Sidi A. Bencherif

Assistant Professor,  Chemical Engineering
Affiliated Faculty,  Bioengineering



  • 336 Mugar
  • 617.373.7103


  • 111 Mugar

Research Focus

polymer chemistry and engineering; biomaterials; biomedical engineering; drug delivery; tissue engineering; regenerative medicine; immunotherapy; immunoengineering; vaccines


Joined the Chemical Engineering Department in Fall 2016.


  • 2009 PhD in Chemistry, Carnegie Mellon University
  • 2009 MS in Polymer Science, Carnegie Mellon University
  • 1999 B.S. in Physics and Chemistry from University of Montpellier II, France

Professional Affiliations

  • American Association of Immunologists (AAI)
  • American Chemical Society (ACS)
  • Materials Research Society (MRS)
  • Scientific Research Society (Sigma Xi)
  • Society for Biomaterials (SFB)

Research Overview

polymer chemistry and engineering; biomaterials; biomedical engineering; drug delivery; tissue engineering; regenerative medicine; immunotherapy; immunoengineering; vaccines

Selected Research Projects

  • Biomaterials for Wound Healing and Diabetic Ulcer Treatment
    • Co-Investigator, King Abdulaziz University
  • Cryogel-Supported Liver-on-a-Chip for Ex-vivo Hepatotoxicity and Anticancer Drug Screening
    • Principal Investigator, Burroughs-Wellcome Fund
  • Modulating Local Tumor Hypoxia using Cryogel Scaffolds to Regulate Dendritic Cell Function and Activity
    • Principal Investigator, National Science Foundation

College Research Initiatives

Selected Publications

  • A. Memic, T. Colombani, M. Rezaeeyazdi, L. Eggermont, J. Steingold, Z. Rogers, K.J. Navare, H.S. Mohammed, M. Sitkovsky, S.A. Bencherif, Latest Advances in Cryogel Technology for Biomedical Applications, Advanced Therapeutics, 2019, 1800114
  • A. Memic, T. Abudula, H. Mohammed, K.J. Navare, T. Colombani, S.A. Bencherif, Latest Progress in Electrospun Nanofibers for Wound Healing Applications, ACS Applied Bio Materials, 2, 2019, 952-969
  • M. Rezaeeyazdi, T. Colombani, A. Memic, S.A. Bencherif, Injectable Hyaluronic Acid-Co-Gelatin Cryogels for Tissue Engineering Applications, Materials, 2018, 11, 1374
  • S.A. Bencherif, R.W. Sands, O. Ali, S.A. Lewin, A. Li, T. Braschler, T. Shih, D. Bhatta, G. Dranoff, D.J. Mooney, Injectable Scaffold-Based Whole Tumor Cell Vaccines, Nature Communications, 6, 2015, 7556
  • O. Chaudhuri, L. Gu, D. Klumpers, M. Darnell, S.A. Bencherif, J.C. Weaver, N. Huebsch, D.J Mooney, Substrate Stress Relaxation Regulates Cell Spreading, Nature Communications, 6, 2015, 6365


Jan 11, 2021

Student Zach Rogers wins Second Alpha Fund Prototype Grant

Zach Rogers, a Chemical Engineering PhD student in the Bencherif Lab, was recently awarded the Alpha Fund Prototype Grant for his proposal, “Hypoxia-inducing cryogels for two-dimensional cell culture”.


Jan 07, 2021

Bencherif Named 2021 BMES CMBE Rising Star

Chemical Engineering Assistant Professor Sidi A. Bencherif has been named one of the 2021 Rising Stars by the Cellular and Molecular Bioengineering (CMBE) Special Interest Group (SIG) within the Biomedical Engineering Society (BMES).


Oct 30, 2020

James Sinoimeri Selected as Future Leader in Chemical Engineering

Fifth-year Chemical Engineering student James Sinoimeri (E’21) was selected for the Future Leaders in Chemical Engineering Symposium organized by North Carolina State University.


Oct 30, 2020

Bencherif Nominated as Biomaterials Science Emerging Investigator 2021

ChE Assistant Professor Sidi A. Bencherif and his team published their work on “Engineering a macroporous fibrin-based sequential interpenetrating polymer network for dermal tissue engineering” in Biomaterials Science as part of their Biomaterials Science Emerging Investigators 2021.


Sep 16, 2020

Koppes and Bencherif Published in Bioelectricity

ChE Assistant Professors Ryan Koppes and Sidi A. Bencherif were published in Bioelectricity for their research on “Electroconductive Hydrogels for Tissue Engineering: Current Status and Future Perspectives.”

Sidi A. Bencherif, Zach Rogers, James Sherley


Sep 14, 2020

Bencherif Lab Receives NSF I-Corps Teams Award

The Bencherif lab received a $50K NSF award for “Oxygen-controlling Cryogels for Cell Culture Applications” to participate in the national NSF Innovation Corps Teams program.


May 18, 2020

Bencherif’s Research Published and Featured on the Cover of Macromolecular Materials and Engineering

ChE Assistant Professor Sidi A. Bencherif’s research on “Effect of Polymer Concentration on Autoclaved Cryogel Properties” was featured on the back cover page of the May issue of Macromolecular Materials and Engineering.


Mar 30, 2020

Bencherif’s Research Featured on the Front Cover of Trends in Biotechnology

ChE Professor Sidi A. Bencherif’s research on “Injectable Cryogels for Biomedical Applications” featured on the front cover page of the April issue of Trends in Biotechnology.

gapfund logo


Jan 30, 2020

Eight COE Projects Selected for GapFund360

Northeastern’s GapFund360 program helps Northeastern’s researchers bridge the gap between promising lab results and demonstrating a commercially viable prototype. Awards range from $50K -$100K. Nine projects were selected from a pool of 39 applications from across the university; COE contributed 25 of the applications and seven projects were selected for funding. Congratulations to the following COE researchers whose projects were selected for Phase I or Phase II GapFund360 funding: ChE Assistant Professor Sidi Bencherif, MIE Assistant Professor Safa Jamali, ECE Assistant Professor Sarah Ostadabbas, ChE/COS Associate Professor Carolyn Lee-Parsons, ECE Professor Tommaso Melodia, ECE Associate Research Scientist Salvatore D’Oro, ECE Associate Professor Kaushik Chowdhury, ECE Principal Research Scientist Yousof Naderi, ECE Postdoc Ufuk Muncuk, ECE Professor Vincent Harris, ECE Associate Research Scientist Parisa Andalib, ECE Associate Professor Matteo Rinaldi, and ECE Research Assistant Professor Zhenyun Qian.


Dec 16, 2019

Bencherif Lab Receives ACORN Award

Chemical Engineering Assistant Professor Sidi A. Bencherif recently received a 2020 ACORN Innovation Award from The Massachusetts Technology Transfer Center for his project entitled “Hypoxia-inducing cryogels as a fast and inexpensive technology for hypoxic cell culture conditions”.

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