Ryan Koppes

Assistant Professor,  Chemical Engineering

Contact

Social Media

Office

  • 339 Mugar
  • 617.373.8547

Lab

  • 111 Mugar
  • 617.373.8161

Research Focus

Neural interface technology, tissue engineering, and musculoskeletal biomechanics

About

Joined the Chemical Engineering Department in Fall 2015.

Education

  • PhD (2013) Rensselaer Polytechnic Institute, Biomedical Engineering
  • MS (2010) Rensselaer Polytechnic Institute, Biomedical Engineering, area of concentration: Muscle Tissue Engineering
  • BS (2008) Rensselaer Polytechnic Institute, Biomedical Engineering, area of concentration: Biomaterials

Honors & Awards

  • NIH National Institute of Biomedical Imaging and Bioengineering Trailblazer Award for New and Early Stage Investigators
  • Gilda Barbino Excellence in Mentoring Award

Professional Affiliations

  • American Society for Mechanical Engineers
  • Biophysical Society
  • Biomedical Engineering Society
  • Materials Research Society

Research Overview

Neural interface technology, tissue engineering, and musculoskeletal biomechanics

Laboratory for Neuromodulation and Neuromuscular Repair

We study the physical bridge between cells and electronics to improve nerve gap and prosthetic technologies. We’re also interested in neuron interactions with the heart to help relieve the healthcare burden of heart failure. Located in Boston, our group is able to join with other top universities to collaborate on ground breaking research.

Laboratory for Neuromodulation and Neuromuscular Repair

Selected Research Projects

College Research Initiatives

Selected Publications

  • Bindas, Adam J., Kulkarni, Subhash, Koppes, Ryan A., Koppes, Abigail N. (2021). Parkinson’s Disease and the Gut: Models of an Emerging Relationship. Acta Biomaterialia, 10.1016/J.ACTBIO.2021.03.071
  • Diaz Vera, David, Soucy, Jonathan R., Lee, Audrey, Koppes, Ryan A., Koppes, Abigail N. (2021). Light irradiation of peripheral nerve cells: Wavelength impacts primary sensory neuron outgrowth in vitro. Journal of Photochemistry and Photobiology B: Biology, 215,112105. 10.1016/J.JPHOTOBIOL.2020.112105
  • Ventre, Daniel M., Cluff, Avery, Gagnon, Christian, Diaz Vera, David, Koppes, Ryan A., Koppes, Abigail N. (2021). The effects of low intensity focused ultrasonic stimulation on dorsal root ganglion neurons and Schwann cells in vitro. Journal of Neuroscience Research, 99(1),374-391. 10.1002/JNR.24700
  • S. Hosic, W. Lake, E. Stas, R.A. Koppes, D.T. Breault, S.K. Murthy, A.N. Koppes, Cholinergic Activation of Primary Human Derived Intestinal Epithelium does not Ameliorate TNF-𝛼 Induced Injury, Cellular and Molecular Bioengineering, 2020
  • T. Torregrosa, S. Webster, C. Aghaizu, J. Soucy, C. Bertucci, L. Plant, A.N. Koppes, R.A. Koppes Cryopreservation and Functional Analysis of Cardiac Autonomic Neurons, Journal of Neuroscience Methods, 341, 2020, 108724
  • J. Snyder, C. Wang, A.Q. Zhang, Y. Li, J. Luchan, S. Hosic, R. Koppes, R.L. Carrier, A. Koppes, Materials and Microenvironments for Engineering the Intestinal Epithelium, Annals of Biomedical Engineering, 48, 2020, 1916–1940
  • S. Hosic, A. Bindas, M. Puzan, W. Lake, J. Soucy, F. Zhou, R.A. Koppes, D. Breault, S. Murthy, A.N. Koppes Rapid Prototyping of Multilayer Micro Physiological Systems, ACS Biomaterials Science & Engineering, 2020
  • K. Nichols, R. Koppes, A. Koppes, Recent Advancements in Micro Physiological Systems for Neural Development and Disease, Current Opinion in Biomedical Engineering, 14, 2020, 42-51
  • A.R. Spencer, E.S. Sani, J.R. Soucy, C.C. Corbet, A. Primebetova, R.A. Koppes, N. Annabi Bioprinting of a Cell-Laden Conductive Hydrogel Composite, ACS Applied Material Interfaces, 11(34), 2019, 30518-30533
  • J.R. Soucy, A.J. Bindas, A.N. Koppes, R.A. Koppes Instrumented Micro Physiological Systems for Real- Time Measurement and Manipulation of Cellular Electrochemical Processes, iScience, 21, 2019, 521-548

Faculty

Aug 19, 2022

Using Spark Fund Award to Regenerate Nerve Damage

ChE Assistant Professor Ryan Koppes is using the Spark Funds he received earlier this year to develop methods of converting olfactory stem cells into Schwann Cells that can be used to repair nerve damage.

Abigail Koppes working in a lab.

Faculty

Aug 16, 2022

Abigail Koppes: Advancing Technology, Treatment, and Diversity in Biomedical Engineering

Associate Professor Abigail Koppes, chemical engineering, began her career as a Future Faculty Fellow through Northeastern’s ADVANCE Office of Faculty Development. Today she is an associate professor, has two patents, and numerous young investigator recognitions.

professors posing in chemical engineering lab

Faculty

Aug 11, 2022

GelMA/MeTro Composites for Peripheral Nerve Repair

ChE Associate Professor Abigail Koppes and Assistant Professor Ryan Koppes were awarded a patent for creating “Gelatin/elastin composites for peripheral nerve repair.”

professors posing in chemical engineering lab

Faculty

Jun 09, 2022

Improving Fluidic Devices for Cell Cultures

ChE Assistant Professor Ryan Koppes and Associate Professor Abigail Koppes were awarded a patent for designing a “Fluidic device and method of assembling same.”

Undergraduate

May 18, 2022

Announcing Summer 2022 PEAK Experiences Awardees

Several engineering students and science students mentored by COE faculty are recipients of Northeastern’s Summer 2022 PEAK Experiences Awards.

Guohao Dai, Abby Koppes, Ryan Koppes

Faculty

Apr 04, 2022

$2M NASA Grant To Build Long Lasting Neurovascular Model

BioE Associate Professor Guohao Dai, ChE Associate Professor Abigail Koppes, and ChE Assistant Professor Ryan Koppes received a $2M grant from NASA titled “Bioengineer Long-lasting 3D Neurovascular Microphysiological System to Model Chronic Inflammation-mediated Neurodegeneration”.

Faculty

Feb 04, 2022

Announcing Spring 2022 PEAK Experiences Awardees

Several engineering students and science students mentored by COE faculty are recipients of Northeastern’s Spring 2022 PEAK Experiences Awards.

Undergraduate

Oct 12, 2021

Announcing Fall 2021 PEAK Experiences Awardees

Several engineering students and science students mentored by COE faculty are recipients of Northeastern’s Fall 2021 PEAK Experiences Awards. The PEAK Experiences Awards are a progressively structured sequence of opportunities designed to support learners as they continue climbing to new heights of achievement in undergraduate research and creative endeavor throughout their Northeastern journeys. ASCENT AWARDS […]

Faculty

Oct 12, 2021

Koppes Awarded $1.96M Early-Stage Investigator Grant from NIH

ChE Assistant Professor Ryan Koppes received a $1.96M NIH R35 MIRA (Maximizing Investigator’s Research Award) for Early Stage Investigators for “Engineering Multifaceted 3D Human Organ Platforms for Toxicity Testing.” This research will help to develop human organs-on-a-chip to improve drug toxicity testing.

Students

Jun 07, 2021

Summer 2021 PEAK Experiences Awardees

Congratulations to the COE student recipients of the Summer 2021 PEAK Experiences Awards. The PEAK Experiences Awards are a progressively structured sequence of opportunities designed to support learners as they continue climbing to new heights of achievement in undergraduate research and creative endeavor throughout their Northeastern journeys. BASE CAMP AWARDS Ana Salichs, E’22, “Colorimetric Assays […]

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