Bryan Spring

Affiliated Faculty, Bioengineering
Assistant Professor, Physics

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targeted photomedicine, biophysical microscopy and cancer biology

targeted photomedicine, biophysical microscopy and cancer biology

Multiplexed and Dynamically Targeted Photoimmunotherapy of Heterogeneous, Chemo-resistant Micrometastases Guided by Online In Vivo Optical Imaging of Cell-Surface Biomarkers
- – Principal Investigator, National Cancer Institute
Peering into Cancer Stem Cell Niches to Guide Suppression of Multiple Signaling Loop Pathways
- – Principal Investigator, Richard and Susan Smith Family Foundation

E.M. Kercher, S. Nath, I. Rizvi, B.Q. Spring Cancer Cell-Targeted and Activatable Photoimmunotherapy Spares T Cells in a 3D Co-Culture Model, Photochemistry and Photobiology, 96(2), 2020, 295–300
N. Davoudzadeh, G. Ducourthial, B.Q. Spring, Custom Fabrication and Mode-Locked Operation of a Femtosecond Fiber Laser for Multiphoton Microscopy, Scientific Reports, 9, 2019, 4233
B.Q. Spring, R.B. Sears, L.Z. Zheng, Z.Mai, R. Watanabe, M.E. Sherwood, D.A. Schoenfeld, B.W. Pogue, S.P. Pereira, E. Villa, T. Hasan, A Photoactivable Multi-Inhibitor Nanoliposome for Tumour Control and Simultaneous Inhibition of Treatment Escape Pathways, Nature Nanotechnology, 11(4), 2016, 378
B.Q. Spring, A.O. Abu-Yousif, A. Palanisami, I. Rizvi, X. Zheng, Z. Mai, S. Anbil, R.B. Sears, L.B. Mensah, R. Goldschmidt, S.S. Erdem, E. Oliva E, T. Hasan Selective Treatment and Monitoring of Disseminated Cancer Micrometastases in Vivo using Dual-Function, Activatable Immunoconjugates, Proceedings of the National Academy of Sciences of the United States of America, 111(10), 2014, E933–E942