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Sidi A. Bencherif

Assistant Professor,  Chemical Engineering
Affiliated Faculty,  Bioengineering



  • 336 Mugar
  • 617.373.7103


  • 111 Mugar

Research Focus

polymer chemistry and engineering; biomaterials; biomedical engineering; drug delivery; tissue engineering; regenerative medicine; immunotherapy; immunoengineering; vaccines


Joined the Chemical Engineering Department in Fall 2016.


  • 2009 PhD in Chemistry, Carnegie Mellon University
  • 2009 MS in Polymer Science, Carnegie Mellon University
  • 1999 B.S. in Physics and Chemistry from University of Montpellier II, France

Professional Affiliations

  • American Association of Immunologists (AAI)
  • American Chemical Society (ACS)
  • Materials Research Society (MRS)
  • Scientific Research Society (Sigma Xi)
  • Society for Biomaterials (SFB)

Research Overview

polymer chemistry and engineering; biomaterials; biomedical engineering; drug delivery; tissue engineering; regenerative medicine; immunotherapy; immunoengineering; vaccines

Selected Research Projects

  • Biomaterials for Wound Healing and Diabetic Ulcer Treatment
    • Co-Investigator, King Abdulaziz University
  • Cryogel-Supported Liver-on-a-Chip for Ex-vivo Hepatotoxicity and Anticancer Drug Screening
    • Principal Investigator, Burroughs-Wellcome Fund
  • Modulating Local Tumor Hypoxia using Cryogel Scaffolds to Regulate Dendritic Cell Function and Activity
    • Principal Investigator, National Science Foundation

College Research Initiatives

Selected Publications

  • A. Memic, T. Colombani, M. Rezaeeyazdi, L. Eggermont, J. Steingold, Z. Rogers, K.J. Navare, H.S. Mohammed, M. Sitkovsky, S.A. Bencherif, Latest Advances in Cryogel Technology for Biomedical Applications, Advanced Therapeutics, 2019, 1800114
  • A. Memic, T. Abudula, H. Mohammed, K.J. Navare, T. Colombani, S.A. Bencherif, Latest Progress in Electrospun Nanofibers for Wound Healing Applications, ACS Applied Bio Materials, 2, 2019, 952-969
  • M. Rezaeeyazdi, T. Colombani, A. Memic, S.A. Bencherif, Injectable Hyaluronic Acid-Co-Gelatin Cryogels for Tissue Engineering Applications, Materials, 2018, 11, 1374
  • S.A. Bencherif, R.W. Sands, O. Ali, S.A. Lewin, A. Li, T. Braschler, T. Shih, D. Bhatta, G. Dranoff, D.J. Mooney, Injectable Scaffold-Based Whole Tumor Cell Vaccines, Nature Communications, 6, 2015, 7556
  • O. Chaudhuri, L. Gu, D. Klumpers, M. Darnell, S.A. Bencherif, J.C. Weaver, N. Huebsch, D.J Mooney, Substrate Stress Relaxation Regulates Cell Spreading, Nature Communications, 6, 2015, 6365
Sidi A. Bencherif, Zach Rogers, James Sherley


Sep 14, 2020

Bencherif Lab Receives NSF I-Corps Teams Award

The Bencherif lab received a $50K NSF award for “Oxygen-controlling Cryogels for Cell Culture Applications” to participate in the national NSF Innovation Corps Teams program.


May 18, 2020

Bencherif’s Research Published and Featured on the Cover of Macromolecular Materials and Engineering

ChE Assistant Professor Sidi A. Bencherif’s research on “Effect of Polymer Concentration on Autoclaved Cryogel Properties” was featured on the back cover page of the May issue of Macromolecular Materials and Engineering.


Mar 30, 2020

Bencherif’s Research Featured on the Front Cover of Trends in Biotechnology

ChE Professor Sidi A. Bencherif’s research on “Injectable Cryogels for Biomedical Applications” featured on the front cover page of the April issue of Trends in Biotechnology.

gapfund logo


Jan 30, 2020

Eight COE Projects Selected for GapFund360

Northeastern’s GapFund360 program helps Northeastern’s researchers bridge the gap between promising lab results and demonstrating a commercially viable prototype. Awards range from $50K -$100K. Nine projects were selected from a pool of 39 applications from across the university; COE contributed 25 of the applications and seven projects were selected for funding. Congratulations to the following COE researchers whose projects were selected for Phase I or Phase II GapFund360 funding: ChE Assistant Professor Sidi Bencherif, MIE Assistant Professor Safa Jamali, ECE Assistant Professor Sarah Ostadabbas, ChE/COS Associate Professor Carolyn Lee-Parsons, ECE Professor Tommaso Melodia, ECE Associate Research Scientist Salvatore D’Oro, ECE Associate Professor Kaushik Chowdhury, ECE Principal Research Scientist Yousof Naderi, ECE Postdoc Ufuk Muncuk, ECE Professor Vincent Harris, ECE Associate Research Scientist Parisa Andalib, ECE Associate Professor Matteo Rinaldi, and ECE Research Assistant Professor Zhenyun Qian.


Dec 16, 2019

Bencherif Lab Receives ACORN Award

Chemical Engineering Assistant Professor Sidi A. Bencherif recently received a 2020 ACORN Innovation Award from The Massachusetts Technology Transfer Center for his project entitled “Hypoxia-inducing cryogels as a fast and inexpensive technology for hypoxic cell culture conditions”.



Dec 13, 2019

Compressible Cryogels to Target Diseased Cells

ChE Assistant Professor Sidi Bencherif created a sponge-like gel that can be injected under the skin to provide medication or target certain immune cells.


Dec 12, 2019

James Sinoimeri to Present at International Exchange with German Chemical Society (GDCh)

James Sinoimeri, E’21, will be presenting his work from ChE Assistant Professor Sidi A. Bencherif’s lab at a highly selective international exchange program of the Gesellschaft Deutscher Chemiker (German Chemical Society, GDCh).

Spotlight Story

Nov 21, 2019

Taking Research to the NSF I-Corps ‘Shark Tank’

Cell culture research—defined as the process by which cells are grown in conditions like those in the body—is one of the most useful tools at scientists’ disposal. In several research areas, it is desirable to grow cells in low oxygen conditions or hypoxia. However, the cost of hypoxic cell culture is far too high, discouraging […]


Nov 21, 2019

ChE Students Chris Meehan and Michael Parrish win Northeastern’s PEAK Ascent Award

ChE undergraduate student Chris Meehan and BioE undergraduate student Michael Parrish were awarded Northeastern’s PEAK Ascent awards.

ChE Assistant Professor Sidi Bencherif on stage giving a talk at the 2019 World Young Scientist Summit in Wenzhou, China (Oct. 26-27).


Nov 21, 2019

Bencherif Delivered Keynote Lecture at the 2019 World Young Scientist Summit

ChE Assistant Professor Sidi Bencherif was invited to give a keynote lecture at the symposium: Opportunities and Challenges in Biomaterials Research in Wenzhou, China

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