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EXPLORE NORTHEASTERN

Harikrishnan Parameswaran

Assistant Professor,  Bioengineering

Contact

Office

  • 617.373.7049

Research Focus

Mechanobiology of the smooth muscle, Mechanisms of force transmission in multicellular ensembles, Methods for targeting extracellular matrix for asthma therapy

About

Joined the Bioengineering department in January 2017.

Education

  • PhD, Boston University, 2009

Research Overview

Mechanobiology of the smooth muscle, Mechanisms of force transmission in multicellular ensembles, Methods for targeting extracellular matrix for asthma therapy

Selected Publications

  • S.M. Cloonan, K. Glass, A.R. Bhashyam, M.E. Laucho-Contreras, M. Cervo, M.A. Pabon, C. Konrad, F. Polverino, K. Miziumura, M. Ghosh, H. Parameswaran, N.M. Williams, K.T. Rooney, Z.H. Chen, M.P. Goldklang, G. Yuan, S.C. Moore, D.L. Demeo, T.A. Rouault, J.M. D’Armiento, E.A. Schon, G. Manfredi, J. Quackenbush, A. Mahmood, E.K. Silverman, C.A. Owen, A.M. Choi, Mitochondrial Iron Chelation Ameliorates Cigarette Smoke-Induced Bronchitis and Emphysema in Mice, Nature Medicine 22,  2016, 163-174
  • B. Suki, H. Parameswaran, J. Imsirovic, E.B. Suki, Regulatory Roles of Fluctuation-Driven Mechanotransduction in Cell Function, Physiology, 31(5), 2016, 346-358
  • E.B.Suki, J. Imsirovic, H. Parameswaran, T. Wellman, N Martinez, P.G. Allen, U. Frey, B. Suki, Fluctuation-Driven Mechanotransduction Regulates Mitochondrial-Network Structure and Function, Nature Materials, 14, 2015, 1049-1057
  • B. Suki, H. Parameswaran, Computational Modeling Helps Uncover Mechanisms Related to the Progression of Emphysema, Drug Discovery Today, 70(27-28), 2014, 4245-4249
  • H. Parameswaran, K.R. Lutchen, B. Suki, A Computational Model of the Response of Adherent Cells to Stretch and Changes in Substrate Stiffness, Journal of Applied Physiology 116(7), 2014, 825-834
  • S.R. Polio, H. Parameswaran, E.P. Canovic, D. Stamenovic, M.L. Smith, Topographical Control of Multiple Cell Adhesion Molecules for Traction Force Microscopy, Integrative Biology, 6(3), 2014, 357-365

Faculty

Apr 09, 2019

FY20 TIER 1 Award Recipients

25 COE faculty and affiliates were recipients of FY20 TIER 1 Interdisciplinary Research Seed Grants for 18 different projects representing up to $900K dollars of investment in research.

Faculty

Jan 20, 2017

New Faculty Spotlight: Harikrishnan Parameswaran

Harikrishnan Parameswaran joins the Bioengineering department in January 2017 as an Assistant Professor.

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