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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200930T120000
DTEND;TZID=America/New_York:20200930T123000
DTSTAMP:20260417T071912
CREATED:20200925T201242Z
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UID:22401-1601467200-1601469000@coe.northeastern.edu
SUMMARY:ChE Seminar: "Engineering the Production of Medicinal Natural Products from Plant Cell Cultures"
DESCRIPTION:ChE Seminar Series Presents:\n \nCarolyn W.T. Lee-Parsons\, Ph.D. \nAssociate Professor\, Chemical Engineering Department; Chemistry & Chemical Biology Department\, Northeastern University\, Boston\, MA \n“Engineering the Production of Medicinal Natural Products from Plant Cell Cultures” \nAbstract: \nMany plant-derived pharmaceuticals are currently supplied by extracting the plant material.  Due to the slow growth rates or low product concentrations in plants\, finding an alternative route for supplying these critical drugs is necessary.  The overall vision of this research is to enhance the production of critical plant-derived pharmaceutical compounds through genetically engineered plant cell cultures\, specifically using the production of terpenoid indole alkaloids (TIAs) from cultures of Catharanthus roseus as a model system.  The C. roseus plant produces several highly valued pharmaceuticals\, including the anti-cancer drugs vincristine and vinblastine.  The high cost and need for these pharmaceuticals motivate our research to better understand their biosynthesis and ultimately overproduce these compounds using C. roseus cultures.  In this talk\, I will present our research in exploring how TIA biosynthesis is regulated and how this knowledge leads to developing synthetic biology strategies for manipulating TIA production. \nBiography: \nCarolyn W.T. Lee-Parsons is an Associate Professor jointly appointed in the Departments of Chemical Engineering and of Chemistry and Chemical Biology at Northeastern University.  She earned her B.S. from the University of Kansas and her Ph.D. from Cornell University\, both in Chemical Engineering.  As an undergraduate\, she modeled reaction networks with Prof. Bala Subramaniam and investigated oil and gas recovery strategies at ARCO Oil and Gas. Growing up in the midst of wheat fields in Kansas\, she was always intrigued by plants and specifically medicines from plants.  As a doctoral student\, she investigated bioprocess strategies for increasing the production of medicines from plant cell cultures with Prof. Michael L. Shuler. \nHer current research area is in plant metabolic engineering and plant synthetic biology.  Her team of graduate and undergraduate students focus on understanding how plants regulate the production of specialized metabolites and on developing and applying tools for engineering the production of pharmaceutical compounds and biofuels from plant tissue cultures and microalgae cultures.  Carolyn seeks to engage majors across disciplines in understanding the fundamentals underlying life in living organisms and translating this understanding to developing solutions to society’s grand challenges.  She contributed to the revision of the widely used textbook for bioprocess engineering (Bioprocess Engineering:  Basic Concepts by M.L. Shuler\, F. Kargi\, and M. DeLisa).  For her teaching and research mentoring\, she was awarded the Martin Essigmann Outstanding Teaching Award and the University Excellence in Teaching Award at Northeastern University. \nPlease email Alyssa Ramsey at a.ramsey@northeastern.edu for the link to the seminar.
URL:https://coe.northeastern.edu/event/che-seminar-engineering-the-production-of-medicinal-natural-products-from-plant-cell-cultures/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200930T120000
DTEND;TZID=America/New_York:20200930T130000
DTSTAMP:20260417T071912
CREATED:20200909T173211Z
LAST-MODIFIED:20200909T173211Z
UID:22186-1601467200-1601470800@coe.northeastern.edu
SUMMARY:Effectively Navigating Challenging Conversations
DESCRIPTION:Would you like to gain respect\, achieve your goals\, and improve your professional relationships? What if this were possible by adjusting the way you communicate?   \nClick here to register for this virtual workshop! \nChallenging conversations are high-risk\, sometimes emotional discussions between individuals with differing opinions. This workshop will help graduate students recognize when challenging conversations are happening\, or need to happen\, and prepare them with strategies to navigate them productively. This includes being able to give both positive and negative feedback as well as receive it from colleagues and advisors\, in order to effectively meet personal\, academic\, and professional goals.  \nThis interactive workshop\, facilitated by COE CommLab Fellows\, will offer background on navigating challenging conversations\, and provide time for participants to work together in smaller groups to analyze\, assess\, process\, and practice frequently encountered scenarios. There will also be time for participants to discuss their own challenging conversations and make new strategies.   \nThis workshop is designed and facilitated by the COE CommLab and co-sponsored by the Office of the Graduate Obudsperson\, Employer Engagement and Career Design\, and the PhD Network.
URL:https://coe.northeastern.edu/event/effectively-navigating-challenging-conversations/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200930T120000
DTEND;TZID=America/New_York:20200930T130000
DTSTAMP:20260417T071912
CREATED:20200918T151310Z
LAST-MODIFIED:20200918T151310Z
UID:22322-1601467200-1601470800@coe.northeastern.edu
SUMMARY:BioE Seminar Series Presents: Tara Deans
DESCRIPTION:Tara Deans\, Ph.D. \nAssistant Professor\, Department of Biomedical Engineering\, University of Utah\, Salt Lake City\, Utah  \n“Using synthetic biology to engineer therapeutic devices” \nABSTRACT:   \nSynthetic biology has transformed how cells can be reprogrammed\, providing a means to reliably and predictably control cell behavior with the assembly of genetic parts into more complex gene circuits. Using these approaches\, we are programming stem cells with novel genetic tools to control genes and pathways that result in changes in stem cell fate decisions\, in addition to reprogramming terminally differentiated cells to function as unique therapeutic diagnostic and delivery vehicles. \nBIOGRAPHY: \nDr. Tara Deans received her PhD from Boston University in Biomedical Engineering. Following her postdoctoral training at Johns Hopkins University\, she became an Assistant Professor in Biomedical Engineering at the University of Utah. Currently\, Dr. Deans runs an applied mammalian synthetic biology laboratory where her lab focuses on building novel genetic tools to study the mechanisms of stem cell differentiation for the purpose of directing cell fate decisions. Recently\, Dr. Deans received four prestigious awards to support this area of research: the NSF CAREER Award\, the Office of Naval Research (ONR) Young Investigator Award\, the NIH Trailblazer Award\, and an NIH Director’s New Innovator Award. In addition to her research\, Dr. Deans was named a STEM Ambassador in the STEM Ambassador Program (STEMAP) at the University of Utah to engage underrepresented groups in STEM fields.  \nPlease email Elizabeth Chesley at e.chesley@northeastern.edu for the seminar link.
URL:https://coe.northeastern.edu/event/bioe-seminar-series-presents-tara-deans/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200930T123000
DTEND;TZID=America/New_York:20200930T130000
DTSTAMP:20260417T071912
CREATED:20200925T201515Z
LAST-MODIFIED:20200925T201515Z
UID:22403-1601469000-1601470800@coe.northeastern.edu
SUMMARY:ChE Seminar: "Engineering Innervated Organ Systems"
DESCRIPTION:ChE Seminar Series Presents:   \nRyan Koppes\, Ph.D. \nAssistant Professor\, Department of Chemical Engineering\, Northeastern University\, Boston\, MA \n“Engineering Innervated Organ Systems” \nAbstract:   \nMicrophysiological systems (MPS) hold the potential to provide benchtop models to investigate fundamental biology and disease while reducing the need for animal models. However\, many conventional in vitro models fail to fully capture the complex cell-cell interactions\, 3D microenvironments\, structural organization\, or vascularization of multicellular organ systems. A key criterion for replicating physiologically relevant architectures in a dish is the ability to compartmentalize discrete cell populations\, extracellular matrix compositions\, and/or mechanical properties\, without meaningfully restricting auto- and paracrine signaling. Traditionally\, compartmentalization within MPS has relied on the use of posts or microtunnels fabricated in silicon-based materials\, often requiring expensive lithographic capabilities. Further\, these methods are commonly limited to confining discrete tissues in the x-y plane. Towards overcoming these limitations\, we have developed a new ‘cut & assemble’ manufacturing technique. We have utilized these new tools to establish a number of MPS platforms to model the cardiovascular system. As part of this talk\, I will highlight the potential of this new technology and how we have applied it to model the heart and the adrenal medulla at the benchtop. Further\, through our work\, I will demonstrate how important the inclusion of neuron populations are for recapitulating organ function. \nBiography: \nDr. Ryan Koppes has been an Assistant Professor at Northeastern University since 2015\, where he has founded the Laboratory for Neuromodulation and Neuromuscular Repair (LNNR). Ryan received his Ph.D. in Biomedical Engineering from Rensselaer Polytechnic Institute (RPI) in Troy\, New York in 2013. His doctoral research with Dr. David Corr focused on soft musculoskeletal biomechanics and tissue engineering. In 2013\, Dr. Koppes joined the Bioelectronics Laboratory with Dr. Polina Anikeeva in Material Science and Engineering at MIT\, where he worked as a Translational Fellow on neural interface technology utilizing a multimaterial thermal drawing process and optogenetics. He was the recipient of the NIH R21 Trailblazer in 2017\, is a co-investigator on a 2019 AHA Innovative Project Award\, an NSF I-Corps\, and is a co-investigator on a 2020 NIH BRAIN Initiative R01 between Northeastern\, UCLA\, and Boston Children’s Hospital. Dr. Koppes also enjoys teaching Chemical Engineering Experimental Design Lab II (Unit Operations II) for senior engineers\, as well as mentoring undergraduates in the laboratory. \nPlease email Alyssa Ramsey at a.ramsey@northeastern.edu for the link to the seminar.
URL:https://coe.northeastern.edu/event/che-seminar-engineering-innervated-organ-systems/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200930T160000
DTEND;TZID=America/New_York:20200930T190000
DTSTAMP:20260417T071912
CREATED:20200928T180610Z
LAST-MODIFIED:20200928T180610Z
UID:22428-1601481600-1601492400@coe.northeastern.edu
SUMMARY:Cornell University Graduate and Professional School Fair
DESCRIPTION:Join the Graduate Admissions team at the Cornell Graduate Professional School Day. They will be available to answer your admissions and program questions. This event will take place on September 30\, 2020 from 4pm-7pm virtually.
URL:https://coe.northeastern.edu/event/cornell-university-graduate-and-professional-school-fair/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201001T120000
DTEND;TZID=America/New_York:20201001T130000
DTSTAMP:20260417T071912
CREATED:20200923T140841Z
LAST-MODIFIED:20200923T140841Z
UID:22381-1601553600-1601557200@coe.northeastern.edu
SUMMARY:Virtual Heads Up Lunchtime Funtime
DESCRIPTION:Graduate Student Services is hosting a Heads Up Virtual “lunchtime funtime” event for Master’s students to get to know each other and play an exciting competition against each other on October 1st\, 12-1pm EST!  Heads Up is a game where one student in a group will have to guess 10 words within a category with the help of their group members.  You will need to register via the Zoom link we will send out shortly to students to attend the event.
URL:https://coe.northeastern.edu/event/virtual-heads-up-lunchtime-funtime/
ORGANIZER;CN="Graduate School of Engineering":MAILTO:coe-gradadmissions@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201002T120000
DTEND;TZID=America/New_York:20201002T130000
DTSTAMP:20260417T071912
CREATED:20200916T193727Z
LAST-MODIFIED:20200916T193727Z
UID:22269-1601640000-1601643600@coe.northeastern.edu
SUMMARY:Bioengineering Works in Progress Student Seminar Series
DESCRIPTION:This virtual seminar series is an opportunity for Bioengineering graduate students to present their research. The first presenter is Shira Tsour from the Slavov lab. Title: “Quantifying rates of mistranslation”. The second presenter is Richard Huffman from the Slavov lab. Title: “Increased Sensitivity\, Reliability\, and Consistency of Single-Cell Proteomics Measurements via Targeted LC-MS/MS Methods”. Please email Danielle at d.freshnock@northeastern.edu for the link to the seminar.
URL:https://coe.northeastern.edu/event/bioengineering-works-in-progress-student-seminar-series-4/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201005T100000
DTEND;TZID=America/New_York:20201005T150000
DTSTAMP:20260417T071912
CREATED:20200928T180703Z
LAST-MODIFIED:20200928T180703Z
UID:22432-1601892000-1601910000@coe.northeastern.edu
SUMMARY:Rose-Hulman Institute of Technology Virtual Fall Career Fair
DESCRIPTION:Join the Graduate Admissions team at the Rose Hulman Institute of Technology Virtual Fall Career Fair. They will be available to answer your admissions and program questions. This event will take place on October 5 from 10:00-3:00pm virtually.
URL:https://coe.northeastern.edu/event/rose-hulman-institute-of-technology-virtual-fall-career-fair/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201005T100000
DTEND;TZID=America/New_York:20201005T150000
DTSTAMP:20260417T071912
CREATED:20200928T180752Z
LAST-MODIFIED:20200928T180752Z
UID:22434-1601892000-1601910000@coe.northeastern.edu
SUMMARY:Big Ten + Graduate School Expo
DESCRIPTION:Join the Graduate Admissions team at the Big Ten + Graduate School Expo hosted by Purdue University. They will be available to answer your admissions and program questions. This event will take place on October 5th virtually.
URL:https://coe.northeastern.edu/event/big-ten-graduate-school-expo-2/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201005T120000
DTEND;TZID=America/New_York:20201005T124500
DTSTAMP:20260417T071912
CREATED:20200828T214800Z
LAST-MODIFIED:20200828T214800Z
UID:22031-1601899200-1601901900@coe.northeastern.edu
SUMMARY:Getting Started with EndNote for Windows
DESCRIPTION:Start your fall 2020 research off on the right foot with Snell Library’s series of online workshops about citation management! In this session\, learn how to use EndNote for Windows to help you manage citations for yourself or your research group. \nRegister here: bit.ly/citationmgmtworkshops
URL:https://coe.northeastern.edu/event/getting-started-with-endnote-for-windows/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201006T120000
DTEND;TZID=America/New_York:20201006T120000
DTSTAMP:20260417T071912
CREATED:20201002T134710Z
LAST-MODIFIED:20201002T134710Z
UID:22494-1601985600-1601985600@coe.northeastern.edu
SUMMARY:ECE PhD Dissertation Defense: Mahsa Bayati
DESCRIPTION:PhD Defense: Efficient Data Access with Heterogeneous Computing using GPUs and Direct Non-volatile Storage. \nMahsa Bayati \nLocation: Zoom Link \nAbstract: The amount of data being collected that requires analysis is growing at an exponential rate. Along with this growth comes an increasing need for storage and computation. Researchers address these needs by (I) deploying distributed bigdata platforms equipped with cutting-edge storage devices\, and (II) building heterogeneous clusters with Central Processing Units (CPUs) and computational accelerators such as Graphics Processing Units (GPUs). The high performance of these mainstream systems is achieved by efficiently accessing data and computation resources and scheduling parallel and distributed tasks. \nThe performance of each job depends on the characteristics of both the application and the underlying storage and computational environments. However\, it is not a trivia to maintain efficiency and provide high performance in these mainstream systems. First\, in bigdata platforms like Spark and Hadoop\, full utilization of Solid State Devices (SSDs)\, i.e.\, Non-Volatile Memory Express (NVMe) and Key-Value (KV) SSDs is challenging. Data communication between Spark tasks\, levels of parallelism\, and resource co-location significantly affects achieving high I/O throughput. Second\, in heterogeneous systems\, one of the main bottlenecks of GPU computation is the data transfer bandwidth to GPUs in I/O intensive applications. The traditional GPU approach gets data from host memory\, which can limit data throughput and processing and thus degrade end-to-end performance. In this work\, we initially explore different attributes to exploit the full benefits of various SSDs in bigdata platforms. We then focus on mitigating the data transfer bottleneck in a heterogeneous bigdata framework. \nWe build a heterogeneous framework that facilitates GPU direct access to storage. Our framework aims to minimize the data transfer delay\, thus enhancing the performance of distributed and parallel tasks to obtain the full benefits of compute and storage resources. Our heterogeneous cluster is supplied with CPUs and GPUs as computing resources and non-volatile flash-based drives as storage resources. We also deploy the Spark bigdata platform to execute large workloads over our cluster. We then adopt a novel technique (e.g.\, Peer-to-Peer Direct Memory Access) to connect GPUs to non-volatile storage directly. Experimental results reveal that our heterogeneous Spark platform successfully bypasses the host memory and enables GPUs to communicate directly to the NVMe drive\, thus achieving higher data transfer throughput. The contributions of the dissertation are: (I) Realizing that bigdata processing applications need to consider framework features and application characteristics to fully utilize the high bandwidth of modern SSDs\, where compute and storage locality is essential to optimize the cost and performance. (II) Deploying our novel heterogeneous framework supporting GPU direct storage access improves data communication time around 35%- 50% and end-to-end performance by 30%.
URL:https://coe.northeastern.edu/event/ece-phd-dissertation-defense-mahsa-bayati/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201006T180000
DTEND;TZID=America/New_York:20201006T190000
DTSTAMP:20260417T071912
CREATED:20200930T184028Z
LAST-MODIFIED:20200930T184028Z
UID:22476-1602007200-1602010800@coe.northeastern.edu
SUMMARY:Galante Info Session
DESCRIPTION:Join the Galante Engineering Business Program for the first virtual info session of the semester on Tuesday\, October 6th from 6:00pm – 7:00pm via Zoom. During this meeting\, you will listen to a short presentation and also hear from a team of panelists that is made up of current students in the program. This is a great opportunity to ask questions and learn more about the various benefits of the program. Please RSVP by clicking this Link.
URL:https://coe.northeastern.edu/event/galante-info-session-2/
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20201007
DTEND;VALUE=DATE:20201008
DTSTAMP:20260417T071912
CREATED:20200928T180847Z
LAST-MODIFIED:20200928T180847Z
UID:22436-1602028800-1602115199@coe.northeastern.edu
SUMMARY:Olin College Fall Career Fair
DESCRIPTION:Join the Graduate Admissions team at the Olin College Fall Career Fair. They will be available to answer your admissions and program questions. This event will take place on October 7\, 2020\, virtually.
URL:https://coe.northeastern.edu/event/olin-college-fall-career-fair/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201007T120000
DTEND;TZID=America/New_York:20201007T123000
DTSTAMP:20260417T071912
CREATED:20201005T151209Z
LAST-MODIFIED:20201005T151209Z
UID:22557-1602072000-1602073800@coe.northeastern.edu
SUMMARY:ChE Seminar Series Presents: “Engineering the intestinal and retinal microenvironments”
DESCRIPTION:ChE Seminar Series Presents:\n \nRebecca Carrier\, Ph.D. \nProfessor & Associate Chair of Research\, Department of Chemical Engineering \nAffiliated Faculty\, Bioengineering\, Northeastern University\, Boston\, MA \n“Engineering the intestinal and retinal microenvironments” \nAbstract: The Advanced Drug Delivery Lab conducts research in regenerative medicine\, with a focus on intestinal and retinal tissue engineering\, and in oral drug delivery\, with a focus on enabling effective oral delivery of therapeutics. In the area of enabling effective oral drug delivery\, we have developed an experimental and theoretical framework to predict the impact of ingested lipids\, in food or drug delivery systems\, on oral drug absorption. This work could have a significant impact on societal health by providing practical\, relevant guidance for the oral dosing of drugs and nutritive supplements. As part of our efforts in enabling effective oral treatments\, we have explored the barrier properties of the gastrointestinal mucus barrier\, and revealed changes in the mucus barrier certain disease states. The lab is now exploring how to alter mucus barrier properties to potentially prevent certain diseases\, including necrotizing enterocolitis. In the area of intestinal tissue engineering\, we are developing human in vitro models of the microbiome-gut-immune axis for understanding the impact of what we ingest and the microbiome on human health. We are also developing biomaterial cell carriers for cell-therapy based retinal regeneration strategies\, with a focus on engineering cues into biomaterial carriers that will promote the survival and integration of implanted cells. \nBiosketch: Rebecca Carrier is a Professor in the Department of Chemical Engineering at Northeastern. She earned a BS in Chemical Engineering from Rensselaer Polytechnic Institute in 1995\, and a Ph.D. in Chemical Engineering from the Massachusetts Institute of Technology in 2000\, where she worked as a pioneer in cardiac muscle tissue engineering. After completing her graduate studies\, Rebecca worked at Pfizer\, Inc.\, as a Senior Research Scientist in oral controlled release drug delivery. She joined Northeastern in 2003\, and the overall theme of her research interests is the interaction between biological systems and materials\, with specific applications in drug delivery and regenerative medicine. She has worked with multiple industrial partners including Pfizer\, Merck\, and Boehringer Ingelheim\, and has received honors including the NSF CAREER award\, NU “Outstanding Teacher (2011)\,” “Faculty Fellow (2014)\,” and Soren Buus Outstanding Research (2017) Awards for excellence in teaching and research leadership. She was also invited to participate in the National Academy of Engineering Frontiers of Engineering (2016) and Frontiers of Engineering Education (2013) Symposia\, served as the Member-At-Large for the Society for Biomaterials from 2018-2019\, and was inducted into the American Institute for Medical and Biological Engineering in 2019. \nPlease email Alyssa Ramsey at a.ramsey@northeastern.edu for the link to the seminar.
URL:https://coe.northeastern.edu/event/che-seminar-series-presents-engineering-the-intestinal-and-retinal-microenvironments/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201007T120000
DTEND;TZID=America/New_York:20201007T130000
DTSTAMP:20260417T071912
CREATED:20200918T175635Z
LAST-MODIFIED:20200918T175635Z
UID:22325-1602072000-1602075600@coe.northeastern.edu
SUMMARY:BioE Seminar Series Presents: Wayne Mitzner
DESCRIPTION:Wayne Mitzner\, Ph.D. \nProfessor and Associate Chair for Research in the Department of Environmental Health & Engineering\, Johns Hopkins University Bloomberg School of Public Health\, Baltimore Maryland  \n“New Insights into Lung Anatomy” \nABSTRACT:   \nWe have utilized an optical clearing method to allow visualization of a heretofore undescribed subpleural acinar structural organization in the mammalian lung.  The clearing method enables visualization of the lung structure 40-50 alveoli deep below the visceral pleura in intact inflated lungs.  In addition to confirming previous observations that the immediate subpleural alveoli are uniform in appearance\, we document for the first time that the subpleural lung parenchyma is much more uniformly organized than the internal parenchyma.  Specifically\, below the surface layer of alveoli\, there is a striking parallel arrangement of alveolar ducts that all run perpendicular to the visceral pleural surface.  A three dimensional visualization of alveolar ducts allowed for a calculation of the average inner to outer duct diameter ratio of 0.53 in these subpleural ducts. This unique\, self-organizing parallel duct structure likely impacts both elastic recoil and the transmission of tethering forces in healthy and diseased lungs. \nBIOGRAPHY: \nWayne Mitzner is Professor and Associate Chair for Research in the Department of Environmental Health & Engineering at the Johns Hopkins University Bloomberg School of Public Health.  Dr. Mitzner’s research interests are focused on the structural basis of physiologic and pathologic phenotypes in the lung.  He also has a keen interest in developing methods to assess and quantify pulmonary function in preclinical models\, and has chaired several minisymposia and postgraduate courses in this area.  These functional studies are directed toward investigating the best ways to evaluate pathologic processes after acute and long-term exogenous insults to the lung.  His work has had continuous funding from the NIH for the past 30 years and is supported by over 300 research publications.  \nPlease email Elizabeth Chesley at e.chesley@northeastern.edu for the seminar link.  
URL:https://coe.northeastern.edu/event/bioe-seminar-series-presents-wayne-mitzner/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201007T123000
DTEND;TZID=America/New_York:20201007T130000
DTSTAMP:20260417T071912
CREATED:20201005T151425Z
LAST-MODIFIED:20201005T151523Z
UID:22560-1602073800-1602075600@coe.northeastern.edu
SUMMARY:ChE Seminar Series Presents: “Engineering Bacteria to Solve Problems in Renewable Chemical Production and Human Health”
DESCRIPTION:ChE Seminar Series Presents:\n \nBenjamin M. Woolston\, PhD \nAssistant Professor\, Department of Chemical Engineering\, Northeastern University\, Boston \, MA \n“Engineering Bacteria to Solve Problems in Renewable Chemical Production and Human Health” \nAbstract: The synthetic biology revolution has given us the ability to genetically reprogram microbes to serve a wide variety of purposes – from miniscule chemical factories that orchestrate exquisitely selective enzymatic pathways to produce fuels\, pharmaceuticals and polymers from simple raw materials – to biological computers that can sense their chemical environment and implement complex decision-making algorithms. The overall goal of the Woolston lab is to harness this potential for applications in renewable energy production and the human gut microbiota. In this talk\, I will present an overview of the two major current thrusts of the lab: In the first\, we are engineering anaerobic bacteria for the conversion of renewable single-carbon feedstocks to biofuels\, taking advantage of a number of economic and ethical benefits of using these substrates compared to 1st and 2nd generation biofuel efforts. In the second\, we are developing engineered microbes that can sense and correct an overabundance of the microbially derived metabolite hydrogen sulfide in the human gut; a toxic\, volatile molecule implicated in the onset of IBD and colorectal cancer. As well as the exciting applied potential of the resultant technology\, these efforts will also provide us with model systems with which to answer broader fundamental questions about microbial metabolism. \nBiography: Dr. Woolston joined the NEU Chemical Engineering department as an Assistant Professor in January 2020. As an NSF Graduate Research Fellow\, Dr. Woolston received his PhD in Chemical Engineering in 2017 from MIT under the guidance of Prof. Greg Stephanopoulos\, where his research focused on the development of genetic tools to enable metabolic engineering in anaerobic CO2-fixing microbes\, and the establishment of a methanol utilization pathway in the model organism Escherichia coli. While at MIT\, he was an inaugural Fellow of the Chemical Engineering Communication Lab\, where he provided peer tutoring and department-wide workshops to assist students and post-docs with aspects of scientific communication. His Post-doctoral work was conducted in the laboratory of Prof. Emily Balskus in the Chemistry & Chemical Biology department at Harvard University\, where he studied microbial metabolic pathways and enzymes that contribute to the stability of health-associated Lactobacilli in the human vaginal microbiota. At Northeastern\, his research program combines approaches from his previous research training in metabolic engineering\, synthetic biology\, biochemistry and microbiology to engineer microbes for biofuel & biochemical production\, and as diagnostics and therapeutics in the Human gut microbiota. His lab team currently consists of three graduate students and two undergraduates. Since joining NEU\, Dr. Woolston has taught the Biochemical Engineering senior elective (CHME 5630) and the graduate course in Kinetics & Reactor Design (CHME 7340). \nPlease email Alyssa Ramsey at a.ramsey@northeastern.edu for the link to the seminar.
URL:https://coe.northeastern.edu/event/che-seminar-series-presents-engineering-bacteria-to-solve-problems-in-renewable-chemical-production-and-human-health/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201008T120000
DTEND;TZID=America/New_York:20201008T124500
DTSTAMP:20260417T071912
CREATED:20200828T214826Z
LAST-MODIFIED:20200828T214826Z
UID:22038-1602158400-1602161100@coe.northeastern.edu
SUMMARY:Getting Started with RefWorks
DESCRIPTION:Start your fall 2020 research off on the right foot with Snell Library’s series of online workshops about citation management! In this session\, learn how to use RefWorks to help you manage citations for yourself or your research group. \nRegister here: bit.ly/citationmgmtworkshops
URL:https://coe.northeastern.edu/event/getting-started-with-refworks/2020-10-08/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201008T120000
DTEND;TZID=America/New_York:20201008T130000
DTSTAMP:20260417T071912
CREATED:20201002T194950Z
LAST-MODIFIED:20201002T194950Z
UID:22522-1602158400-1602162000@coe.northeastern.edu
SUMMARY:BioE Seminar Series Presents: Aileen Huang-Saad
DESCRIPTION:Aileen Huang-Saad\, Ph.D.\, MBA \nAssociate Professor\, Biomedical Engineering\, Entrepreneurship\, and Engineering Education\, University of Michigan\, Ann Arbor MI  \n“Closing the Gap Between Theory and Practice: Rethinking Engineering Education in Real-Time” \nABSTRACT:   \nDespite 20 years of focus on organizational change and effective educational best practices in STEM higher education\, significant research findings have had minimal influences on practice.  In 2016\, the University of Michigan BME Department sought to disrupt engineering education. Informed by organizational change theory\, we asked: 1) Is there potential for change; 2) what strategies facilitate change\, and 3) how can these strategies be implemented? As a result\, we developed an Instructional Design Sequence\, a new approach to instruction in which students\, post-docs\, and faculty create short Modules that use evidence-based teaching practices to expose BME students to BME professional practice.  This talk describes how the Sequence was conceived of and demonstrates how organizational theory\, entrepreneurship\, and design can be used to inform education practice. The resultant Sequence has the potential to be a transferrable model for transforming engineering education\, offering a new mechanism for integrating career-relevant curriculum into undergraduate curriculum in real-time\, while training future educators in instructional evidence-based practices. \nBIOGRAPHY: \nDr. Huang-Saad is faculty in the Department of Biomedical Engineering and Engineering Education at the University of Michigan. Dr. Huang-Saad has a thirteen-year history of bringing about organizational change in higher education\, leveraging evidence-based practices. She created the U-M BME graduate design program\, co-founded the U-M College of Engineering Center for Entrepreneurship\, launched the U-M National Science Foundation (NSF) I-Corps Node\, and developed the U-M BME Instructional Incubator. She is a canonical instructor for both the NSF and National Institute of Health (NIH) I-Corps Programs. Dr. Huang-Saad has received numerous awards for her teaching and student advising\, including the 1938E College of Engineering Award\, the Thomas M. Sawyer\, Jr. Teaching Award\, the U-M ASEE Outstanding Professor Award\, the International Teaching with Sakai Innovation Award\, and the College of Engineering Outstanding Student Advisor Award.  \nDr. Huang-Saad’s current research areas are entrepreneurship\, innovation\, and transforming higher education.  She is funded by the NSF to explore the influence of the microenvironment of entrepreneurship education on minoritized populations\, entrepreneurial ecosystems\, and fostering graduate student professional development.   \nPrior to joining the University of Michigan faculty\, Dr. Huang-Saad worked in industry gaining experience in new venture biotech\, the defense industry\, and medical device testing.  She has a Bachelor of Science in Engineering from the University of Pennsylvania\, a Doctor of Philosophy from The Johns Hopkins University School of Medicine\, and a Master of Business Administration from the University of Michigan Ross School of Business. \nIf interested in attending\, please email Elizabeth Chesley at e.chesley@northeastern.edu \n 
URL:https://coe.northeastern.edu/event/bioe-seminar-series-presents-aileen-huang-saad/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201009T120000
DTEND;TZID=America/New_York:20201009T124500
DTSTAMP:20260417T071912
CREATED:20200828T214920Z
LAST-MODIFIED:20200828T214920Z
UID:22047-1602244800-1602247500@coe.northeastern.edu
SUMMARY:Getting Started with EndNote for Mac
DESCRIPTION:Start your fall 2020 research off on the right foot with Snell Library’s series of online workshops about citation management! In this session\, learn how to use EndNote for Mac to help you manage citations for yourself or your research group. \nRegister here: bit.ly/citationmgmtworkshops
URL:https://coe.northeastern.edu/event/getting-started-with-endnote-for-mac/2020-10-09/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201009T120000
DTEND;TZID=America/New_York:20201009T130000
DTSTAMP:20260417T071912
CREATED:20200916T193834Z
LAST-MODIFIED:20200916T193834Z
UID:22271-1602244800-1602248400@coe.northeastern.edu
SUMMARY:Bioengineering Works in Progress Student Seminar Series
DESCRIPTION:This virtual seminar series is an opportunity for Bioengineering graduate students to present their research. The first presenter is Yifang Liu from the Rouhanifard lab. Title: “Defining cell states based on stochastic transcription”. The second presenter is Max Winkelman from the Dai lab. Title: “Bioengineered Neurovascular Niche Supports Neural Stem Cell Proliferation and Neurogenesis”. Please email Danielle at d.freshnock@northeastern.edu for the link to the seminar.
URL:https://coe.northeastern.edu/event/bioengineering-works-in-progress-student-seminar-series-5/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201012T130000
DTEND;TZID=America/New_York:20201012T140000
DTSTAMP:20260417T071912
CREATED:20201005T144512Z
LAST-MODIFIED:20201005T144512Z
UID:22553-1602507600-1602511200@coe.northeastern.edu
SUMMARY:ECE PhD Proposal Review: Muhamed Yildiz
DESCRIPTION:PhD Proposal Review: Interpretable Machine Learning for Retinopathy of Prematurity \nMuhamed Yildiz \nLocation: Zoom Link \nAbstract: Retinopathy of Prematurity (ROP)\, a leading cause of childhood blindness\, is diagnosed by clinical ophthalmoscopic examinations or reading retinal images. Plus disease\, defined as abnormal tortuosity and dilation of the posterior retinal blood vessels\, is the most important feature to determine treatment-requiring ROP. State-of-the-art ROP detection systems employ convolutional neural networks (CNNs) and achieve up to $0.947$ and $0.982$ area under the ROC curve (AUC) in the discrimination of and levels of ROP. However\, due to their black-box nature\, clinicians are reluctant to trust diagnostic predictions of CNNs. \nFirst\, we aim to create an interpretable\, feature extraction-based pipeline\, namely\, I-ROP ASSIST\, that achieves CNN like performance when diagnosing plus disease from retinal images. Our method segments retinal vessels\, detects the vessel centerlines. Then\, our method extracts features relevant to ROP\, including tortuosity and dilation measures\, and uses these features for classification via logistic regression\, support vector machines and neural networks to assess a severity score for the input. For predicting and levels of ROP on a dataset containing 5512 posterior retinal images\, we achieve $0.88$ and $0.94$ AUC\, respectively. Our system combining automatic retinal vessel segmentation\, tracing\, feature extraction and classification is able to diagnose plus disease in ROP with CNN like performance. \nFurthermore\, we aim to address the interpretability problem of CNN-based ROP detection system. Incorporating visual attention capabilities in CNNs enhances interpretability by highlighting regions in the images that CNNs utilize for prediction. Generic visual attention methods do not leverage structural domain information such as tortuosity and dilation of retinal blood vessels in ROP diagnosis. We propose the Structural Visual Guidance Attention Networks (SVGA-Net) method\, that leverages structural domain information to guide visual attention in CNNs. SVGA-Net achieves $0.979$ and $0.987$ AUC to predict and levels of ROP. Moreover\, SVGA-Net consistently results in higher AUC compared to visual attention CNNs without guidance\, baseline CNNs\, and CNNs with structured masks.
URL:https://coe.northeastern.edu/event/ece-phd-proposal-review-muhamed-yildiz/
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201012T140000
DTEND;TZID=America/New_York:20201012T150000
DTSTAMP:20260417T071912
CREATED:20201006T192350Z
LAST-MODIFIED:20201006T192350Z
UID:22584-1602511200-1602514800@coe.northeastern.edu
SUMMARY:ECE PhD Proposal Review: Sara Banian
DESCRIPTION:PhD Proposal Review: Content-Aware Design Assistance Frameworks for Graphic Design Layouts \nSara Banian \nLocation: Zoom Link \nAbstract: Layout is an important visual communication factor in graphic design that encompasses a page’s overall composition. During the different design stages\, designers express their requirements through images describing the interface’s visual layout\, hierarchical structure\, and content. They create wireframe layouts to meet user requirements and find relative design examples to gain inspiration and explore design alternatives. This is not only an iterative process\, but also a time-consuming one. \nIn this proposal\, we aim to design and evaluate design assistance methodologies to augment the process of layout design with a particular focus on visual search and wireframe creation in the context of mobile User Interface (UI) deign. For visual search\, we investigate how to find design examples that are relative to the design requirements of a UI layout. Layout retrieval is different from pixel-level image retrieval\, as it requires processing both the spatial layout and the content of the data to retrieve similar images. To achieve this\, I explore the problem of user interface image retrieval from both the data and the model side\, by collecting a more highly annotated\, well-suited dataset and proposing an object-detection based image retrieval model. The model takes as input a user interface image and retrieves the visually similar design examples. It uses object detection to identify the user interface components\, performs semantic segmentation to produce a hierarchical structure\, and trains an attention-aware multi-modal embedding network that leans the structure and content of the given layout design for relevant image retrieval. Results show that the system is capable of retrieving relative design examples through content analysis. Next\, I propose a generative framework to investigate how to generate layout wireframes according to user specifications and following common design practices and conventions. The generative framework aims at modeling the content of the UI layouts taking into account different layout variations and design features.
URL:https://coe.northeastern.edu/event/ece-phd-proposal-review-sara-banian/
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201013T080000
DTEND;TZID=America/New_York:20201013T170000
DTSTAMP:20260417T071912
CREATED:20201013T204855Z
LAST-MODIFIED:20201013T204855Z
UID:22790-1602576000-1602608400@coe.northeastern.edu
SUMMARY:ChE Seminar Series Presents: Joshua Gallaway
DESCRIPTION:Joshua Gallaway\, Ph.D. \nDiPietro Assistant Professor \nDepartment of Chemical Engineering\, Northeastern University\, Boston\, MA \n“Next Generation for the Grid”  \nAbstract: In our lab\, we study mechanisms within complex electrochemical systems. Practical electrochemical systems such as batteries\, sensors\, and fuel cells are often complex\, involving engineered high surface area electrodes\, starved electrolyte conditions\, phase transformations\, and interplay of the two electrodes. For these reasons\, there are significant deviations from ideal behavior as well as emergent or unexpected phenomena. We seek to understand these to engineer better devices for broad societal benefit\, such as the worldwide adoption of sustainable energy. We have developed strategies for coupling electrochemical methods with materials synthesis\, theory\, and operando analysis techniques\, often based on high energy X-rays. This allows distributed and localized phenomena to be observed within operating electrochemical cells\, and fundamental mechanistic information to be extracted from within the complex system. Thus we have a laboratory equipped for modern electroanalytical study and also make use of specialized X-ray sources maintained by the US Department of Energy. Recent research has focused on low-cost and safe battery materials for electrical storage at the scale of the power grid. Intermittent renewables like solar and wind power will succeed if excess electricity can be stored safely without adding significantly to the cost. \nBiography: Joshua Gallaway has been an Assistant Professor at Northeastern University since 2017\, where he has founded the Analysis of Complex Electrochemical Systems Laboratory (ACES). He received his PhD in chemical engineering from Columbia University in 2007. Working with his advisor Prof. Scott Calabrese Barton\, he characterized the electron transfer rates of enzymes embedded in oxygen-reducing hydrogels. After his PhD work he completed a postdoctoral appointment with Prof. Alan West\, also at Columbia\, studying non-uniform current distributions in sub-micron interconnect features for the semiconductor industry. He then joined the newly-formed CUNY Energy Institute in a research position funded by the Wallis Foundation. There he worked on an ARPA-E funded project headed by Distinguished Professor Sanjoy Banerjee\, which resulted in the spin out company Urban Electric Power. His recent research has focused on using high energy synchrotron techniques to visualize non-uniform reactions within battery electrodes. \nPlease email Alyssa Ramsey at a.ramsey@northeastern.edu for the link to the seminar.
URL:https://coe.northeastern.edu/event/che-seminar-series-presents-joshua-gallaway/
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201013T120000
DTEND;TZID=America/New_York:20201013T124500
DTSTAMP:20260417T071912
CREATED:20200828T215002Z
LAST-MODIFIED:20200828T215002Z
UID:22054-1602590400-1602593100@coe.northeastern.edu
SUMMARY:Getting Started with Mendeley
DESCRIPTION:Start your fall 2020 research off on the right foot with Snell Library’s series of online workshops about citation management! In this session\, learn how to use Mendeley to help you manage citations for yourself or your research group. \nRegister here: bit.ly/citationmgmtworkshops
URL:https://coe.northeastern.edu/event/getting-started-with-mendeley/2020-10-13/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201014T120000
DTEND;TZID=America/New_York:20201014T123000
DTSTAMP:20260417T071912
CREATED:20201013T204557Z
LAST-MODIFIED:20201013T204625Z
UID:22787-1602676800-1602678600@coe.northeastern.edu
SUMMARY:ChE Seminar Series Presents: Richard West
DESCRIPTION:Richard West\, Ph.D.\nAssociate Professor\nDepartment of Chemical Engineering\, Northeastern University\, Boston\, MA \n“Detailed Kinetic Modeling: using computers to predict complex systems of chemical reactions” \nAbstract: The primary focus of our research is the development of detailed microkinetic models for complex reacting systems\, like combustion\, heterogeneous catalysis\, and bio-fuel processing. Our approach is to automate the discovery of reaction pathways\, and the calculation of key parameters using ab initio quantum chemistry calculations\, and novel machine learning techniques. These kinetic models will link to multi-scale models of the reactor systems so that the overall process can be understood and optimized as a whole. This approach towards microkinetic model development will then contribute to the optimization and understanding of catalytic processes\, leading to catalyst design and discovery\, as well as combustion processes\, leading to safer and greener fire suppressants\, refrigerants\, and fuels. Our approach to computational chemistry involves both learning chemistry from the computers\, and teaching chemistry to the computers. Learn more at neu.edu/comocheng. \nBiography: Richard read Chemical Engineering at the University of Cambridge\, completing his BA and MEng degrees in 2004. He was in the first cohort to spend a year at MIT on the undergraduate exchange program of the Cambridge-MIT Institute. He returned to MIT for a semester of graduate classes at the start of his PhD\, also in Chemical Engineering at the University of Cambridge. His thesis work\, in the Computational Modelling Group of Prof. Markus Kraft\, was on modeling the chloride process for the gas-phase synthesis of titanium dioxide nano particles. He finished in 2008 and returned to MIT once more\, this time as a postdoctoral research associate working with Prof. William Green to develop detailed kinetic models and the tools used to create them. In 2011 he moved across the river to Boston\, starting the Computational Modeling in Chemical Engineering group at Northeastern University. In 2018 he became an Associate Professor (with tenure) and the Associate Chair for Graduate Studies in the Department of Chemical Engineering\, a position he held until his sabbatical began in 2020. He lives with his wife (also NU faculty) and 5-year-old daughter in Brookline\, MA. You can follow his weird toast diet on Instagram (@richardhwest). \nPlease email Alyssa Ramsey at a.ramsey@northeastern.edu for the link to the seminar.
URL:https://coe.northeastern.edu/event/che-seminar-series-presents-richard-west/
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201014T120000
DTEND;TZID=America/New_York:20201014T124500
DTSTAMP:20260417T071912
CREATED:20200828T215040Z
LAST-MODIFIED:20200828T215040Z
UID:22059-1602676800-1602679500@coe.northeastern.edu
SUMMARY:Getting Started with Zotero
DESCRIPTION:Start your fall 2020 research off on the right foot with Snell Library’s series of online workshops about citation management! In this session\, learn how to use Zotero to help you manage citations for yourself or your research group. \nRegister here: bit.ly/citationmgmtworkshops
URL:https://coe.northeastern.edu/event/getting-started-with-zotero/2020-10-14/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201014T120000
DTEND;TZID=America/New_York:20201014T130000
DTSTAMP:20260417T071912
CREATED:20200929T200239Z
LAST-MODIFIED:20200929T200239Z
UID:22469-1602676800-1602680400@coe.northeastern.edu
SUMMARY:BioE Seminar Series Presents: Roger Kamm
DESCRIPTION:Roger Kamm\, Ph.D. \nCecil and Ida Green Distinguished Professor of Biological and Mechanical Engineering\, Massachusetts Institute of Technology\, Cambridge MA  \n“Metastasis on a chip: Effects of intravascular and transendothelial flow” \nABSTRACT:   \nMany CTCs fail to survive the voyage from the primary tumor to the metastatic site\, and die before they can initiate a new tumor.  Others not only survive\, but enter into the tissue where some fraction proliferate and spread.  We studied the effects of vascular flows\, both intravascular (IVF) and transendothelial (TEF) on tumor cell adhesion\, migration and transendothelial migration with the goal of better understanding how flow either promotes or impedes metastasis.  Our results show that CTCs migrate or are dragged in the direction of flow prior to trans-endothelial migration.  We also observe enhanced potential for TEM due to IVF.  TEF\, on the other hand\, has little effect on either migration of CTCs along the luminal surface of the endothelium or their propensity to undergo trans-endothelial migration\, but hastens the process once initiated.  TEF increased the migration speed of tumor cells post-extravasation\, and caused the cells to remain close to the outer endothelial surface. In summary\, both types of flow tend to promote a pro-metastatic phenotype. \nBIOGRAPHY: \nRoger Kamm is the Cecil and Ida Green Distinguished Professor of Biological and Mechanical Engineering at MIT\, where he has served on the faculty since 1978. Kamm has long been instrumental in developing research activities at the interface of biology and mechanics\, formerly in cell and molecular mechanics\, and now in engineered living systems.  Current interests are in developing models of healthy and diseased organ function using microfluidic technologies\, with a focus on vascularization.   \nPlease email Elizabeth Chesley at e.chesley@northeastern.edu for the seminar link.
URL:https://coe.northeastern.edu/event/bioe-seminar-series-presents-roger-kamm/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20201015
DTEND;VALUE=DATE:20201231
DTSTAMP:20260417T071912
CREATED:20201015T142444Z
LAST-MODIFIED:20201015T142444Z
UID:22804-1602720000-1609372799@coe.northeastern.edu
SUMMARY:Meet Your Graduate Student Ambassadors!
DESCRIPTION:Meet your Student Ambassadors! Prospective and Admitted Graduate Students are invited to meet their Student Ambassador via Unibuddy.
URL:https://coe.northeastern.edu/event/meet-your-graduate-student-ambassadors/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201015T110000
DTEND;TZID=America/New_York:20201015T150000
DTSTAMP:20260417T071912
CREATED:20200923T202124Z
LAST-MODIFIED:20200923T202124Z
UID:22392-1602759600-1602774000@coe.northeastern.edu
SUMMARY:Engineering Graduate School Virtual Fair
DESCRIPTION:Join the Graduate School of Engineering Admissions team at Career Echo’s Virtual Graduate School Fair for Engineering programs on October 15th from 11:00 am -3:00pm. Our admissions team will be available to speak about graduate MS\, PhD\, and Certificate Programs. \nRegister today!
URL:https://coe.northeastern.edu/event/engineering-graduate-school-virtual-fair/
ORGANIZER;CN="Graduate School of Engineering":MAILTO:coe-gradadmissions@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201015T160000
DTEND;TZID=America/New_York:20201015T170000
DTSTAMP:20260417T071912
CREATED:20201007T151555Z
LAST-MODIFIED:20201007T151555Z
UID:22588-1602777600-1602781200@coe.northeastern.edu
SUMMARY:ECE PhD Proposal Review: Maher Kachmar
DESCRIPTION:PhD Proposal Review: Active Resource Partitioning and Planning for Storage Systems using Time Series Forecasting and Machine Learning Techniques \nMaher Kachmar \nLocation: Zoom Link \nAbstract: In today’s enterprise storage systems\, supported data services such as snapshot delete or drive rebuild can result in tremendous performance overhead if executed inline along with heavy foreground IO\, often leading to missing Service Level Objectives (SLOs). Moreover\, static partitioning of storage systems resources such as CPU cores or memory caches may lead to missing Service Level Agreements (SLAs) such as data reduction rate (DRR). However\, typical storage system applications such as Virtual Desktop Infrastructure (VDI) or web services follow a repetitive workload pattern that can be learned and/or forecasted. Learning these workload pattern allows us to address several storage system resource partitioning and planning challenges that may not be overcome with traditional manual tuning and primitive feedback mechanism. \nWe propose a priority-based background scheduler that learns storage system workload repetitive pattern and allows storage systems to maintain peak performance and meet service level objectives (SLOs) while supporting a number of data services. When foreground IO demand intensifies\, system resources are dedicated to service foreground IO requests and any background processing that can be deferred are recorded to be processed in future idle cycles as long as our forecaster predicts that the storage pool has remaining capacity. The smart background scheduler adopts a resource partitioning model that allows both foreground and background IO to execute together as long as foreground IOs are not impacted\, harnessing any free cycles to clear background debt. Using traces from VDI and web services applications\, we show how our technique can out performance a static method that sets fixed limits on the deferred background debt and reduces SLO violations from 54.6% (when using a fixed background debt watermark)\, to only 6.2% when dynamically adjusted by our smart background scheduler. \nThis thesis also proposes a smart capacity planning and recommendation tool that ensures the right number of drives are available in the storage pool in order to meet both capacity and performance constrains without over-provisioning storage. Aided by forecasting models that characterizes workload pattern\, we can predict future storage pool utilization and drive over-wearing. Similarly\, to meet SLOs\, the tool recommends expanding pool space in order to defer more background work through larger debt bins. We also propose a content-aware learning cache (CALC) that uses machine learning techniques to actively partition the storage system cache between a deduplication data digest cache\, content cache\, and address based data cache to improve cache hit performance while maximizing data reduction rate (DRR).
URL:https://coe.northeastern.edu/event/ece-phd-proposal-review-maher-kachmar/
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