Mansoor Amiji
University Distinguished Professor, Pharmaceutical Sciences
University Distinguished Professor, Chemical Engineering
Affiliated Faculty, Bioengineering
Contact
- m.amiji@northeastern.edu
- 360 Huntington Avenue
Boston, MA 02115
Office
- 140 The Fenway, Room 165
- 617.373.3137
Related Links
Research Focus
Polymeric biomaterials, drug delivery systems, nanomedical technologies
Education
- BS, Pharmacy (magna cum laude), Northeastern University
- PhD, Pharmaceutics, Purdue University
Honors & Awards
- T. Nagai Award, Controlled Release Society
- Fellow, America Association of Pharmaceutical Scientists (AAPS)
- Fellow, American Institute for Medical and Biological Engineers (AIMBE)
- Fellow, Controlled Release Society
- Charivate Analytics Highly Cited Author (top 1%)
- Distinguished Alumni Award, Purdue University College of Pharmacy
Professional Affiliations
- American Association of Pharmaceutical Scientists, Fellow
- Controlled Release Society, Fellow
Research Overview
Polymeric biomaterials, drug delivery systems, nanomedical technologies
Selected Research Projects
- Combination Strategy for the Treatment of Advanced Pancreatic Cancer
- – Principal Investigator, National Institutes of Health
- Development and Validation of a Novel Cas13a and Nanoparticle Guide-RNA Delivery System that Allows Precise Ablation of Host Macrophage Populations in a Humanized Mouse Model
- – Principal Investigator, Jackson Laboratories on a National Institutes of Health
- Direct CNS Delivery System for BDNF AntagoNATs using Heterotopic Mucosal Grafting for the Treatment of Parkinson’s Disease
- – Principal Investigator, National Institutes of Health
Department Research Areas
Selected Publications
- J. Bae, N. Parayath, W. Ma, M. Amiji, N. Munshi, K. Anderson, Bcma Peptide Engineered Nanoparticles Enhance Induction and Function of Antigen Specific Cd8+ Cytotoxic T Lymphocytes Against Multiple Myeloma, Nature – Leukemia, 34, 2020, 210–223
- N.N. Parayath, S. Padmakumar, M. Amiji, Extracellular Vesicle-Mediated Nucleic Acid Transfer and Reprogramming in the Tumor Microenvironment, Cancer Letters, 482(10), 2020, 33-43
- G. Ahmad, G. Mackenzie, J. Egan, M. Amiji, Dha-Sbt-1214 Taxoid Nanoemulsion and Anti-Pd-L1 Antibody Combination Therapy Enhances Antitumor Efficacy in a Syngeneic Pancreatic Adenocarcinoma Model, Molecular Cancer Therapeutics, 18(11), 2019, 961-1972
- D. Chen, N. Parayath, S. Ganesh, W. Wang, M. Amiji, Role of Apolipoprotein-and Vitronectin-Enriched Protein Corona on Lipid Nanoparticles for in Vivo Targeted Delivery and Transfection of Oligonucleotides in Murine Tumor Models, Nanoscale, 11, 2019, 18806–18824
Jun 25, 2024
Will the New COVID FLiRT Variant Lead to a Summer Surge? Watch for These Symptoms, Experts Say
Bouvé/ChE University Distinguished Professor Mansoor Amiji was featured in the Medical Xpress article “Will the New COVID FLiRT Variant Lead to a Summer Surge? Watch for These Symptoms, Experts Say.”
Jun 13, 2024
Combo COVID-19-Flu Shot Could Have Broad Appeal
Bouvé/ChE University Distinguished Professor Mansoor Amiji says the convenience of a combined mRNA COVID-19 and flu shot, which successfully completed a late-stage trial at Moderna, could drive up the percentage of people vaccinated against the coronavirus.
Jun 10, 2024
New Approaches for Blood Disease Treatments
Bouvé/ChE University Distinguished Professor Mansoor Amiji’s research on “Lipid Nanoparticles Target Haematopoietic Stem Cells” was published in Nature Nanotechnology.
May 02, 2024
AstraZeneca Admits Vaccine Can Cause Rare Blood-Clotting Condition
Bouvé/ChE University Distinguished Professor Mansoor Amiji gives insight into the risk of getting thrombosis with thrombocytopenia syndrome, or TTS, from the AstraZeneca vaccine for COVID-19.
Mar 25, 2024
Three Faculty Selected as AIMBE Fellows
Bouvé/ChE University Distinguished Professor Mansoor Amiji, ChE/BioE Associate Professor Eno Ebong, and ECE/Khoury Professor Yun Raymond Fu were selected as Class of 2024 Fellows for the American Institute for Medical and Biological Engineering.
Feb 27, 2024
Avoiding Safety Risks for mRNA Therapeutics
Bouvé/ChE University Distinguished Professor Mansoor Amiji co-authored a paper in Nature Reviews Drug Discovery outlining several strategies to check for toxicity at the preclinical level of mRNA therapeutics to ensure patient safety.
Jan 17, 2024
New Cancer Vaccines Could Provide Beneficial Alternative Therapy
Bouvé/ChE University Distinguished Professor Mansoor Amiji sees the promise of new cancer vaccines amid encouraging results from treatment studies.
Dec 07, 2023
2023 Stanford University Annual Assessment of Author Citations
The following COE professors are among the top scientists worldwide selected by Stanford University representing the top 2% of the most-cited scientists with single-year impact in various disciplines. The selection is based on the top 100,000 by c-score (with and without self-citations) or a percentile rank of 2% or above. The list below includes those […]
Nov 03, 2023
Understanding the Efficacy of the COVID-19 Vaccine
Bouve/ChE University Distinguished Professor Mansoor Amiji explains how the COVID-19 vaccine is designed to prevent severe illness, hospitalization, and death, rather than to eliminate infection entirely.
Mar 02, 2023
New Treatments for Pancreatic Cancer
Bouve/ChE University Distinguished Professor Mansoor Amiji is working with UC Davis and drug developer TargaGenix to create new treatments for pancreatic cancer.