Bryan James
Assistant Professor,
Chemical Engineering
Office
- 336 Mugar
- 617.373.5735
Lab
- 111 Mugar
Research Focus
Fate, persistence, and toxicity of materials in the environment and the body to inform the design of functional, sustainable, and benign next-generation materials, products, and processes
About
Dr. Bryan D. James is an Assistant Professor in the Department of Chemical Engineering at Northeastern University. He leads the EcoBioMaterials Design Lab focused on creating functional, sustainable, and benign materials for a safer, cleaner future by innovating at each stage of the engineering design process. He actively collaborates globally with academic colleagues, NGOs, and industrial partners, regularly engages with K-12 students and educators, and advises policymakers. Bryan received his B.A.Sc. in materials engineering from the University of Toronto in 2017 and his Ph.D. in materials science and engineering from the University of Florida (UF) in 2021. At UF, as an NIH F31 Predoctoral Fellow under the mentorship of Josephine Allen, Bryan pioneered the use of nucleic acid-collagen complexes for hard and soft tissue engineering and championed investigating sex as a biological variable in biomaterials research, identifying mechanobiological sex differences in vascular cells. Thereafter, Bryan was a Postdoctoral Scholar/Investigator at the Woods Hole Oceanographic Institution (WHOI), working with Mark Hahn, Collin Ward, and Chris Reddy. His postdoctoral research focused on understanding the fate, persistence, and toxicity of plastic in the ocean to inform the rational design of next-generation materials that are safe for people and the planet.
Education
- BASc (Materials Engineering), University of Toronto, 2017
- PhD (Materials Science and Engineering), University of Florida, 2021
Professional Affiliations
- American Chemical Society (ACS)
- American Association for the Advancement of Science (AAAS)
Research Overview
Fate, persistence, and toxicity of materials in the environment and the body to inform the design of functional, sustainable, and benign next-generation materials, products, and processes
Selected Research Projects
- The rationale design of nucleic acids for use as multifunctional, green additives in next-generation plastics
- – Principal Investigator, American Chemical Society
Department Research Areas
Selected Publications
- Pipis, N.*, James, B. D.*, Allen, J. B. Multifunctional DNA-Collagen Biomaterials: Developmental Advances and Biomedical Applications. ACS Biomaterials Science & Engineering. (2025).
- James, B. D., Medvedev, A. V., Medvedeva, L. A., Martsen, E., Gorman, K. L., Lin, B., Makarov, S. S., Aluwihare, L. I., de Vos, A., Reddy, C. M., Hahn, M. E. Burnt plastic (pyroplastic) from the M/V X-Press Pearl ship fire and plastic spill contain compounds that activate endocrine and metabolism-related human and fish transcription factors. Environment & Health. (2024).
- James, B. D., Sun, Y., Pate, K., Shankar, R., Izallalen, M., Mazumder, S., Perri, S. T., Houston, K. R., Edwards, B., de Wit, J., Reddy, C. M., Ward, C. P. Foaming enables material-efficient bioplastic products with minimal persistence. ACS Sustainable Chemistry & Engineering. (2024).
- James, B. D., Medvedev, A. V., Makarov, S. S., Nelson, R. K., Reddy, C. M., Hahn, M. E. Moldable plastics (polycaprolactone) can be acutely toxic to developing zebrafish and activate nuclear receptors in mammalian cells. ACS Biomaterials Science & Engineering. 10, 8, 5237–5251 (2024).
- James, B. D., Sun, Y., Izallalen, M., Mazumder, S., Perri, S. T., Edwards, B., de Wit, J., Reddy, C. M., Ward, C. P. Strategies to reduce the environmental lifetimes of drinking straws in the coastal ocean. ACS Sustainable Chemistry & Engineering. 12, 6, 2404-24011 (2024).
- James, B. D., Ward, C. P., Hahn, M. E., Thorpe, S. J., Reddy, C. M. Minimizing the environmental impacts of plastic pollution through ecodesign of products with low environmental persistence. ACS Sustainable Chemistry & Engineering 12, 3, 1185-1194 (2024).

Dec 11, 2024
New Faculty Spotlight: Bryan James
Bryan James joins the chemical engineering department in January 2025 as an assistant professor.