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X-ORIGINAL-URL:https://coe.northeastern.edu
X-WR-CALDESC:Events for Northeastern University College of Engineering
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250617T100000
DTEND;TZID=America/New_York:20250617T120000
DTSTAMP:20260424T230045
CREATED:20250529T202129Z
LAST-MODIFIED:20250529T202129Z
UID:51059-1750154400-1750161600@coe.northeastern.edu
SUMMARY:Graduate Student Proposal/Fellowship Writing Hours: CommLab Drop-In Hours
DESCRIPTION:Graduate students\, are you looking for support in writing your research or fellowship proposal?  Join the CommLab virtual drop-in writing hours any Tuesday between 10 am -12 pm ET and stay for a short time or the whole two hours.  A CommLab Fellow will be available to help you set writing goals and provide feedback on your writing.  Join this drop-in workshop through Zoom.
URL:https://coe.northeastern.edu/event/graduate-student-proposal-fellowship-writing-hours-commlab-drop-in-hours/2025-06-17/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250617T110000
DTEND;TZID=America/New_York:20250617T120000
DTSTAMP:20260424T230045
CREATED:20250529T202325Z
LAST-MODIFIED:20250715T141412Z
UID:51203-1750158000-1750161600@coe.northeastern.edu
SUMMARY:LinkedIn\, CV\, Resume: CommLab Drop-In Hours
DESCRIPTION:Graduate students\, do you need to increase your on-line presence or update your CV or Resume?  Join the CommLab’s LinkedIn\, CV\, and Resume drop-in workshops every other Tuesday from 11 pm to 12 pm ET. This collaborative space offers valuable advice and peer feedback to enhance your online profile and professional presence. Join this drop-in workshop through Zoom.
URL:https://coe.northeastern.edu/event/linkedin-cv-resume-commlab-drop-in-hours/2025-06-17/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250618T130000
DTEND;TZID=America/New_York:20250618T140000
DTSTAMP:20260424T230045
CREATED:20250529T201708Z
LAST-MODIFIED:20250529T201708Z
UID:51077-1750251600-1750255200@coe.northeastern.edu
SUMMARY:Scientific Oral Communication : CommLab Drop-In Workshops
DESCRIPTION:The NU CommLab is hosting a weekly hybrid Scientific Oral Communication Drop-in practice for graduate students. Drop-in virtually or in-person any week to practice for your upcoming oral exams\, proposals\, thesis\, dissertation or talks. Receive and implement feedback on your verbal and non-verbal public speaking skills. Meet any Wednesday from 1-2pm in 306 Egan or on Zoom. Note on June 4th the workshop will be in 206 Egan.
URL:https://coe.northeastern.edu/event/scientific-oral-communication-commlab-drop-in-workshops/2025-06-18/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250620T103000
DTEND;TZID=America/New_York:20250620T123000
DTSTAMP:20260424T230045
CREATED:20250611T170756Z
LAST-MODIFIED:20250611T170756Z
UID:51298-1750415400-1750422600@coe.northeastern.edu
SUMMARY:ChE PhD Dissertation Defense: Yujia Wang
DESCRIPTION:Name:\nYujia Wang \nTitle:\nMachine Learning and Spatially Resolved Spectroscopy for Controlled Synthesis and Novel Phenomena Discovery in Monolayer Molybdenum Disulfide \nDate:\n06/20/2024 \nTime:\n10:30:00 AM \nCommittee Members:\nProf. Swastik Kar (Advisor)\nProf. Joshua Gallaway\nProf. Steve Lustig\nProf. Francisco Hung \nLocation:\nBurlington Campus: Building 5\, Room C \nAbstract: \nTwo-dimensional (2D) materials\, particularly transition metal dichalcogenides like molybdenum disulfide (MoS2)\, represent a promising platform for next-generation semiconductor technologies due to their atomic-thin structure\, tunable electronic properties\, and unique optical characteristics. However\, realizing their full potential is hindered by two important challenges: the time-consuming\, trial-and-error nature of chemical vapor deposition (CVD) synthesis optimization\, and the difficulty in accurately characterizing spatially inhomogeneous material properties. In this dissertation defense\, I will present detailed investigations into the development of new methods for addressing these challenges through the integration of machine learning-guided synthesis and high-resolution spatially resolved optical characterization techniques. \nFirst\, I developed an experimental “hyperspace” design system that serves as an interface that adapts synthesis parameters to machine learning frameworks. The machine learning algorithms were developed through collaborations with Prof. Xiaoning (Sarah) Jin’s group (Department of Mechanical and Industrial Engineering). The algorithms efficiently identify pathways towards synthesis optimization in complex multidimensional experimental hyperspaces\, accelerating the synthesis towards the highest sample quality. Our results showed up to 85% reduction (two months instead of 1 year) in trial-and-error efforts\, and rapid optimization of the ideal synthesis conditions. \nSecond\, I established a spatially resolved optical spectroscopy platform for characterizing the as-grown 2D materials by combining Raman and photoluminescence (PL) mapping at micrometer resolution. Going much beyond traditional mapping techniques\, this technique enables simultaneous extraction of strain\, doping\, and excitonic properties across individual flakes\, revealing growth-intrinsic mechanisms for controlled engineering of electronic and optical properties. Through systematically varied CVD conditions\, I demonstrated deterministic control over both orbital bandgaps and spin-orbit coupling\, achieving the first purely optical experimental observation of strain-tunable spin-orbit splitting in as-grown monolayer MoS2. \nFinally\, I applied this integrated platform to explore iron-doped MoS2 – to further elucidate the role of doping in 2D semiconductors. This work established valuable synthesis protocols and identified distinctive optical signatures that serve as indicators of dopant incorporation in 2D materials. \nMy research demonstrates how coupling experimental design and scanning-based characterization approaches with advanced computational methods can substantially accelerate materials discovery and establish new pathways for deterministic property engineering in 2D semiconductors\, with implications extending to quantum technologies\, optoelectronics\, and spintronic applications.
URL:https://coe.northeastern.edu/event/che-phd-dissertation-defense-yujia-wang/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250624T090000
DTEND;TZID=America/New_York:20250624T110000
DTSTAMP:20260424T230045
CREATED:20250529T202415Z
LAST-MODIFIED:20250529T202415Z
UID:51021-1750755600-1750762800@coe.northeastern.edu
SUMMARY:Graduate Student Writing:  CommLab Drop-In Writing Hours
DESCRIPTION:Graduate students\, are you looking for a time for focused research writing?  Join the CommLab drop-in writing hours any Tuesday between 9 -11 am ET.  Drop in any Tuesday and stay for a short time or two hours.  A CommLab Fellow will be available to provide feedback on your writing.  We will be meeting virtually on Teams.
URL:https://coe.northeastern.edu/event/graduate-student-writing-commlab-drop-in-writing-hours/2025-06-24/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250624T100000
DTEND;TZID=America/New_York:20250624T120000
DTSTAMP:20260424T230045
CREATED:20250529T202129Z
LAST-MODIFIED:20250529T202129Z
UID:51060-1750759200-1750766400@coe.northeastern.edu
SUMMARY:Graduate Student Proposal/Fellowship Writing Hours: CommLab Drop-In Hours
DESCRIPTION:Graduate students\, are you looking for support in writing your research or fellowship proposal?  Join the CommLab virtual drop-in writing hours any Tuesday between 10 am -12 pm ET and stay for a short time or the whole two hours.  A CommLab Fellow will be available to help you set writing goals and provide feedback on your writing.  Join this drop-in workshop through Zoom.
URL:https://coe.northeastern.edu/event/graduate-student-proposal-fellowship-writing-hours-commlab-drop-in-hours/2025-06-24/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250624T110000
DTEND;TZID=America/New_York:20250624T120000
DTSTAMP:20260424T230045
CREATED:20250529T202325Z
LAST-MODIFIED:20250529T202325Z
UID:52659-1750762800-1750766400@coe.northeastern.edu
SUMMARY:LinkedIn\, CV\, Resume: CommLab Drop-In Hours
DESCRIPTION:Graduate students\, do you need to increase your on-line presence or update your CV or Resume?  Join the CommLab’s LinkedIn\, CV\, and Resume drop-in workshops every other Tuesday from 11 pm to 12 pm ET. This collaborative space offers valuable advice and peer feedback to enhance your online profile and professional presence. Join this drop-in workshop through Zoom.
URL:https://coe.northeastern.edu/event/linkedin-cv-resume-commlab-drop-in-hours/2025-06-24/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250625T130000
DTEND;TZID=America/New_York:20250625T140000
DTSTAMP:20260424T230045
CREATED:20250529T201709Z
LAST-MODIFIED:20250529T201709Z
UID:51078-1750856400-1750860000@coe.northeastern.edu
SUMMARY:Scientific Oral Communication : CommLab Drop-In Workshops
DESCRIPTION:The NU CommLab is hosting a weekly hybrid Scientific Oral Communication Drop-in practice for graduate students. Drop-in virtually or in-person any week to practice for your upcoming oral exams\, proposals\, thesis\, dissertation or talks. Receive and implement feedback on your verbal and non-verbal public speaking skills. Meet any Wednesday from 1-2pm in 306 Egan or on Zoom. Note on June 4th the workshop will be in 206 Egan.
URL:https://coe.northeastern.edu/event/scientific-oral-communication-commlab-drop-in-workshops/2025-06-25/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250701T090000
DTEND;TZID=America/New_York:20250701T110000
DTSTAMP:20260424T230045
CREATED:20250529T202415Z
LAST-MODIFIED:20250529T202415Z
UID:51022-1751360400-1751367600@coe.northeastern.edu
SUMMARY:Graduate Student Writing:  CommLab Drop-In Writing Hours
DESCRIPTION:Graduate students\, are you looking for a time for focused research writing?  Join the CommLab drop-in writing hours any Tuesday between 9 -11 am ET.  Drop in any Tuesday and stay for a short time or two hours.  A CommLab Fellow will be available to provide feedback on your writing.  We will be meeting virtually on Teams.
URL:https://coe.northeastern.edu/event/graduate-student-writing-commlab-drop-in-writing-hours/2025-07-01/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250701T100000
DTEND;TZID=America/New_York:20250701T120000
DTSTAMP:20260424T230045
CREATED:20250529T202130Z
LAST-MODIFIED:20250529T202130Z
UID:51061-1751364000-1751371200@coe.northeastern.edu
SUMMARY:Graduate Student Proposal/Fellowship Writing Hours: CommLab Drop-In Hours
DESCRIPTION:Graduate students\, are you looking for support in writing your research or fellowship proposal?  Join the CommLab virtual drop-in writing hours any Tuesday between 10 am -12 pm ET and stay for a short time or the whole two hours.  A CommLab Fellow will be available to help you set writing goals and provide feedback on your writing.  Join this drop-in workshop through Zoom.
URL:https://coe.northeastern.edu/event/graduate-student-proposal-fellowship-writing-hours-commlab-drop-in-hours/2025-07-01/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250701T110000
DTEND;TZID=America/New_York:20250701T120000
DTSTAMP:20260424T230045
CREATED:20250529T202325Z
LAST-MODIFIED:20250715T141413Z
UID:51204-1751367600-1751371200@coe.northeastern.edu
SUMMARY:LinkedIn\, CV\, Resume: CommLab Drop-In Hours
DESCRIPTION:Graduate students\, do you need to increase your on-line presence or update your CV or Resume?  Join the CommLab’s LinkedIn\, CV\, and Resume drop-in workshops every other Tuesday from 11 pm to 12 pm ET. This collaborative space offers valuable advice and peer feedback to enhance your online profile and professional presence. Join this drop-in workshop through Zoom.
URL:https://coe.northeastern.edu/event/linkedin-cv-resume-commlab-drop-in-hours/2025-07-01/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250702T130000
DTEND;TZID=America/New_York:20250702T140000
DTSTAMP:20260424T230045
CREATED:20250529T201709Z
LAST-MODIFIED:20250529T201709Z
UID:51079-1751461200-1751464800@coe.northeastern.edu
SUMMARY:Scientific Oral Communication : CommLab Drop-In Workshops
DESCRIPTION:The NU CommLab is hosting a weekly hybrid Scientific Oral Communication Drop-in practice for graduate students. Drop-in virtually or in-person any week to practice for your upcoming oral exams\, proposals\, thesis\, dissertation or talks. Receive and implement feedback on your verbal and non-verbal public speaking skills. Meet any Wednesday from 1-2pm in 306 Egan or on Zoom. Note on June 4th the workshop will be in 206 Egan.
URL:https://coe.northeastern.edu/event/scientific-oral-communication-commlab-drop-in-workshops/2025-07-02/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250708T090000
DTEND;TZID=America/New_York:20250708T110000
DTSTAMP:20260424T230045
CREATED:20250529T202415Z
LAST-MODIFIED:20250529T202415Z
UID:51023-1751965200-1751972400@coe.northeastern.edu
SUMMARY:Graduate Student Writing:  CommLab Drop-In Writing Hours
DESCRIPTION:Graduate students\, are you looking for a time for focused research writing?  Join the CommLab drop-in writing hours any Tuesday between 9 -11 am ET.  Drop in any Tuesday and stay for a short time or two hours.  A CommLab Fellow will be available to provide feedback on your writing.  We will be meeting virtually on Teams.
URL:https://coe.northeastern.edu/event/graduate-student-writing-commlab-drop-in-writing-hours/2025-07-08/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250708T100000
DTEND;TZID=America/New_York:20250708T120000
DTSTAMP:20260424T230045
CREATED:20250529T202131Z
LAST-MODIFIED:20250529T202131Z
UID:51062-1751968800-1751976000@coe.northeastern.edu
SUMMARY:Graduate Student Proposal/Fellowship Writing Hours: CommLab Drop-In Hours
DESCRIPTION:Graduate students\, are you looking for support in writing your research or fellowship proposal?  Join the CommLab virtual drop-in writing hours any Tuesday between 10 am -12 pm ET and stay for a short time or the whole two hours.  A CommLab Fellow will be available to help you set writing goals and provide feedback on your writing.  Join this drop-in workshop through Zoom.
URL:https://coe.northeastern.edu/event/graduate-student-proposal-fellowship-writing-hours-commlab-drop-in-hours/2025-07-08/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250708T110000
DTEND;TZID=America/New_York:20250708T120000
DTSTAMP:20260424T230045
CREATED:20250529T202325Z
LAST-MODIFIED:20250529T202325Z
UID:52660-1751972400-1751976000@coe.northeastern.edu
SUMMARY:LinkedIn\, CV\, Resume: CommLab Drop-In Hours
DESCRIPTION:Graduate students\, do you need to increase your on-line presence or update your CV or Resume?  Join the CommLab’s LinkedIn\, CV\, and Resume drop-in workshops every other Tuesday from 11 pm to 12 pm ET. This collaborative space offers valuable advice and peer feedback to enhance your online profile and professional presence. Join this drop-in workshop through Zoom.
URL:https://coe.northeastern.edu/event/linkedin-cv-resume-commlab-drop-in-hours/2025-07-08/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250709T130000
DTEND;TZID=America/New_York:20250709T140000
DTSTAMP:20260424T230045
CREATED:20250529T201710Z
LAST-MODIFIED:20250529T201710Z
UID:51080-1752066000-1752069600@coe.northeastern.edu
SUMMARY:Scientific Oral Communication : CommLab Drop-In Workshops
DESCRIPTION:The NU CommLab is hosting a weekly hybrid Scientific Oral Communication Drop-in practice for graduate students. Drop-in virtually or in-person any week to practice for your upcoming oral exams\, proposals\, thesis\, dissertation or talks. Receive and implement feedback on your verbal and non-verbal public speaking skills. Meet any Wednesday from 1-2pm in 306 Egan or on Zoom. Note on June 4th the workshop will be in 206 Egan.
URL:https://coe.northeastern.edu/event/scientific-oral-communication-commlab-drop-in-workshops/2025-07-09/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250714T163000
DTEND;TZID=America/New_York:20250714T180000
DTSTAMP:20260424T230045
CREATED:20250207T184252Z
LAST-MODIFIED:20250730T200913Z
UID:49312-1752510600-1752516000@coe.northeastern.edu
SUMMARY:Women in Engineering Book Club
DESCRIPTION:Join the Women in Engineering Book Club! \nWhen: 2nd of Monday of every month at 4:30pm \nWhere: Snell Library’s Research & Teaching Hub (SL 215) \nWhat we are reading: Women in Engineering Book Club – Book List
URL:https://coe.northeastern.edu/event/women-in-engineering-book-club/2025-07-14/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250715T090000
DTEND;TZID=America/New_York:20250715T110000
DTSTAMP:20260424T230045
CREATED:20250529T202416Z
LAST-MODIFIED:20250529T202416Z
UID:51024-1752570000-1752577200@coe.northeastern.edu
SUMMARY:Graduate Student Writing:  CommLab Drop-In Writing Hours
DESCRIPTION:Graduate students\, are you looking for a time for focused research writing?  Join the CommLab drop-in writing hours any Tuesday between 9 -11 am ET.  Drop in any Tuesday and stay for a short time or two hours.  A CommLab Fellow will be available to provide feedback on your writing.  We will be meeting virtually on Teams.
URL:https://coe.northeastern.edu/event/graduate-student-writing-commlab-drop-in-writing-hours/2025-07-15/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250715T100000
DTEND;TZID=America/New_York:20250715T120000
DTSTAMP:20260424T230045
CREATED:20250529T202132Z
LAST-MODIFIED:20250529T202132Z
UID:51063-1752573600-1752580800@coe.northeastern.edu
SUMMARY:Graduate Student Proposal/Fellowship Writing Hours: CommLab Drop-In Hours
DESCRIPTION:Graduate students\, are you looking for support in writing your research or fellowship proposal?  Join the CommLab virtual drop-in writing hours any Tuesday between 10 am -12 pm ET and stay for a short time or the whole two hours.  A CommLab Fellow will be available to help you set writing goals and provide feedback on your writing.  Join this drop-in workshop through Zoom.
URL:https://coe.northeastern.edu/event/graduate-student-proposal-fellowship-writing-hours-commlab-drop-in-hours/2025-07-15/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250715T110000
DTEND;TZID=America/New_York:20250715T120000
DTSTAMP:20260424T230045
CREATED:20250529T202325Z
LAST-MODIFIED:20250715T141413Z
UID:51205-1752577200-1752580800@coe.northeastern.edu
SUMMARY:LinkedIn\, CV\, Resume: CommLab Drop-In Hours
DESCRIPTION:Graduate students\, do you need to increase your on-line presence or update your CV or Resume?  Join the CommLab’s LinkedIn\, CV\, and Resume drop-in workshops every other Tuesday from 11 pm to 12 pm ET. This collaborative space offers valuable advice and peer feedback to enhance your online profile and professional presence. Join this drop-in workshop through Zoom.
URL:https://coe.northeastern.edu/event/linkedin-cv-resume-commlab-drop-in-hours/2025-07-15/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250716T130000
DTEND;TZID=America/New_York:20250716T140000
DTSTAMP:20260424T230045
CREATED:20250529T201710Z
LAST-MODIFIED:20250529T201710Z
UID:51081-1752670800-1752674400@coe.northeastern.edu
SUMMARY:Scientific Oral Communication : CommLab Drop-In Workshops
DESCRIPTION:The NU CommLab is hosting a weekly hybrid Scientific Oral Communication Drop-in practice for graduate students. Drop-in virtually or in-person any week to practice for your upcoming oral exams\, proposals\, thesis\, dissertation or talks. Receive and implement feedback on your verbal and non-verbal public speaking skills. Meet any Wednesday from 1-2pm in 306 Egan or on Zoom. Note on June 4th the workshop will be in 206 Egan.
URL:https://coe.northeastern.edu/event/scientific-oral-communication-commlab-drop-in-workshops/2025-07-16/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250717T120000
DTEND;TZID=America/New_York:20250717T140000
DTSTAMP:20260424T230045
CREATED:20250714T140901Z
LAST-MODIFIED:20250716T153549Z
UID:52563-1752753600-1752760800@coe.northeastern.edu
SUMMARY:ChE PhD Dissertation Defense: Yang Hu
DESCRIPTION:Name: Yang Hu \nTitle: Sex-Based Difference in Schwann Cell Migration in Response to Topography\, Laminin-derived Peptide and Transforming Growth Factor-β1 as in vitro Models for Peripheral Nerve Repair \nDate: 07/17/2025 \nTime: 12:00:00 PM \nCommittee Members:\nProf. Rebecca Willits (Advisor)\nProf. Matthew Becker\nProf. Ryan Koppes\nProf. Eno Ebong \nLocation: 220 Shillman \nAbstract:\nPeripheral nerve repair highly relies on Schwann cell migration within the nerve gap. Repairing a critical-sized nerve gap (~3-4 cm in humans) remains a significant challenge for satisfactory recover outcomes. Facilitating Schwann cell migration for accelerating nerve regeneration has attracted great research interest. This dissertation explores the individual and synergistic effects of different types of external cues: topography\, uniform and gradient of biochemical cues. \nFirst\, this dissertation found that female cells moved faster\, while male cells were more persistent on glass surfaces\, indicating an innate sex-based difference in motility responses. This difference was additionally regulated in both a sex- and diameter-dependent manner by three distinct fiber diameter (0.9\, 1.2 and 1.8 µm) provided by Dr. Becker’s lab (Duke University). The smaller fibers attenuated innate motility differences\, while they reappeared on the largest fiber. \nThe second part of this dissertation harnessed the finding that 1.2 µm fibers did not induce migration differences\, with YIGSR\, a peptide derived from laminin β1 chain\, which can facilitate Schwann cell proliferation and directionally guide cell migration. YIGSR-tethered fiber scaffolds in different profiles were characterized and provided (Dr. Becker’s lab) for conducting migration studies. We found that cells responded in both sex- and concentration-dependent manner to uniform concentrations. Directional cell migration only occurred at specific locations along the steepest gradient\, indicating a competing effect of contact guidance and tethered YIGSR. \nThe third part of this dissertation discovered the role of transforming growth factor-β1 (TGF-β1) in defined profiles on Schwann cell migration. We found that uniform TGF-β1 concentrations enhanced Schwann cell migration in a concentration-dependent manner\, while no directional migration was observed under TGF-β1 gradients. Understanding how TGF-β1 modulates Schwann cell migration provides insights for developing therapeutic strategies and biomaterials that seek to promote nerve regeneration.
URL:https://coe.northeastern.edu/event/che-phd-dissertation-defense-yang-hu/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250721T140000
DTEND;TZID=America/New_York:20250721T160000
DTSTAMP:20260424T230045
CREATED:20250714T140746Z
LAST-MODIFIED:20250714T140746Z
UID:52596-1753106400-1753113600@coe.northeastern.edu
SUMMARY:ChE PhD Dissertation Defense: William Doherty
DESCRIPTION:Name: William Doherty \nTitle: Stimulating Excitable Cells with Optosomes: Development of a Non-viral Cell Derived Vesicle Capable of Stimulating Excitable Cells in Response to Light Stimulus \nDate: 07/21/2025 \nTime: 2:00:00 PM \nCommittee Members:\nProf. Ryan Koppes (Advisor)\nProf. Abigail Koppes\nProf. Benjamin Woolston\nProf. Rebecca Shansky \nLocation: Shillman Hall 420 \nAbstract: \nFor years\, researchers have studied and developed neuromodulation techniques meant to stimulate and/or inhibit excitable cells both in research and clinical settings. A method to excite cells with light\, termed Optogenetics\, has been researched extensively since its discovery in the early 2000’s. A major constraint of Optogenetics is the expression of the necessary light-gated ion channels most often achieved using a viral vector. While this is not overly concerning in research settings\, clinical applications of optogenetics have been slow to develop as the use of viral vectors in humans presents challenges regarding safety. Additionally\, foreign opsin genes are believed to be a permanent addition to the transfected cells. \nThis dissertation aimed to develop Optosomes; a cell-derived vesicle containing excitatory opsin that couples with excitable cells via Gap-Junctions that conduct the stimulus current from the opsin into the cell. Initial production of Optosomes followed established protocols for producing Giant Plasma Membrane Vesicles (GPMVs) in which small volumes of cytoplasm are encapsulated in a piece of the cell’s plasma membrane. The number of GPMVs produced varied with pH\, cell confluency\, and base medium having a noticeable impact on the number of GPMVs generated. Optosome production required the creation of a stable cell line expressing Channelrhodopsin-2 (ChR2) and connexin-43 (Cx43) proteins required to form Gap-Junctions. Two separate transfections in the series generated a ChR2-Cx43 Hek293 cell line capable of producing Optosomes at a high concentration. Finally\, a mathematical model was built to simulate Optosome stimulation of excitable cells and how changes in the size of Optosomes and cells affect the strength of stimulus generated. The result of these simulations and attempts to stimulate neonatal Cardiomyocytes (CM) in vitro confirmed that the majority of Optosomes produced were too small to generate a stimulus capable of exciting CMs. Production of Optosomes with larger diameters or the use of a different strand of ChR2 is needed to increase the number of Optosomes able to stimulate CMs will be needed moving forward. \nThe results of this dissertation provide the foundation for developing Optosomes as an alternative approach to stimulating excitable cells with light. \n\nWilliam Doherty Northeastern University-Department of Chemical Engineering After spending nearly two years working on the development of a new automated Biomanufacturing system in the Love Lab\, Bill was accepted and enrolled in the PhD program for Chemical Engineering. After finding his home for the next 7 years in the Koppes Lab\, he got to work both on forming his thesis and integrating into the community at Northeastern. In pursuing his Ph. D\, he had started to appreciate how applying mathematical modeling techniques to biological systems offers a whole new perspective when trying to understand the complex innerworkings of the human body. It offered a nice juxtaposition to the time spent in lab running hands on experiments that are less about math and academic prowess and more about technique\, adaptability\, and problem solving in real time. Bill has sed the better part of his twenties working in Research and its why he was so eager to pursue a Ph D as he hopes to work his way into scientist positions overseeing research and development projects. Still residing in Boston\, he hopes to find a position in the New England Area after submitting his Dissertation; staying close to family and friends in the area.
URL:https://coe.northeastern.edu/event/che-phd-dissertation-defense-william-doherty/
LOCATION:420 Shillman Hall\, 360 Huntington Ave\, Boston\, MA\, 02115\, United States
GEO:42.3396156;-71.0886534
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=420 Shillman Hall 360 Huntington Ave Boston MA 02115 United States;X-APPLE-RADIUS=500;X-TITLE=360 Huntington Ave:geo:-71.0886534,42.3396156
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250722T090000
DTEND;TZID=America/New_York:20250722T110000
DTSTAMP:20260424T230045
CREATED:20250529T202417Z
LAST-MODIFIED:20250529T202417Z
UID:51025-1753174800-1753182000@coe.northeastern.edu
SUMMARY:Graduate Student Writing:  CommLab Drop-In Writing Hours
DESCRIPTION:Graduate students\, are you looking for a time for focused research writing?  Join the CommLab drop-in writing hours any Tuesday between 9 -11 am ET.  Drop in any Tuesday and stay for a short time or two hours.  A CommLab Fellow will be available to provide feedback on your writing.  We will be meeting virtually on Teams.
URL:https://coe.northeastern.edu/event/graduate-student-writing-commlab-drop-in-writing-hours/2025-07-22/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250722T100000
DTEND;TZID=America/New_York:20250722T120000
DTSTAMP:20260424T230045
CREATED:20250529T202133Z
LAST-MODIFIED:20250529T202133Z
UID:51064-1753178400-1753185600@coe.northeastern.edu
SUMMARY:Graduate Student Proposal/Fellowship Writing Hours: CommLab Drop-In Hours
DESCRIPTION:Graduate students\, are you looking for support in writing your research or fellowship proposal?  Join the CommLab virtual drop-in writing hours any Tuesday between 10 am -12 pm ET and stay for a short time or the whole two hours.  A CommLab Fellow will be available to help you set writing goals and provide feedback on your writing.  Join this drop-in workshop through Zoom.
URL:https://coe.northeastern.edu/event/graduate-student-proposal-fellowship-writing-hours-commlab-drop-in-hours/2025-07-22/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250722T110000
DTEND;TZID=America/New_York:20250722T120000
DTSTAMP:20260424T230045
CREATED:20250529T202325Z
LAST-MODIFIED:20250529T202325Z
UID:52661-1753182000-1753185600@coe.northeastern.edu
SUMMARY:LinkedIn\, CV\, Resume: CommLab Drop-In Hours
DESCRIPTION:Graduate students\, do you need to increase your on-line presence or update your CV or Resume?  Join the CommLab’s LinkedIn\, CV\, and Resume drop-in workshops every other Tuesday from 11 pm to 12 pm ET. This collaborative space offers valuable advice and peer feedback to enhance your online profile and professional presence. Join this drop-in workshop through Zoom.
URL:https://coe.northeastern.edu/event/linkedin-cv-resume-commlab-drop-in-hours/2025-07-22/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250723T130000
DTEND;TZID=America/New_York:20250723T140000
DTSTAMP:20260424T230045
CREATED:20250529T201711Z
LAST-MODIFIED:20250529T201711Z
UID:51082-1753275600-1753279200@coe.northeastern.edu
SUMMARY:Scientific Oral Communication : CommLab Drop-In Workshops
DESCRIPTION:The NU CommLab is hosting a weekly hybrid Scientific Oral Communication Drop-in practice for graduate students. Drop-in virtually or in-person any week to practice for your upcoming oral exams\, proposals\, thesis\, dissertation or talks. Receive and implement feedback on your verbal and non-verbal public speaking skills. Meet any Wednesday from 1-2pm in 306 Egan or on Zoom. Note on June 4th the workshop will be in 206 Egan.
URL:https://coe.northeastern.edu/event/scientific-oral-communication-commlab-drop-in-workshops/2025-07-23/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250724T100000
DTEND;TZID=America/New_York:20250724T120000
DTSTAMP:20260424T230045
CREATED:20250723T173250Z
LAST-MODIFIED:20250723T173250Z
UID:52650-1753351200-1753358400@coe.northeastern.edu
SUMMARY:ChE MS Thesis Defense: Julie Penn
DESCRIPTION:Name: Julie Penn \nTitle: Development\, Optimization\, and Evaluation of SWIR Emitting QD Imaging Tools \nDate: 07/24/2025 \nTime: 10:00:00 AM \nCommittee Members:\nProf. Allison Dennis (Advisor)\nProf. Bryan James\nProf. Ryan Koppes\nProf. Bryan Spring \nLocation: Shillman Hall 315 \nAbstract:\nShelf-stable fluorescent imaging references are commercially available. However\, they are only available in the visible range (380-700 nm) and the near infrared I range (NIR I\, 700-900 nm). These references are not available within the shortwave infrared range (SWIR\, 1000-1700 nm). SWIR emitting semiconductor quantum dots (QDs) have a tunable emission spectrum and are used in a range of SWIR imaging applications. In addition to their adjustable spectrum\, QDs\, particularly lead sulfide/cadmium sulfide (PbS/CdS) core/shell QDs\, are incredibly photostable. This quality makes them optimal fluorophores for SWIR fluorescent imaging references. When the PbS/CdS QDs are embedded in epoxy\, the QDs are contained in a permanent\, shelf stable\, oxygen-free environment. Thus\, a SWIR fluorescent imaging sample is created. By changing the form factor of these objects\, researchers can investigate SWIR imaging at depth\, multiplexed imaging for spectral demixing using a baseline fluorescence intensity measurement. The performance of each tool was evaluated based on the photostability\, the florescence intensity at depth\, and the emission spectrum of the QDs contained within each type of florescence imaging tool. \n\nJulie Penn is currently a 2nd year master’s student studying chemical engineering at Northeastern University. She is studying under the guidance of Dr. Allison Dennis\, and her thesis is on Development\, Optimization\, and Evaluation of SWIR Emitting QD Imaging Tools. Outside of the laboratory\, Julie is a proud and active member of the Boston section of Society of Women Engineers. In 2019 Julie graduated from Wentworth Institute of Technology with a degree in mechanical Engineering with a concentration in chemistry and began working at 908 Devices\, a mass spectrometry manufacturer based in Boston\, MA. As a member of the Customer Experience Team\, Julie supported the R&D\, manufacturing\, quality\, and sales departments\, but most importantly the customers by repairing internal and customer-returned mass spectrometers\, answering technical support phone calls\, and traveling around the world to train users on their equipment. She was awarded the 2022 Customer Service Person of the Year for her outstanding support of the 908 Devices sales team. Upon the completion of her degree\, Julie is looking to rejoin the workforce as a materials engineer. She is very excited to start this next journey of her career.
URL:https://coe.northeastern.edu/event/che-ms-thesis-defense-julie-penn/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250725T160000
DTEND;TZID=America/New_York:20250725T180000
DTSTAMP:20260424T230045
CREATED:20250723T173800Z
LAST-MODIFIED:20250723T173800Z
UID:52728-1753459200-1753466400@coe.northeastern.edu
SUMMARY:SUNY Buffalo Graduate School Fair
DESCRIPTION:Join COE Graduate Admissions at the 2025 SUNY Buffalo Graduate School Fair in Buffalo\, New York! Ask your questions about our graduate engineering programs across the U.S. and Canada during the fair on July 25th from 4pm-6pm. We look forward to meeting you there!
URL:https://coe.northeastern.edu/event/suny-buffalo-graduate-school-fair/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250729T090000
DTEND;TZID=America/New_York:20250729T110000
DTSTAMP:20260424T230045
CREATED:20250529T202417Z
LAST-MODIFIED:20250529T202417Z
UID:51026-1753779600-1753786800@coe.northeastern.edu
SUMMARY:Graduate Student Writing:  CommLab Drop-In Writing Hours
DESCRIPTION:Graduate students\, are you looking for a time for focused research writing?  Join the CommLab drop-in writing hours any Tuesday between 9 -11 am ET.  Drop in any Tuesday and stay for a short time or two hours.  A CommLab Fellow will be available to provide feedback on your writing.  We will be meeting virtually on Teams.
URL:https://coe.northeastern.edu/event/graduate-student-writing-commlab-drop-in-writing-hours/2025-07-29/
END:VEVENT
END:VCALENDAR