Amir Vahabikashi Download

Amir Vahabikashi

Assistant Professor,  Bioengineering

Contact

Social Media

Office

  • ISEC 319

Related Links

Research Focus

Cell and nucleus mechanobiology, soft bioelectronics for organoid/tissue scale mechanobiology and regenerative engineering, mechanotransduction, implantable bioelectronics

Education

  • PhD, Biomedical Engineering, Northwestern University, 2016

Professional Affiliations

  • International Society for Eye Research (ISER)
  • Association for Research in Vision and Ophthalmology (ARVO)
  • Biomedical Engineering Society (BMES)
  • American Society for Cell Biology (ASCB)

Research Overview

Cell and nucleus mechanobiology, soft bioelectronics for organoid/tissue scale mechanobiology and regenerative engineering, mechanotransduction, implantable bioelectronics

Vahabikashi Lab

Our lab operates at the intersection of multiscale mechanobiology and soft bioelectronics. We bring together expertise from engineering, biology, materials science, and medicine to tackle complex problems in human health. Our research pursues three interconnected goals:

  1. We uncover the mechanobiological mechanisms that underlie disease.

  2. We develop advanced bioelectronic interfaces integrated with three-dimensional multicellular biological systems for disease modeling.

  3. We translate our insights into innovative therapeutics, medical devices, and regenerative technologies that address unmet clinical needs.

Vahabikashi Lab

Research Centers and Institutes

Department Research Areas

Selected Publications

  • Sivagurunathan S., Vahabikashi A., Yang H., Zhang J., Vazquez K., Rajasundaram D., Politanska Y., Abdala-Valencia H., Notbohm J., Guo M., Adam SA., and Goldman RD. Expression of vimentin alters cell mechanics, cell-cell adhesion, and gene expression profiles suggesting the induction of a hybrid EMT in human mammary epithelial cells. Front. Cell Dev. Biol, 10:929495, 2022.
  • Vahabikashi, A., Sivagurunathan, S., Nicdao, FAS., Han, YL., Park, CY., Kittisopikul, M., Wong, X., Tran, JR., Gundersen, GG., Reddy, KL., Luxton, GWG., Guo, M., Fredberg, JJ., Zheng, Y., Adam, SA., Goldman, RD. Nuclear lamin isoforms differentially contribute to LINC complex-dependent nucleocytoskeletal coupling and whole-cell mechanics. Proceedings of the National Academy of Sciences of USA, 119: e2121816119, 2022.
  • Vahabikashi, A., Adam, SA., Medalia, O., Goldman, RD. Nuclear lamins: Structure and function in
    mechanobiology. APL Bioengineering, 6: 011503, 2022.
  • McDowell, C. M., K. Kizhatil, M. H. Elliott, D. R. Overby, J. van Batenburg-Sherwood, J. C. Millar, M. H. Kuehn, G. Zode, T. S. Acott, M. G. Anderson, S. K. Bhattacharya, J. A. Bertrand, T. Borras, D. E. Bovenkamp, L. Cheng, J. Danias, M. L. De Ieso, Y. Du, J. A. Faralli, R. Fuchshofer, P. S. Ganapathy, H. Gong, S. Herberg, H. Hernandez, P. Humphries, S. W. M. John, P. L. Kaufman, K. E. Keller, M. J. Kelley, R. A. Kelly, D. Krizaj, A. Kumar, B. C. Leonard, R. L. Lieberman, P. Liton, Y. Liu, K. C. Liu, N. N. Lopez, W. Mao, T. Mavlyutov, F. McDonnell, G. J. McLellan, P. Mzyk, A. Nartey, L. R. Pasquale, G. C. Patel, P. P. Pattabiraman, D. M. Peters, V. Raghunathan, P. V. Rao, N. Rayana, U. Raychaudhuri, E. Reina-Torres, R. Ren, D. Rhee, U. R. Chowdhury, J. R. Samples, E. G. Samples, N. Sharif, J. S. Schuman, V. C. Sheffield, C. H. Stevenson, A. Soundararajan, P. Subramanian, C. K. Sugali, Y. Sun, C. B. Toris, K. Y. Torrejon, Vahabikashi, A., J. A. Vranka, T. Wang, C. E. Willoughby, C. Xin, H. Yun, H. F. Zhang, M. P. Fautsch, E. R. Tamm, A. F. Clark, C. R. Ethier and W. D. Stamer. Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms. Investigative Ophthalmology & Visual Science 63(2): 12-12, 2022.
  • Vincent, M., Stack, T., Vahabikashi, A., Li, G., Perkumas, K., Ren, R., Gong, H., Stamer, D., Johnson, M. Scott, E. Surface Engineering of FLT4-Targeted Nanocarriers Enhances Cell-Softening Glaucoma Therapy. ACS Applied Materials & Interfaces 13: 32823-32836, 2021.

 

Link to Goggle Scholar

Students: Undergraduate

Oct 03, 2025

Fall 2025 PEAK Experiences Awardees for Undergrad Research

Several COE, COS, and Khoury students mentored by COE faculty are recipients of the Fall 2025 PEAK Experiences Awards from Northeastern’s Office of Undergraduate Research and Fellowships.

Amir Vahabikashi

Faculty

Jul 06, 2023

New Faculty Spotlight: Amir Vahabikashi

Amir Vahabikashi joins the Bioengineering department in July 2023 as an Assistant Professor.

View All Related News