Wei Xie
Assistant Professor, Mechanical and Industrial Engineering
Contact
- w.xie@northeastern.edu
- 334 SN
360 Huntington Avenue
Boston, MA 02115
Office
- 453 SN
- 617.373.6917
Related Links
Research Focus
Interpretable AI, IoT, computer simulation, data integrity and big data analytics, data-driven stochastic optimization, blockchain design and development for complex end-to-end cyber-physical system learning and risk management with applications, including biopharmaceutical manufacturing and supply chains, smart power grids with renewable energy, and health care
Education
- PhD, Northwestern University, Industrial Engineering and Management Sciences, 2014
Honors & Awards
- 2023 Constantinos Mavroidis Translational Research Faculty Award
- Outstanding Publication Award from the INFORMS Simulation Society
Professional Affiliations
- Technical Activity Committee (TAC) for The National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL)
- Institute for Operations Research and The Management Sciences (INFORMS)
- Transportation Research Board
Research Overview
Interpretable AI, IoT, computer simulation, data integrity and big data analytics, data-driven stochastic optimization, blockchain design and development for complex end-to-end cyber-physical system learning and risk management with applications, including biopharmaceutical manufacturing and supply chains, smart power grids with renewable energy, and health care
Selected Research Projects
- Advanced FISH Assay and Mechanism Hybrid Surrogate to Improve mRNA Vaccine Potency Assessment and Prediction
- – Principal Investigator, National Institute for Innovation in Manufacturing Biopharmaceuticals
- Advanced Bioprocessing Sensor and Analytical Technologies for Induced Pluripotent Stem Cell Culture Online Monitoring and Automation
- – Principal Investigator, National Institute for Innovation in Manufacturing Biopharmaceuticals
Department Research Areas
Selected Publications
- H. Zheng, W. Xie, B. Feng, Green Simulation Assisted Reinforcement Learning with Model Risk for Biomanufacturing Learning and Control, Winter Simulation Conference, 2020
- K. Wang, W. Xie, W. Wu, B. Wang, J. Pei, M. Baker, Q. Zhou Simulation-Based Digital Twin Development for Blockchain Enabled End-to-End Industrial Hemp Supply Chain Risk Management, Winter Simulation Conference, 2020
- W. Xie, P. Zhang, R. Chen, Z. Zhou, A Nonparametric Bayesian Framework for Short-Term Wind Power Probabilistic Forecast, IEEE Transactions on Power Systems, 34(1), 2019
- B. Wang, Q. Zhang, W. Xie, Bayesian Sequential Data Collection for Stochastic Simulation Calibration Using Detailed Sample Paths, European Journal of Operational Research, 227(1), 2019, 300-316
- W. Xie, P. Zhang, R. Chen, Z. Zhou, A Nonparametric Bayesian Framework for Short-Term Wind Power Probabilistic Forecast, IEEE Transactions on Power Systems, 2018, 1-1
- W. Xie, P. Zhang, I. Ryzhov, A Simulation-Based Prediction Framework for Stochastic System Dynamic Risk Management, Winter Simulation Conference, 2018
- W. Xie, B. Wang, Q. Zhang, Metamodel-Assisted Risk Analysis for Stochastic Simulation with Input Uncertainty, Winter Simulation Conference, 2018
- W. Xie, C. Li, P. Zhang, A Factor-Based Bayesian Framework for Risk Analysis in Large-Scale Stochastic Simulations, ACM Transactions on Modeling and Computer Simulation, 27(4), 2017, 1-31

Apr 06, 2023
Avoiding Errors by Thoroughly Understanding Bioprocess Mechanisms
MIE Assistant Professor Wei Xie’s research study on biomanufacturing process hybrid modeling, digital twin, and machine learning was featured in the Genetic Engineering & Biotechnology News article “Avoiding Errors by Thoroughly Understanding Bioprocess Mechanisms.”

Apr 06, 2023
Modeling Uncertainty in Process Development
MIE Assistant Professor Wei Xie’s research on uncertainty analysis was featured in the Genetic Engineering & Biotechnology News article “Modeling Uncertainty in Process Development.”

Mar 09, 2023
Xie Awarded NIIMBL Grant for mRNA Vaccine Potency Assessment and Prediction
Wei Xie, assistant professor of mechanical and industrial engineering, has received an award from the National Institute for Innovation in Manufacturing Biopharmaceuticals for “Advanced FISH Assay and Mechanism Hybrid Surrogate to Improve mRNA Vaccine Potency Assessment and Prediction.”
Jan 24, 2023
Faculty and Staff Awards 2023
Congratulations to all the winners of the faculty and staff awards, and to everyone for their hard work and dedication during the 2022-2023 academic school year. COE Distinguished Faculty Award Yun Raymond Fu, ECE Auroop Ganguly, CEE Luke Landherr, ChE Sinan Müftü, MIE Mark Niedre, BioE Alison Nogueira, Co-op Nian Sun, ECE Constantinos Mavroidis Translational […]

Aug 29, 2022
Xie Awarded $2 Million NIIMBL Stem Cell Research Grant
MIE Assistant Professor Wei Xie received a $2M award from the National Institute for Innovation in Manufacturing Biopharmaceuticals, for the project “Advanced Bioprocessing Sensor and Analytical Technologies for Induced Pluripotent Stem Cell Culture Online Monitoring and Automation.”

May 11, 2021
Just What the Doctor Ordered
Human beings are some of the most complex systems in the world, and responses to illness, disease, and impairments manifest in countless different ways. When it comes to making sure that your system stays up and running, healthcare professionals typically have their own deep well of knowledge—but the addition of artificial intelligence tools offers unprecedented […]

Aug 30, 2018
New Faculty Spotlight: Wei Xie
Wei Xie joins the Mechanical & Industrial Engineering department in August 2018 as an Assistant Professor.