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EXPLORE NORTHEASTERN

Edgar D. Goluch

Associate Professor,  Chemical Engineering
Affiliated Faculty,  Bioengineering
Affiliated Faculty,  Civil and Environmental Engineering
Affiliated Faculty,  Biology

Contact

Social Media

Office

  • 253 Egan
  • 617.373.3500

Lab

  • 255 Egan
  • 617.373.3969

Research Focus

detection of biomolecules at the nanoscale in micro and nanofluidic channels; biophysics; micro and systems biology; environmental sensing; analytical instrumentation

About

Joined the Chemical Engineering Department in Fall 2010.

The primary focus of our research is the development of detection strategies that are tailored for the micro and nanoscale, with emphasis on biological systems. We work at size scales ranging from single molecules to single cells. Applications of this research range from personalized medicine to environmental monitoring. We also have expertise in electrochemistry and fabrication of integrated microfluidic systems.

Education

  • BS (Chemical Engineering) University of Illinois at Urbana-Champaign, 2003
  • MS (Mechanical Engineering) University of Illinois at Urbana-Champaign, 2005
  • PhD (Bioengineering) University of Illinois at Urbana-Champaign, 2007
  • N.S.F. Postdoctoral Fellow Delft University of Technology, NL, 2008-2010

Honors & Awards

  • 2017 Outstanding Translational Research Award

Research Overview

detection of biomolecules at the nanoscale in micro and nanofluidic channels; biophysics; micro and systems biology; environmental sensing; analytical instrumentation

Selected Research Projects

  • Point-of-Care Test for Identifying Gram Negative Urinary Tract Infections in Companion Animals
    • – Principal Investigator, National Science Foundation

Selected Publications

  • M.K. Kimani, J. Mwagi, E.D. Goluch, Bacterial Sample Concentration and Culture Monitoring using a PEG-Based Osmotic System with Inline Impedance and Voltammetry Measurements, Journal of Analysis and Testing, 3(2), 2019, 166-174
  • M.K. Kimani, R. Loo, E.D. Goluch, Biosample Concentration Using Microscale Forward Osmosis with Electrochemical Monitoring, Analytical Chemistry, 91, 2019, 7487-7494
  • P.J. Buch, Y. Chai, E.D. Goluch, Treating Polymicrobial Infections in Chronic Diabetic Wounds, Clinical Microbiology Reviews, 32(2), 2019, e00091-18
  • J. Sun, N. Tandogan, A.Z. Gu, S. Müftü, E.D. Goluch, K.T. Wan, Quantification of Colloidal Filtration of Polystyrene Micro-Particles on Glass Substrate Using a Microfluidic Device, Colloids and Surfaces B: Biointerfaces 165, 2018, 381-387
  • C.R. Santiveri, H.J. Sismaet, M. Kimani, E.D. Goluch, Electrochemical Detection of Pseudomonas Aeruginosa in Polymicrobial Environments, ChemistrySelect, 3(11), 2018 2926-2930
  • H.J. Sismaet, E.D. Goluch, Electrochemical Probes of Microbial Community Behavior, Annual Review of Analytical Chemistry, 2018
  • P.N. Abadian, P.J. Buch, E.D. Goluch, J. Li, Z. Zhang, Real-Time Monitoring of Urinary Encrustation Using a Quartz Crystal Microbalance, Analytical Chemistry, 90(3), 2018, 1531-1535

Faculty

Apr 21, 2020

Goluch Awarded Patent for Nanofluidic Device

ChE Associate Professor Edgar Goluch was awarded a patent for “Nanofluidic device for isolating, growing, and characterizing microbial cells”.

Faculty

Jan 09, 2020

Ed Goluch, “Diagnosis in Minutes”

ChE Associate Professor Edgar Goluch was featured in the Angel Invest Boston podcast “Diagnosis in Minutes“.

Faculty

Jul 10, 2019

Prof. Ed Goluch to give invited Plenary Talk at AIChe Annual Meeting this Fall

ChE Associate Professor Ed Goluch has been invited to give a Plenary Talk at the 2019 American Institute of Chemical Engineers (AIChE) conference in November on “Electrochemical Sensors for Multiplexed Infection Detection and Monitoring”.

Faculty

Jun 20, 2019

Goluch Awarded Patent for Rapid Bacterial Infection Diagnosis System

ChE Associate Professor Edgar Goluch was awarded a patent for creating a "Diagnostic system and process for rapid bacterial infection diagnosis". Abstract Source: USPTO Methods and devices for monitoring the viability of a biofilm comprising Pseudomonas Aeruginosa bacteria are provided by detecting pyocyanin. The invention relates to electrochemical methods and devices that offer a simple […]

Faculty

Feb 12, 2019

ChE Student's Paper on Front Page of CMR Website

Chemical Engineering PhD student Pranali Buch, advised by Professor Edgar Goluch, recently had her review paper “Treating Polymicrobial Infections in Chronic Diabetic Wounds” published in Clinical Microbiology Reviews.

Faculty

Oct 19, 2018

Quickly Diagnosing Infections Leads to Faster Treatments

ChE Associate Professor Edgar Goluch created the company QSM Diagnostics to help diagnose bacterial infections in animals quickly which would allow for faster treatments.

Graduate

Sep 21, 2018

NU ChE Graduate Student Publication in Collaboration with Wyss Institute/HMS

Research Scientist at the Wyss Institute and current ChE graduate student Daniel Wiegand’s research was featured in the ACS Synthetic Biology article “Establishing a Cell-Free Vibrio natriegens Expression System” for using super fold GFP as a read-out for tweaking a multitude of parameters in order to retain sustained protein expression in the cell-free reaction over a long period of time.

Faculty

Nov 01, 2017

Researcher and Entrepreneur

ChE Associate Professor Ed Goluch was featured in the Northeastern Magazine’s article “Faster, Cheaper, Better” for taking an idea of an early infection detection system and bringing it to market. His company, QSM Diagnostics, is developing a medical device that will detect bacterial infections in less than five minutes compared to the current three days. […]

Faculty

Oct 24, 2017

Prof. Goluch gives talk at 3rd Annual Single Cell Analysis USA Congress

ChE Associate Professor Ed Goluch gave a talk at the Third Annual Single Cell Analysis USA Congress in Boston on “Isolating Bacterial Cells and Measuring Metabolites Using Sub-Microfluidic Systems,” which discusses the unique challenges of bacterial cell analysis at the single cell level given their small size and motility.

Faculty

May 03, 2017

Faculty and Staff Awards 2017

Congratulations to all the winners of the faculty and staff awards, and to everyone for their hard work and dedication during the 2016-2017 academic school year. Faculty Fellow Edward Beighley, CEE Yun Raymond Fu, ECE Tommaso Melodia, ECE Rising Star Staff Award Erin Schnepp, Undergraduate Academic Advising Carolina Venegas-Martinez, CEE Outstanding Teachers of First Year […]

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