Ryan Koppes

Associate Professor,  Chemical Engineering
Affiliated Faculty,  Bioengineering

Contact

Social Media

Office

  • 339 Mugar
  • 617.373.8547

Lab

  • 111 Mugar
  • 617.373.8161

Research Focus

Neural interface technology, tissue engineering, and musculoskeletal biomechanics

About

Joined the Chemical Engineering Department in Fall 2015.

Education

  • PhD (2013) Rensselaer Polytechnic Institute, Biomedical Engineering
  • MS (2010) Rensselaer Polytechnic Institute, Biomedical Engineering, area of concentration: Muscle Tissue Engineering
  • BS (2008) Rensselaer Polytechnic Institute, Biomedical Engineering, area of concentration: Biomaterials

Honors & Awards

  • NIH National Institute of Biomedical Imaging and Bioengineering Trailblazer Award for New and Early Stage Investigators
  • Gilda Barbino Excellence in Mentoring Award

Professional Affiliations

  • American Society for Mechanical Engineers
  • Biophysical Society
  • Biomedical Engineering Society
  • Materials Research Society

Research Overview

Neural interface technology, tissue engineering, and musculoskeletal biomechanics

Laboratory for Neuromodulation and Neuromuscular Repair

We study the physical bridge between cells and electronics to improve nerve gap and prosthetic technologies. We’re also interested in neuron interactions with the heart to help relieve the healthcare burden of heart failure. Located in Boston, our group is able to join with other top universities to collaborate on ground breaking research.

Selected Research Projects

Selected Publications

  • Bindas, Adam J., Kulkarni, Subhash, Koppes, Ryan A., Koppes, Abigail N. (2021). Parkinson’s Disease and the Gut: Models of an Emerging Relationship. Acta Biomaterialia, 10.1016/J.ACTBIO.2021.03.071
  • Diaz Vera, David, Soucy, Jonathan R., Lee, Audrey, Koppes, Ryan A., Koppes, Abigail N. (2021). Light irradiation of peripheral nerve cells: Wavelength impacts primary sensory neuron outgrowth in vitro. Journal of Photochemistry and Photobiology B: Biology, 215,112105. 10.1016/J.JPHOTOBIOL.2020.112105
  • Ventre, Daniel M., Cluff, Avery, Gagnon, Christian, Diaz Vera, David, Koppes, Ryan A., Koppes, Abigail N. (2021). The effects of low intensity focused ultrasonic stimulation on dorsal root ganglion neurons and Schwann cells in vitro. Journal of Neuroscience Research, 99(1),374-391. 10.1002/JNR.24700
  • S. Hosic, W. Lake, E. Stas, R.A. Koppes, D.T. Breault, S.K. Murthy, A.N. Koppes, Cholinergic Activation of Primary Human Derived Intestinal Epithelium does not Ameliorate TNF-? Induced Injury, Cellular and Molecular Bioengineering, 2020
  • T. Torregrosa, S. Webster, C. Aghaizu, J. Soucy, C. Bertucci, L. Plant, A.N. Koppes, R.A. Koppes Cryopreservation and Functional Analysis of Cardiac Autonomic Neurons, Journal of Neuroscience Methods, 341, 2020, 108724
  • J. Snyder, C. Wang, A.Q. Zhang, Y. Li, J. Luchan, S. Hosic, R. Koppes, R.L. Carrier, A. Koppes, Materials and Microenvironments for Engineering the Intestinal Epithelium, Annals of Biomedical Engineering, 48, 2020, 1916–1940
  • S. Hosic, A. Bindas, M. Puzan, W. Lake, J. Soucy, F. Zhou, R.A. Koppes, D. Breault, S. Murthy, A.N. Koppes Rapid Prototyping of Multilayer Micro Physiological Systems, ACS Biomaterials Science & Engineering, 2020
  • K. Nichols, R. Koppes, A. Koppes, Recent Advancements in Micro Physiological Systems for Neural Development and Disease, Current Opinion in Biomedical Engineering, 14, 2020, 42-51
  • A.R. Spencer, E.S. Sani, J.R. Soucy, C.C. Corbet, A. Primebetova, R.A. Koppes, N. Annabi Bioprinting of a Cell-Laden Conductive Hydrogel Composite, ACS Applied Material Interfaces, 11(34), 2019, 30518-30533
  • J.R. Soucy, A.J. Bindas, A.N. Koppes, R.A. Koppes Instrumented Micro Physiological Systems for Real- Time Measurement and Manipulation of Cellular Electrochemical Processes, iScience, 21, 2019, 521-548

Undergraduate

Nov 15, 2024

Northeastern Nominates 6 COE Students for Prestigious Knight-Hennessy Scholarship

Alex Bender, E’20, MS’20, Matthew Coughlin, E’25, Maya De Los Santos, E’25, Jose Meza Llamosas, E’25, Dominic Pizzarella, E’25, and Daniel Sneyers Pont, E’21, MS’21, were six of eight nominated by Northeastern for the Knight-Hennessy Scholarship, which develops a community of future global leaders to address complex challenges through collaboration and innovation.

Faculty

Sep 04, 2024

New Modeling for Intestinal Health

Research conducted by Kyla Kaiser, PhD’24, chemical engineering, Jessica Snyder, PhD’23, bioengineering, ChE Associate Professors Ryan Koppes, and Abigail Koppes on “A Pumpless, High-Throughput Microphysiological System To Mimic Enteric Innervation of Duodenal Epithelium and the Impact on Barrier Function” was published in Advanced Functional Materials.

Undergraduate

May 08, 2024

2024 URF Scholars Recipients

Several engineering students received 2024 URF Scholars Awards from Northeastern’s Office of Undergraduate Research and Fellowships. URF Scholars are students who are graduating this year and who have earned a PEAK Experiences Award, applied for a distinguished fellowship, or participated in graduate school advising.

Undergraduate

Apr 16, 2024

2024 Condit Award

Dominic Pizzarella, E’25, chemical engineering and biochemistry, won the Sears B. Condit Award, which is awarded annually to one student from each of Northeastern’s undergraduate day colleges and is one of the highest honors that a junior or senior at Northeastern University can receive.

Undergraduate

Jan 11, 2024

Spring 2024 PEAK Experiences Awardees for Undergrad Research

A record number of engineering and science students mentored by COE faculty are recipients of the Spring 2024 PEAK Experiences Awards from Northeastern’s Office of Undergraduate Research and Fellowships.

Faculty

Aug 07, 2023

Young Scholars Program for Local High School Students Finishes Strong

High school seniors engage in diverse engineering research during Northeastern’s Young Scholars Program, mentored by COE faculty and students.

Faculty

Apr 27, 2023

Summer 2023 PEAK Experiences Awards for Undergrad Research

Several engineering and science students mentored by COE faculty are recipients of the Summer 2023 PEAK Experiences Awards from Northeastern’s Office of Undergraduate Research and Fellowships.

Faculty

Jan 25, 2023

Spring 2023 PEAK Experiences Awardees for Undergrad Research

Several engineering and science students mentored by COE faculty are recipients of Spring 2023 PEAK Experiences Awards from Northeastern’s Office of Undergraduate Research and Fellowships.

Faculty

Jan 17, 2023

Fall 2022 Spark Fund Awardees

ChE/COS Associate Professor Carolyn Lee-Parsons, ECE Professor Edmund Yeh, ChE Assistant Professor Ryan Koppes, and MIE Associate Professor Yaning Li are recipients of the Fall 2022 Spark Fund Awards from Northeastern’s Center for Research Innovation.

Faculty

Dec 15, 2022

Regenerating Major Nerve Injuries With a Different Type of Stem Cell

ChE Assistant Professor Ryan Koppes is developing methods of converting olfactory stem cells into Schwann Cells that can be used to repair nerve damage. He received a Spark Fund award from Northeastern’s Center for Research Innovation for this work.

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