Penny Beuning

Selected Publications

• Strezsak, Steven R., Beuning, Penny J., Skizim, Nicholas J. (2021) Complete Enzymatic Digestion of Double-Stranded RNA to Nucleosides Enables Accurate Quantification of dsRNA. Analytical Methods 13, 179-185. 10.1039/D0AY01498B
• Naufer, M. Nabuan, Morse, Michael, Björg Möller, Guðfríður, McIsaac, James, Rouzina, Ioulia, Beuning, Penny J., Williams, Mark C. (2021) Multiprotein E. coli SSB-ssDNA complex show both stable binding and rapid dissociation due to interprotein interactions. Nucleic Acids Research 49, 1532-1549. 10.1039/nar/gkaa1267
• L. Ngu, J.N. Winters, K. Nguyen, K.E. Ramos, N.A. DeLateur, L. Makowski, P.C. Whitford, M.J. Ondrechen, P.J. Beuning Probing Remote Residues Important for Catalysis in Escherichia Coli Ornithine Transcarbamoylase, PLoS One 15(2), 2020, e0228487
• K.R. Moulton, A. Sadiki, B.N. Koleva, L.J. Ombelets, T.H. Tran, S. Liu, B. Wang, H. Chen, E. Micheloni, P.J. Beuning, G.A. O’Doherty, Z.S. Zhou, Site-Specific Reversible Protein Modification: Transglutaminase-Catalyzed Glutamine Conjugation and Bioorthogonal Light-Mediated Removal, Bioconjugate Chemistry, 30, 2019, 1617-1621
• N.M. Antczak, A.R. Walker, H.R. Stern, E.M. Leddin, T.A. Coulther, C. Palad, R.J. Swett, G.A. Cisneros, P.J. Beuning, Characterization of Nine Cancer-Associated Variants in Human DNA Polymerase K, Chemical Research in Toxicology, 31, 2018, 697-711
• C.L. Mills, R. Garg, J.S. Lee, L. Tian, A. Suciu, G. Cooperman, P.J. Beuning, M.J. Ondrechen, Functional Classification of Protein Structures by Local Structure Matching in Graph Representation, Protein Science, 27, 2018, 1125-1135
• R. Parasuram, T.A. Coulther, J.M. Hollander, E. Keston Smith, M.J. Ondrechen, P.J. Beuning, Prediction of Active Site and Distal Residues in E. coli DNA Polymerase III Alpha Polymerase Activity, Biochemistry, 57(7), 2018, 1063–1072

Faculty

Aug 06, 2024

Studying Proteins Involved in the Urea Cycle

BioE/COS Professor Lee Makowski, BioE Affiliate Faculty Penny Beuning, and Mary Jo Ondrechen had their research on “Revisiting the Roles of Catalytic Residues in Human Ornithine Transcarbamylase” published in Biochemistry.

Faculty

Jun 27, 2019

Predicting Protein Functions from 3D Structures

ECE Professor Deniz Erdogmus (co-PI) and affiliated BioE Professors Mary Jo Ondrechen (PI) and Penny Beuning (co-PI) were awarded a $600K NSF grant for “Mining for mechanistic information to predict protein function”.

Faculty

Aug 21, 2018

$1M NSF Grant to Advance the Study of Single-Molecule Research

BioE Professor Jeffrey Ruberti (co-PI) along with bioengineering affiliated and College of Science faculty, including Professor Mark Williams (PI), and Associate Professors Penny Beuning (co-PI), Meni Wanunu (co-PI), and Ke Zhang (co-PI) were awarded a $1M NSF grant for the “Acquisition of a Lumick’s SuperC-TRAP correlative optical tweezers and fluorescence microscope (CTFM) system.”

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