Edgar D. Goluch
Associate Professor, Chemical Engineering
Affiliated Faculty, Civil and Environmental Engineering
Affiliated Faculty, Biology
Office
- 253 Egan
- 617.373.3500
Lab
- 255 Egan
- 617.373.3969
Research Focus
Detection of biomolecules at the nanoscale in micro and nanofluidic channels; biophysics; micro and systems biology; environmental sensing; analytical instrumentation
About
Joined the Chemical Engineering Department in Fall 2010.
The primary focus of our research is the development of detection strategies that are tailored for the micro and nanoscale, with emphasis on biological systems. We work at size scales ranging from single molecules to single cells. Applications of this research range from personalized medicine to environmental monitoring. We also have expertise in electrochemistry and fabrication of integrated microfluidic systems.
Education
- BS (Chemical Engineering) University of Illinois at Urbana-Champaign, 2003
- MS (Mechanical Engineering) University of Illinois at Urbana-Champaign, 2005
- PhD (Bioengineering) University of Illinois at Urbana-Champaign, 2007
- N.S.F. Postdoctoral Fellow Delft University of Technology, NL, 2008-2010
Honors & Awards
- 2017 Outstanding Translational Research Award
Research Overview
Detection of biomolecules at the nanoscale in micro and nanofluidic channels; biophysics; micro and systems biology; environmental sensing; analytical instrumentation
Selected Research Projects
- Point-of-Care Test for Identifying Gram Negative Urinary Tract Infections in Companion Animals
- – Principal Investigator, National Science Foundation
Department Research Areas
Selected Publications
- Buch, Pranali J., Chai, Yunrong, Goluch, Edgar D. (2021). Bacterial chatter in chronic wound infections. Wound Repair and Regeneration, 29(1),106-116. 10.1111/WRR.12867
- M.K. Kimani, J. Mwagi, E.D. Goluch, Bacterial Sample Concentration and Culture Monitoring using a PEG-Based Osmotic System with Inline Impedance and Voltammetry Measurements, Journal of Analysis and Testing, 3(2), 2019, 166-174
- M.K. Kimani, R. Loo, E.D. Goluch, Biosample Concentration Using Microscale Forward Osmosis with Electrochemical Monitoring, Analytical Chemistry, 91, 2019, 7487-7494
- P.J. Buch, Y. Chai, E.D. Goluch, Treating Polymicrobial Infections in Chronic Diabetic Wounds, Clinical Microbiology Reviews, 32(2), 2019, e00091-18
- J. Sun, N. Tandogan, A.Z. Gu, S. Müftü, E.D. Goluch, K.T. Wan, Quantification of Colloidal Filtration of Polystyrene Micro- Particles on Glass Substrate Using a Microfluidic Device, Colloids and Surfaces B: Biointerfaces 165, 2018, 381-387
- C.R. Santiveri, H.J. Sismaet, M. Kimani, E.D. Goluch Electrochemical Detection of Pseudomonas Aeruginosa in Polymicrobial Environments, ChemistrySelect, 3(11), 2018 2926-2930
- H.J. Sismaet, E.D. Goluch, Electrochemical Probes of Microbial Community Behavior, Annual Review of Analytical Chemistry, 2018
- P.N. Abadian, P.J. Buch, E.D. Goluch, J. Li, Z. Zhang Real-Time Monitoring of Urinary Encrustation Using a Quartz Crystal Microbalance, Analytical Chemistry, 90(3), 2018, 1531-1535
Jul 22, 2022
Six Engineering Spinouts Selected as Eddies Finalists
Six spinout companies that were created by engineering faculty have been selected as finalists for the Massachusetts Innovation Network’s innovation competition, The Eddies. Every year, the Massachusetts Innovation Network hosts its signature innovation competition, The Eddies. The Eddies (formerly known as NE Innovation Awards) is the oldest and longest running innovation competition in New England. […]
Apr 21, 2020
Goluch Awarded Patent for Nanofluidic Device
ChE Associate Professor Edgar Goluch was awarded a patent for “Nanofluidic device for isolating, growing, and characterizing microbial cells”.
Jan 09, 2020
Ed Goluch, “Diagnosis in Minutes”
ChE Associate Professor Edgar Goluch was featured in the Angel Invest Boston podcast “Diagnosis in Minutes“.
Jul 10, 2019
Prof. Ed Goluch to give invited Plenary Talk at AIChe Annual Meeting this Fall
ChE Associate Professor Ed Goluch has been invited to give a Plenary Talk at the 2019 American Institute of Chemical Engineers (AIChE) conference in November on “Electrochemical Sensors for Multiplexed Infection Detection and Monitoring”.
Jun 20, 2019
Goluch Awarded Patent for Rapid Bacterial Infection Diagnosis System
ChE Associate Professor Edgar Goluch was awarded a patent for creating a "Diagnostic system and process for rapid bacterial infection diagnosis". Abstract Source: USPTO Methods and devices for monitoring the viability of a biofilm comprising Pseudomonas Aeruginosa bacteria are provided by detecting pyocyanin. The invention relates to electrochemical methods and devices that offer a simple […]
Feb 12, 2019
ChE Student's Paper on Front Page of CMR Website
Chemical Engineering PhD student Pranali Buch, advised by Professor Edgar Goluch, recently had her review paper “Treating Polymicrobial Infections in Chronic Diabetic Wounds” published in Clinical Microbiology Reviews.
Oct 19, 2018
Quickly Diagnosing Infections Leads to Faster Treatments
ChE Associate Professor Edgar Goluch created the company QSM Diagnostics to help diagnose bacterial infections in animals quickly which would allow for faster treatments.
Sep 21, 2018
NU ChE Graduate Student Publication in Collaboration with Wyss Institute/HMS
Research Scientist at the Wyss Institute and current ChE graduate student Daniel Wiegand’s research was featured in the ACS Synthetic Biology article “Establishing a Cell-Free Vibrio natriegens Expression System” for using super fold GFP as a read-out for tweaking a multitude of parameters in order to retain sustained protein expression in the cell-free reaction over a long period of time.
Nov 01, 2017
Researcher and Entrepreneur
ChE Associate Professor Ed Goluch was featured in the Northeastern Magazine’s article “Faster, Cheaper, Better” for taking an idea of an early infection detection system and bringing it to market. His company, QSM Diagnostics, is developing a medical device that will detect bacterial infections in less than five minutes compared to the current three days. […]
Oct 24, 2017
Prof. Goluch gives talk at 3rd Annual Single Cell Analysis USA Congress
ChE Associate Professor Ed Goluch gave a talk at the Third Annual Single Cell Analysis USA Congress in Boston on “Isolating Bacterial Cells and Measuring Metabolites Using Sub-Microfluidic Systems,” which discusses the unique challenges of bacterial cell analysis at the single cell level given their small size and motility.