Jessica Oakes

Associate Professor,  Bioengineering

Contact

Office

  • 229 ISEC
  • 617.373.7080

Research Focus

Myself and my research team are passionate about uncovering cell and molecular mediated changes in respiratory function following exposure to environmental pollutants through state-of-the-art computational and experimental models. We are also interested in direct therapeutic delivery to the lungs.

Education

  • 2013 University of California, San Diego, PhD in Mechanical and Aerospace Engineering
  • 2008 Rochester Institute of Technology, MS in Mechanical Engineering

Research Overview

Myself and my research team are passionate about uncovering cell and molecular mediated changes in respiratory function following exposure to environmental pollutants through state-of-the-art computational and experimental models. We are also interested in direct therapeutic delivery to the lungs.

Respiratory Innovation and Simulation Team (RESIST)

We combine state-of-the-art experimental and numerical methods to quantify the health impacts of inhaled toxins (e.g. e-cigs) or to optimize inhaled therapeutics.

Respiratory Innovation and Simulation Team (RESIST)

Selected Research Projects

Research Centers and Institutes

Selected Publications

  • Héctor Millán Cotto+, Yasmeen M. Farra, Alex Sorenson+, Chiara Bellini, Jessica M. Oakes*. Longitudinal Electronic Cigarette Exposures Impair Respiratory Structure and Function in the Female Apoe-/- Mouse Model. Nicotine and Tobacco Research. https://doi.org/10.1093/ntr/ntaf084
  • Jessica M. Oakes*. The Utility of Hybrid In Silico Models of Airflow and Aerosol Dosimetry in the Lung. Journal of Biomechanics. 2024, 128: 112126.
  • Victoria A. Williams, Luke R. Perreault, Nicholas A. Micovic, Charbel T. Yazbeck, Jessica M. Oakes*, Chiara Bellini. Impact of Wildfires on Cardiovascular Health. Circulation Research. 2024, 134: 1061-1082.
  • Jacqueline Matz+, Mireia Perera Gonzalez+, Peter Niedbalski, Hannah Kim+, Michael Gollner, Chiara Bellini, Jessica M. Oakes*. Assessment of Left Lung Remodeling with Magnetic Resonance Imaging in a Murine Model Following Exposure to Douglas Fir Smoke. Journal of Biomechanical Engineering. 2024: 146: 071010.
  • Meagan Morgan, Jacqueline Matz+, Yasmeen Farra, Alexandra Vergara-Anglim, Chiara Bellini, Jessica M. Oakes*, Sandra J. Shefelbine. E-cigarette and wildfire smoke exposure effect on bone biomechanical properties in murine models. Journal of Biomechanics. 23:162:111879. 10.1016/j.jbiomech.2023.111879
  • Jessica M. Oakes*, Israel Amirav, Josué Sznitman. Pediatric inhalation therapy and the aerodynamic rationale for age-based aerosol sizes. Expert Opinion in Drug Delivery. 20: 1037-1040. https://doi.org/10.1080/17425247.2023.2209314

Faculty

May 27, 2025

Oakes Receives ISAM 2025 Young Investigator Award

BioE Associate Professor Jessica Oakes received the International Society for Aerosols in Medicine (ISAM) 2025 Young Investigator Award. This award recognizes a scientist under 40 who has made significant contributions to the field of aerosols in medicine.

firefighter with hose during burning house

Faculty

Jan 24, 2025

Researchers Warn of Damaging Effects of Smoke From California Fires

Bioengineering Associate Professors Chiara Bellini and Jessica Oakes highlight the dangerous health effects of inhaling wildfire smoke. Their research provides insight into the risks the California wildfires pose for people’s respiratory and cardiovascular systems.

Students

Oct 28, 2024

Best Poster Presentation Award at Fourth Aerosol Dosimetry Meeting

Charbel Yazbeck, PhD’28, bioengineering, advised by BioE Associate Professor Jessica Oakes, was awarded the best student poster presentation at the Fourth Aerosol Dosimetry Meeting, for his poster titled “Modeling and Evaluating the Pulmonary Impacts of a Wildland Firefighting Career Through Equivalent Murine Exposure.”

Faculty

Jun 03, 2024

Oakes Recognized by ASME in Top 25 Early Career Professionals

American Society of Mechanical Engineers recognized BioE Associate Professor Jessica Oakes on the Watch List of top 25 early career professionals. Her ASME magazine profile highlighted her work “What Happens When We Inhale Things?” with applications from wildfire smoke to e-cigarettes.

Faculty

Aug 07, 2023

Young Scholars Program for Local High School Students Finishes Strong

High school seniors engage in diverse engineering research during Northeastern’s Young Scholars Program, mentored by COE faculty and students.

Faculty

Jul 05, 2023

$3.8M NIH Award on the Cardiovascular and Respiratory Effects of E-cigarettes and Cigarettes

BioE Associate Professors Chiara Bellini and Jessica Oakes received a $3.8 million NIH grant for “Cardiopulmonary Outcomes of Dual Cigarette and E-cigarette Use in Animal Models of Chronic Exposure.”

Faculty

Jan 25, 2023

Spring 2023 PEAK Experiences Awardees for Undergrad Research

Several engineering and science students mentored by COE faculty are recipients of Spring 2023 PEAK Experiences Awards from Northeastern’s Office of Undergraduate Research and Fellowships.

Faculty

Dec 20, 2022

Oakes Receives ASME 2023 Y.C. Fung Early Career Award

BioE Assistant Professor Jessica Oakes was selected as the 2023 Y.C. Fung Early Career Award Medalist for outstanding work in respiratory mechanics that has significantly advanced the understanding of asthma, smoking, and inhalable drug delivery, and for strong advocacy in diversity, equity, and inclusion efforts.

Jessica Oakes and Chiara Bellini

Faculty

Feb 23, 2022

$3.4M NIH ONES Award to Study the Impact of Wildfire Smoke on Human Health

BioE Assistant Professors Jessica Oakes and Chiara Bellini were awarded a 5-year, $3.4M NIH grant for “Cardiopulmonary Risk Assessment from Smoke Exposure at the Wildland Urban Interface.”

Faculty

Jan 30, 2020

Translating the ‘Mastermind’ Concept from Business to Academia

Assistant Professors Danielle Levac (Bouvé), Emily Zimmerman (Bouvé), Kristen Allison (Bouvé), Abigail Koppes (ChE), Sarah Ostadabbas (ECE), Jessica Oakes (BioE), and Associate Professor Eno Ebong (ChE) were awarded a 2020 ADVANCE Mutual Mentoring Advancement Program (M2AP) Grant for “Translating the ‘Mastermind’ Concept from Business to Academia: Facilitating Peer mentorship among female PIs leading active research labs”.

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