BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Northeastern University College of Engineering - ECPv6.15.20//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:Northeastern University College of Engineering
X-ORIGINAL-URL:https://coe.northeastern.edu
X-WR-CALDESC:Events for Northeastern University College of Engineering
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:America/New_York
BEGIN:DAYLIGHT
TZOFFSETFROM:-0500
TZOFFSETTO:-0400
TZNAME:EDT
DTSTART:20250309T070000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0400
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:20251102T060000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0500
TZOFFSETTO:-0400
TZNAME:EDT
DTSTART:20260308T070000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0400
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:20261101T060000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0500
TZOFFSETTO:-0400
TZNAME:EDT
DTSTART:20270314T070000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0400
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:20271107T060000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;VALUE=DATE:20260324
DTEND;VALUE=DATE:20260325
DTSTAMP:20260503T134913
CREATED:20260302T145402Z
LAST-MODIFIED:20260318T203311Z
UID:55653-1774310400-1774396799@coe.northeastern.edu
SUMMARY:University of South Carolina Career and Internship Fair
DESCRIPTION:Join COE Graduate Admissions at the 2026 University of South Carolina Career and Internship Fair in Columbia\, South Carolina! Ask your questions about our graduate engineering programs across the U.S. and Canada during the fair on March 25th. We look forward to meeting you there!
URL:https://coe.northeastern.edu/event/university-of-south-carolina-career-and-internship-fair/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20260324T090000
DTEND;TZID=America/New_York:20260324T100000
DTSTAMP:20260503T134913
CREATED:20260227T160103Z
LAST-MODIFIED:20260227T160103Z
UID:55573-1774342800-1774346400@coe.northeastern.edu
SUMMARY:Deep Dive into Chemical Engineering Research Webinar
DESCRIPTION:As you continue exploring your graduate school options\, we invite you to join a special webinar highlighting the exciting research taking place within our Chemical Engineering Department. Our faculty’s work spans several key areas—Biomolecular & Biomedical Systems\, Complex & Computational Systems\, Energy & Sustainability\, Engineering Education & Pedagogy\, and Materials & Nanotechnology. Across these domains\, Northeastern is advancing the integration of biological and physical systems\, creating innovative opportunities for interdisciplinary discovery. \nDuring this session\, you’ll hear an overview of each research area and have the opportunity to ask faculty members questions about their work. Presenters will include Dr. Eno Ebong\, Dr. Adam Ekenseair\, and additional members of our research community.
URL:https://coe.northeastern.edu/event/deep-dive-into-chemical-engineering-research-webinar/
LOCATION:Virtual
ORGANIZER;CN="Graduate School of Engineering":MAILTO:coe-gradadmissions@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20260324T100000
DTEND;TZID=America/New_York:20260324T110000
DTSTAMP:20260503T134913
CREATED:20260127T153114Z
LAST-MODIFIED:20260318T203130Z
UID:55151-1774346400-1774350000@coe.northeastern.edu
SUMMARY:Crafting Data Visuals to Tell a Scientific Story: CommLab Drop-In Hours
DESCRIPTION:Looking to illustrate your data? Join our Data Visualization Drop-In sessions Tuesdays from 10-11am on Zoom to discuss strategies or receive feedback on your data visualization process.
URL:https://coe.northeastern.edu/event/crafting-data-visuals-to-tell-a-scientific-story-commlab-drop-in-hours/2026-03-24/
LOCATION:https://northeastern.zoom.us/j/99770601100?pwd=mbD3JHc7u0fjb558MDmqIHoSNBMrsS.1
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20260324T110000
DTEND;TZID=America/New_York:20260324T120000
DTSTAMP:20260503T134913
CREATED:20260126T152754Z
LAST-MODIFIED:20260318T203211Z
UID:55109-1774350000-1774353600@coe.northeastern.edu
SUMMARY:CV/LinkedIn/Resume CommLab Drop-In Hours
DESCRIPTION:Graduate students\, do you need to increase your on-line presence or update your CV or Resume?  Join the CommLab’s LinkedIn\, CV\, and Resume drop-in hours any Tuesday from 11 am to 12 pm ET. This collaborative space offers valuable advice and peer feedback to enhance your online profile and professional presence. Join this drop-in workshop in person in room 334 CSC or through Zoom.
URL:https://coe.northeastern.edu/event/cv-linkedin-resume-commlab-drop-in-hours/2026-03-24/
LOCATION:https://northeastern.zoom.us/meeting/register/tJEof-quqzwiGNCi3nAuNVzIyX1jgXA03KYO
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20260324T150000
DTEND;TZID=America/New_York:20260324T160000
DTSTAMP:20260503T134913
CREATED:20260316T142439Z
LAST-MODIFIED:20260316T142439Z
UID:55816-1774364400-1774368000@coe.northeastern.edu
SUMMARY:ChE PhD Dissertation Defense: Victus Kordorwu
DESCRIPTION:Name:\nVictus Kordorwu \nTitle:\nUnderstanding the role of mucus in supersaturated drug delivery \nDate:\n03/24/2026 \nTime:\n03:00:00 PM \nCommittee Members:\nProf. Rebecca Carrier (Advisor)\nProf. Steve Lustig (Co-Advisor)\nProf. Mansoor Amiji\nSteven Castleberry\, PhD\nDennis Leung\, PhD \nLocation:\nCSC 333 \nAbstract:\nMany drugs entering clinical trials today are poorly water-soluble and rely on supersaturating formulations such as amorphous solid dispersions (ASD) to generate transient supersaturated states in the gastrointestinal tract to enhance the bioavailability. However\, correlating the rate and extent of drug precipitation observed in vitro to in vivo performance of supersaturating formulations has proven to be very difficult with limited success in establishing predictive relationships. This difficulty suggests that some aspects of the relevant in vivo environment which impact the performance of supersaturating formulations is possibly overlooked by current biorelevant dissolution methods used to evaluate the in vivo performance of these formulations. Mucus and mucins are key components of the in vivo environment and can undergo numerous types of interactions with different molecules and solutes (e.g.\, drugs\, polymers\, additives). Yet\, many in vitro biorelevant dissolution testing methods used to evaluate the performance of metastable formulations do not incorporate mucins\, leading to potential discrepancies between in vitro and in vivo drug performance prediction. \nDetailed in this work are mechanistic\, thermodynamic\, and translational investigations into the role of intestinal mucin as an active modulator of drug supersaturation stability and formulation performance. Mucin is shown to mimic and impact the ability of ASD polymers to stabilize supersaturated drug solutions. Mucin-mediated supersaturation translated to increased drug absorption through transport studies using Caco-2/HT29-MTX-E12 co-culture. Importantly\, mucin is found to alter the apparent performance of classical polymeric precipitation inhibitors\, either synergistically enhancing or antagonistically diminishing polymer effectiveness depending on the drug system\, thereby reshaping excipient rankings under physiologically relevant conditions. \nThe thermodynamics of drug-mucin interactions were explored using isothermal titration calorimetry (ITC) and ATR-FTIR 2D dimensional correlation spectroscopy. Small molecule binding exhibits two-event association behavior and is predominantly enthalpy driven\, consistent with hydrogen bonding and conformational ordering within the mucin network. Spectroscopic analyses reveal coordinated perturbations across hydroxyl\, amide\, carboxylate\, hydrophobic\, and saccharide associated domains\, confirming heterogeneous interaction environments and diffusion coupled structural rearrangements. \nBuilding on these mechanistic understanding\, a thermo-statistical Gibbs energy framework is developed to quantitatively predict the rank ordering and impact of mucin and excipients on drug precipitation across diverse compounds. The framework employs Gibbs energy curvature\, described as the second derivative of the Gibbs energy with respect to composition\, as a predictive descriptor of resistance to concentration fluctuations. Extension of this framework to the hydrophobic macrocyclic peptide\, cyclosporine A\, demonstrates that mucin also stabilizes peptide supersaturation through distinct entropy driven interaction pathways involving solvent restructuring. Curvature based predictions correlate with experimental precipitation outcomes and enable rational comparison of mucin and polymeric excipients as stabilizing agents. Overall\, this work demonstrates that intestinal mucus is an active modulator of supersaturation\, precipitation risk\, and formulation performance across both small molecule and peptide systems. Thus\, biorelevant dissolution testing should include appropriate mucus activity to enhance the predictive assessment of drug precipitation risk in supersaturated drug delivery systems. \n\nVictus Kordorwu is currently a Ph.D. candidate in Chemical Engineering at Northeastern University in Boston\, Massachusetts\, where he will graduate in April 2026. His doctoral research focuses on understanding the role of mucus in supersaturated drug delivery to improve formulation performance prediction. Victus holds a Master’s degree in Chemical Engineering and Technology from Dalian University of Technology in China and a Bachelor’s degree in Petroleum Engineering from Kwame Nkrumah University of Science and Technology in Ghana. \nDuring his doctoral studies\, he completed a 6-months research internship at Takeda Pharmaceutical Company\, where he gained expertise in RNA-lipid nanoparticle and oral solid dosage formulation and process development. His research contributions have resulted in peer-reviewed publications and presentations at conferences including the AIChE Annual Meeting\, Controlled Release Society \, the American Chemical Society and the Society for Biomaterials. \nHis research interests span formulation and process development\, biomaterials and soft matter systems and the development of predictive tools for complex chemical and biological systems. He is particularly interested applying chemical engineering expertise to solve problems across pharmaceutical development\, biotechnology\, energy related materials\, and other complex chemical systems. In the short term\, he looks forward to working as chemical engineer and formulation scientist in the pharmaceutical industry to deepen his expertise in pharmaceutical development. Outside of academics\, Victus enjoys playing bass and publishing bass tutorials\, kayaking and swimming.
URL:https://coe.northeastern.edu/event/che-phd-dissertation-defense-victus-kordorwu/
LOCATION:333 CSC\, 360 Huntington Ave\, 333 CSC\, Boston\, MA\, 02115\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20260324T153000
DTEND;TZID=America/New_York:20260324T160000
DTSTAMP:20260503T134913
CREATED:20260319T140940Z
LAST-MODIFIED:20260319T140940Z
UID:55971-1774366200-1774368000@coe.northeastern.edu
SUMMARY:MIE Seminar: Distributionally Robust Learning – From Traditional to Deep and to Reinforcement Learning
DESCRIPTION:MIE Seminar Speaker: Dr. Ioannis Paschalidis\, Distinguished Professor of Engineering\, Founding Professor of Computing & Data Sciences\, and Director\, Hariri Institute for Computing and Computational Science & Engineering at Boston University. \nDr. Paschalidis will present a seminar titled: “Distributionally Robust Learning – From Traditional to Deep and to Reinforcement Learning.” This seminar presents a distributionally robust machine learning framework that addresses outliers and uncertainty by optimizing worst-case performance\, with applications ranging from medical decision-making and deep learning to safe reinforcement learning in robotics and autonomous systems. \nLocation: 011 Kariotis
URL:https://coe.northeastern.edu/event/mie-seminar-distributionally-robust-learning-from-traditional-to-deep-and-to-reinforcement-learning/
END:VEVENT
END:VCALENDAR