Bryan Spring
Affiliated Faculty, Bioengineering
Assistant Professor, Physics
Contact
- b.spring@northeastern.edu
- 111 DA
360 Huntington Avenue
Boston, Massachusetts 02115
Office
- 617.373.5303
Research Focus
targeted photomedicine, biophysical microscopy and cancer biology
Education
- PhD, University of Illinois 2008
Honors & Awards
- Smith Family Awards Program for Excellence in Biomedical Research
- The National Cancer Institute Transition Career Development Award
Research Overview
targeted photomedicine, biophysical microscopy and cancer biology
Selected Research Projects
- Multiplexed and Dynamically Targeted Photoimmunotherapy of Heterogeneous, Chemo-resistant Micrometastases Guided by Online In Vivo Optical Imaging of Cell-Surface Biomarkers
- – Principal Investigator, National Cancer Institute
- Peering into Cancer Stem Cell Niches to Guide Suppression of Multiple Signaling Loop Pathways
- – Principal Investigator, Richard and Susan Smith Family Foundation
Selected Publications
- E.M. Kercher, S. Nath, I. Rizvi, B.Q. Spring Cancer Cell-Targeted and Activatable Photoimmunotherapy Spares T Cells in a 3D Co-Culture Model, Photochemistry and Photobiology, 96(2), 2020, 295–300
- N. Davoudzadeh, G. Ducourthial, B.Q. Spring, Custom Fabrication and Mode-Locked Operation of a Femtosecond Fiber Laser for Multiphoton Microscopy, Scientific Reports, 9, 2019, 4233
- B.Q. Spring, R.B. Sears, L.Z. Zheng, Z.Mai, R. Watanabe, M.E. Sherwood, D.A. Schoenfeld, B.W. Pogue, S.P. Pereira, E. Villa, T. Hasan, A Photoactivable Multi-Inhibitor Nanoliposome for Tumour Control and Simultaneous Inhibition of Treatment Escape Pathways, Nature Nanotechnology, 11(4), 2016, 378
- B.Q. Spring, A.O. Abu-Yousif, A. Palanisami, I. Rizvi, X. Zheng, Z. Mai, S. Anbil, R.B. Sears, L.B. Mensah, R. Goldschmidt, S.S. Erdem, E. Oliva E, T. Hasan Selective Treatment and Monitoring of Disseminated Cancer Micrometastases in Vivo using Dual-Function, Activatable Immunoconjugates, Proceedings of the National Academy of Sciences of the United States of America, 111(10), 2014, E933–E942
Apr 27, 2023
FY24 TIER 1 Award Recipients
Twelve COE faculty and affiliates were recipients of FY24 TIER 1 Interdisciplinary Research Seed Grants for 11 different projects.
Apr 27, 2023
Announcing Summer 2023 PEAK Experiences Awardees
Several engineering students and science students mentored by COE faculty are recipients of Northeastern’s Summer 2023 PEAK Experiences Awards. They will be pursuing a diverse set of projects, including a study of a pathogen that haunts hospitals, an examination of segregationist rhetoric in Boston newspapers, and an analysis of creativity in music.