Harikrishnan Parameswaran
Assistant Professor,
Bioengineering
Contact
- h.parameswaran@northeastern.edu
- 219 ISEC
360 Huntington Avenue
Boston, Massachusetts
Office
- 617.373.7049
Research Focus
Mechanobiology of the smooth muscle, Mechanisms of force transmission in multicellular ensembles, Methods for targeting extracellular matrix for asthma therapy
About
Joined the Bioengineering department in January 2017.
Education
- PhD, Boston University, 2009
Research Overview
Mechanobiology of the smooth muscle, Mechanisms of force transmission in multicellular ensembles, Methods for targeting extracellular matrix for asthma therapy
Department Research Areas
Selected Publications
- S.M. Cloonan, K. Glass, A.R. Bhashyam, M.E. Laucho-Contreras, M. Cervo, M.A. Pabon, C. Konrad, F. Polverino, K. Miziumura, M. Ghosh, H. Parameswaran, N.M. Williams, K.T. Rooney, Z.H. Chen, M.P. Goldklang, G. Yuan, S.C. Moore, D.L. Demeo, T.A. Rouault, J.M. D’Armiento, E.A. Schon, G. Manfredi, J. Quackenbush, A. Mahmood, E.K. Silverman, C.A. Owen, A.M. Choi, Mitochondrial Iron Chelation Ameliorates Cigarette Smoke-Induced Bronchitis and Emphysema in Mice, Nature Medicine 22, 2016, 163-174
- B. Suki, H. Parameswaran, J. Imsirovic, E.B. Suki, Regulatory Roles of Fluctuation-Driven Mechanotransduction in Cell Function, Physiology, 31(5), 2016, 346-358
- E.B.Suki, J. Imsirovic, H. Parameswaran, T. Wellman, N Martinez, P.G. Allen, U. Frey, B. Suki, Fluctuation-Driven Mechanotransduction Regulates Mitochondrial-Network Structure and Function, Nature Materials, 14, 2015, 1049-1057
- B. Suki, H. Parameswaran, Computational Modeling Helps Uncover Mechanisms Related to the Progression of Emphysema, Drug Discovery Today, 70(27-28), 2014, 4245-4249
- H. Parameswaran, K.R. Lutchen, B. Suki, A Computational Model of the Response of Adherent Cells to Stretch and Changes in Substrate Stiffness, Journal of Applied Physiology 116(7), 2014, 825-834
- S.R. Polio, H. Parameswaran, E.P. Canovic, D. Stamenovic, M.L. Smith, Topographical Control of Multiple Cell Adhesion Molecules for Traction Force Microscopy, Integrative Biology, 6(3), 2014, 357-365
Aug 17, 2020
Research on Extracellular Matrix Making Waves for Asthma Therapy
BioE Assistant Professor Harikrishnan Parameswaran’s research on “Intercellular communication controls agonist-induced calcium oscillations independently of gap junctions in smooth muscle cells” was published in Science Advances.
Apr 09, 2019
FY20 TIER 1 Award Recipients
25 COE faculty and affiliates were recipients of FY20 TIER 1 Interdisciplinary Research Seed Grants for 18 different projects representing up to $900K dollars of investment in research.
Jan 20, 2017
New Faculty Spotlight: Harikrishnan Parameswaran
Harikrishnan Parameswaran joins the Bioengineering department in January 2017 as an Assistant Professor.