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Jiahe Li

Assistant Professor,  Bioengineering



  • 225 ISEC
  • 617.373.3233

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Research Focus

Oral vaccine, host and oral microbiome interactions, microbiome engineering, and protein engineering-based cancer immunotherapy


  • Post-doc, David Koch Institute of Integrative Cancer, Massachusetts Institute of Technology
  • PhD, Biomedical Engineering, Cornell University
  • BS, Biochemistry, China Agricultural University

Honors & Awards

  • 2016 David Koch Institute Quinquennial Postdoctoral Fellowship
  • 2018 Peer Reviewed Medical Research Program Discovery Award, Department of Defense

Professional Affiliations

  • Biomedical Engineering Society
  • American Institute of Chemical Engineers
  • American Chemical Society

Research Overview

Oral vaccine, host and oral microbiome interactions, microbiome engineering, and protein engineering-based cancer immunotherapy

College Research Initiatives

Department Research Areas

Selected Publications

After transitioning to the PI in 2019

Before transitioning to the PI in 2019

  • Ludwicki MB, Li J, Stephens EA, Roberts RW, Koide S, Hammond PT, DeLisa MP. Broad-Spectrum Proteome Editing with an Engineered Bacterial Ubiquitin Ligase Mimic. ACS Cent Sci. 2019 May 22;5(5):852-866.
  • Li J, He Y, Wang W, Wu C, Hong C, Hammond PT. Polyamine-Mediated Stoichiometric Assembly of Ribonucleoproteins for Enhanced mRNA Delivery. Angewandte Chemie (International ed. in English). 2017; 56(44):13709-13712.
  • Li J, Wang W, He Y, Li Y, Yan EZ, Zhang K, Irvine DJ, Hammond PT. Structurally Programmed Assembly of Translation Initiation Nanoplex for Superior mRNA Delivery. ACS Nano. 2017 Mar 28;11(3):2531-2544.


Oct 16, 2020

COE Faculty Awarded Seed Funding in Collaboration with University of Maine

BioE Assistant Professors Jiahe Li and Mingyang Lu, ECE Professor & Chair Srinivas Tadigadapa, ECE Assistant Professors Sarah Ostadabbas and Xue “Shelley” Lin, and ECE Associate Research Scientist Ataur Katebi were among the faculty chosen for five competitive collaborative research projects with the University of Maine in the areas of artificial intelligence, earth and climate sciences, health and life sciences, manufacturing, and marine sciences.


Oct 01, 2020

Assuring that Self-Driving Cars are Accessible to Those with Disabilities

ECE Assistant Professor Xue “Shelley” Lin is working with the algorithms in self-driving vehicles to ensure that they will be accessible to those with disabilities.


Apr 11, 2020

FY21 TIER 1 Award Recipients

Congratulations to the 19 COE faculty and affiliates who were recipients of FY21 TIER 1 Interdisciplinary Research Seed Grants for 13 different projects.

Portraits of Bajpayee and Li


Aug 20, 2019

Bajpayee Awarded NIH Trailblazer R21 Grant

BioE Assistant Professor Ambika Bajpayee(PI) and Jiahe Li (co-PI) were awarded a $628K NIH Trailblazer grant from the National Institute of Biomedical Imaging and Bioengineering for “Anti-Catabolic Drug Anchored Cationic Exosomes For Cartilage Targeting And Repair”.


Apr 09, 2019

FY20 TIER 1 Award Recipients

25 COE faculty and affiliates were recipients of FY20 TIER 1 Interdisciplinary Research Seed Grants for 18 different projects representing up to $900K dollars of investment in research.


Jan 04, 2019

New Faculty Spotlight: Jiahe Li

Jiahe Li joins the Bioengineering department in January 2019 as an Assistant Professor.

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