deanna Thompson focused on using electrical stimulation to manipulate neural and supportive glial cell behavior for improved repair following peripheral nervous system injuries. In 2013\, Dr. Koppes joined the Advanced Drug Delivery Research Laboratory with Dr. Rebecca Carrier as the Northeastern University NSF ADVANCE Future Faculty Fellow and held a joint appointment at Schepen’s Eye Research Institute and Harvard Medical School with Dr. Michael Young and as a visiting scientist in Dr. Douglas Lauffenburger’s Molecular Cell Bioengineering group at MIT. At Northeastern Dr. Koppes enjoys teaching Design 1 Lab (Unit Operations Transport I) for undergraduate engineers and Design of Experiments and Ethical Research for graduate students\, where she is a member of the DEI and graduate committees\, as well as has mentored over 40 undergraduates in the laboratory. She also currently serves on the BMES Diversity Committee. \nPlease email Alyssa Ramsey at a.ramsey@northeastern.edu for the link to the seminar.
URL:https://coe.northeastern.edu/event/engineered-models-of-the-enteric-gut-axis/
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DTSTART;TZID=America/New_York:20201104T120000
DTEND;TZID=America/New_York:20201104T130000
DTSTAMP:20260603T011544
CREATED:20200930T184121Z
LAST-MODIFIED:20200930T184121Z
UID:22468-1604491200-1604494800@coe.northeastern.edu
SUMMARY:BioE Seminar Series Presents: Leyla Esfandiari
DESCRIPTION:Leyla Esfandiari\, Ph.D. \nAssistant professor\, Department of Electrical Engineering and Biomedical Engineering\, University of Cincinnati\, Cincinnati OH \n“Electrokinetically Driven Micro-pores for Minimally-Invasive Cancer Diagnosis” \nAbstract:  \nEarly detection of cancer is essential for improved long-term survival of patients. Traditionally\, invasive and costly procedures\, such as surgical tissue biopsies have been used for cancer screening. However\, over the past few decades\, advancements in microfluidics and lab-on-a-chip approaches have been made to develop minimally invasive and miniaturized platforms to detect the circulating cancer biomarkers from biofluids. Among circulating biomarkers\, small extracellular vesicles (exosomes)\, have drawn a great deal of attention due to their high abundance in all biofluids and their enriched and highly stable gene regulatory content including micro-RNAs. Tumor-derived exosomes have also shown potential for early diagnosis and prognosis of cancer in difficult to access tumor sites. However\, because of the complex nature of biofluids and the heterogeneous physicochemical properties of exosomes\, their accurate isolation and characterization raises significant challenges in clinical settings. To address these challenges\, we have developed a simple\, yet powerful electrokinetically driven micro-pore device capable of rapid and label-free purification of exosomes from biofluids by applying a significantly low electric field. The device is also tailored with an impedance measurement module to further characterize exosomes based on their unique dielectric properties. We have further used the micro-pores for rapid detection of sequence-specific circulating micro-RNAs with high sensitivity and accuracy.  \nBIOGRAPHY: \nDr. Leyla Esfandiari is a tenure-track assistant professor with dual appointment in the departments of Electrical Engineering and Biomedical Engineering at University of Cincinnati (UC). At UC\, she is the principal investigator of the Integrative BioSensing Laboratory (IBL) with the main focus on development of nano/micro-scaled bioanalytical tools\, organic bioelectronics\, and microfluidics for medical and environmental applications. She has been the member of Cincinnati Cancer Center and the Center for Stem Cell and Organoid Medicine (CuSTOM) at Cincinnati Children’s Hospital. Her research has been supported by the National Institute of Health/ National Cancer Institute\, National Science Foundation\, Department of Transportation (DOT) and Office of Research at UC.  \nDr. Esfandiari completed her doctoral degree in bioengineering from University of California Los Angeles (UCLA); and earned her MSc in biomedical engineering from University of California Irvine. While at UCLA\, she conducted research at the California Nano-System Institution (CNSI)\, the College of Medicine and the College of Engineering and Applied Sciences. Besides academic training\, she has had three years of experience in industry.  \nDr. Esfandiari has won numerous awards including UC College of Engineering and Applied Science Distinguished Research Award\, the William E. Restemeyer Teaching Excellence Award\, UC Faculty Development Award\, UCLA Unrestricted Fellowship\, UC Irvine Kleist Fellowship\, NSF Fellowship\, and Boeing Scholarship.   \nIf interested\, please email Elizabeth Chesley at e.chesley@northeastern.edu for the seminar link.
URL:https://coe.northeastern.edu/event/bioe-seminar-series-presents-leyla-esfandiari/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
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DTSTART;TZID=America/New_York:20201104T123000
DTEND;TZID=America/New_York:20201104T130000
DTSTAMP:20260603T011544
CREATED:20201030T205754Z
LAST-MODIFIED:20201030T205754Z
UID:22962-1604493000-1604494800@coe.northeastern.edu
SUMMARY:Magic or Magnetics? Novel Materials for Energy Transfer
DESCRIPTION:ChE Seminar Series Presents:  \nLaura H. Lewis\, Ph.D.\nDistinguished University and Cabot Professor\,  Chemical Engineering\nDistinguished University and Cabot Professor\,  Mechanical and Industrial Engineering \n“Magic or Magnetics? Novel Materials for Energy Transfer” \nAbstract: Magnetic materials permit the wireless interconversion of electrical\, mechanical and\, increasingly\, thermal energies to benefit an enormous breadth of technologies including sustainable energy\, e-mobility\, data storage and biomedicine. Magnetic performance may be controlled through engineering at the atomic\, nanoscopic and microstructural levels\, providing a vast arena for realization of new types of magnetic materials. This presentation provides a brief overview of selected research activities\, with focus on recent progress to realize a new material\, tetrataenite\, that holds promise as a new advanced permanent magnet free of critical\, geopolitically constrained elements. \nBiography: Laura H. Lewis is a Distinguished University and Cabot Professor of Chemical Engineering and Profes¬sor of Mechanical and Industrial Engineering at Northeastern University in Boston\, MA\, U.S.A. Prior to her faculty position at Northeastern University\, she was a research group leader and Associate Department Chair in the Nanoscience Department of Brookhaven National Laboratory (BNL)\, a U.S. Department of Energy Laboratory devoted to research in the physical\, biomedical\, and environmental sciences\, as well as in energy technologies. Concurrently\, she was the Deputy Director of the BNL Center for Functional Nanomaterials\, a DOE national user facility to provide researchers with state-of-the-art capabilities to fabricate and study nanoscale materials. Laura received her Ph.D. in Materials Science and Engineering from the University of Texas at Austin; she earned a M.S. degree in Electronic Materials from M.I.T. and a B.S. degree in Physics and Earth Sciences from the University of California at San Diego. \nLaura’s research focuses on investigating the materials factors at the atomic level that provide functionality to magnetic materials\, with a specialization in sustainable elements and rare earths. She has authored over 200 peer-reviewed publications and delivered over 100 invited presentations at national and international venues. She has participated on a number of advisory panels\, most recently as am Advisory Board Member of the Critical Materials Institute\, A DOE Energy Innovation Hub\, the IEEE Magnetics Society AdCom and International Advisory Committee of the Joint European Magnetics Symposia. She has been appointed as a member of the U.S. Technical Advisory Group to the ISO/TC 298 Standard for Rare Earth that will determine the U.S. position on standardization in the field of rare earth mining\, concentration\, extraction\, separation and conversion to useful rare earth compounds/materials which are key inputs to manufacturing and technologies. \nLaura is a Senior Member of the IEEE and served as Conference Editor of the IEEE Transactions on Magnetics (2008 – 2018) and Chair of the IEEE Magnetics Society Technical Committee (2017 – 2019). She is a Fellow of the American Physical Society\, a Fulbright Fellow as well as a member of the Materials Research Society\, the American Chemical Society and the American Society for Engineering Education. \nPlease email Alyssa Ramsey at a.ramsey@northeastern.edu for the link to the seminar.
URL:https://coe.northeastern.edu/event/magic-or-magnetics-novel-materials-for-energy-transfer/
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