Carrier Awarded $230K Grant
The Advanced Drug Delivery Research (ADDRES) Laboratory at Northeastern University is headed by Dr. Rebecca Carrier of Northeastern’s Department of Chemical Engineering.
The ADDRES Lab studies transport phenomena in biological systems, with a current focus on the intestinal environment, via development of theoretical and tissue-engineered cell culture models. Computational models (molecular and macroscopic) predict what drug delivery systems will enhance absorption of a compound with specific physical and chemical properties. Macroscopic systems-based models of the intestinal drug delivery environment are in the form of mass balances and kinetic equations describing drug release, dissolution, precipitation, and absorption. Mechanistic studies are conducted to enhance fundamental understanding of these processes. Our tissue engineering focus is on developing a biomimetic scaffold with crypt-villus structure for intestinal epithelial cell culture.
View the project information here.