Sara Rouhanifard

Assistant Professor,  Bioengineering

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Office

  • 617.373.2226

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Research Focus

Developing chemical approaches to track and quantify important RNA processing events and modifications in single cells; DNA: protein interactions that drive differences in gene expression; understanding differences in RNA expression and the impacts on disease and development.

About

Joins the bioengineering department in January 2019.

Education

  • PhD, Biochemistry, Albert Einstein College of Medicine, 2014
  • MS, Biochemistry, Albert Einstein College of Medicine, 2012
  • BS, Biochemistry and Molecular Biology, University of Massachusetts, Amherst 2007

Honors & Awards

  • Ruth S. Kirschstein F32 National Research Service Award

Research Overview

Developing chemical approaches to track and quantify important RNA processing events and modifications in single cells; DNA: protein interactions that drive differences in gene expression; understanding differences in RNA expression and the impacts on disease and development.

Rouhanifard Lab

Our lab uses chemical, biological and computational approaches to address both fundamental and applied questions in biology and medicine. We aim to foster an interdisciplinary and translational research environment in which biologists, chemists, and engineers can work together to solve exciting problems.

Rouhanifard Lab

Selected Publications

  • S.H. Rouhanifard, I.A. Mellis, M. Dunagin, S. Bayatpour, C.L. Jiang, I. Dardani, O. Symmons, B. Emert, E. Torre, A. Cote, A. Sullivan, J.A. Stamatoyannopoulos, A. Raj ClampFISH Detects Individual Nucleic Acid Molecules Using Click Chemistry–Based Amplification, Nature Biotechnology, 37(1), 2019, 84-89
  • S.H. Rouhanifard, A.L. Aguilar, L. Meng, K.W. Moremen, P. Wu, Engineered Glycocalyx Regulates Stem Cell Proliferation in Murine Crypt Organoids, Cell Chemical Biology, 25(4), 2018, 439-446
  • C.N. Casson, J.L. Doerner, A.M. Copenhaver, J. Ramirez, A.M. Holmgren, M.A. Boyer, I.J. Siddarthan, S.H. Rouhanifard, A. Raj, S. Shin, Neutrophils and Ly6Chi Monocytes Collaborate in Generating an Optimal Cytokine Response that Protects Against Pulmonary Legionella Pneumophila Infection, PLOS Pathogens, 13(4), 2017
  • I.A. Mellis, R. Gupte, A. Raj, S.H. Rouhanifard Visualizing Adenosine to Inosine RNA Editing in Single Mammalian Cells, Nature Methods, 8, 2017, 801-804
  • S.H. Rouhanifard, A. Lopez-Aguilar, P. Wu, CHoMP: A Chemoenzymatic Histology Method Using ‘Clickable’ Probes, ChemBioChem, 15(18), 2014, 2667-2673
Jeffrey Ruberti

Faculty

May 21, 2020

Ruberti Awarded Grant for Low-Cost COVID-19 Diagnostics Testing

BioE Professor Jeffrey Ruberti, in collaboration with the University of California-Los Angeles and University of Massachusetts Amherst, was awarded a $150K NSF RAPID grant for “Low-Cost, Non-invasive, Fast Sample Collection System for COVID-19 Viral Load Level Diagnosis: Point-of-Care and Environmental Testing.”

Faculty

Apr 11, 2020

FY21 TIER 1 Award Recipients

Congratulations to the 19 COE faculty and affiliates who were recipients of FY21 TIER 1 Interdisciplinary Research Seed Grants for 13 different projects.

Faculty

Apr 09, 2019

FY20 TIER 1 Award Recipients

25 COE faculty and affiliates were recipients of FY20 TIER 1 Interdisciplinary Research Seed Grants for 18 different projects representing up to $900K dollars of investment in research.

Faculty

Jan 04, 2019

New Faculty Spotlight: Sara Rouhanifard

Sara Rouhanifard joins the Bioengineering department in January 2019 as an Assistant Professor.

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