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Vladimir P. Torchilin

Affiliated Faculty,  Chemical Engineering
University Distinguished Professor and Director,  Pharmaceutical Sciences

Contact

Office

  • 140 The Fenway, Room 211/214
  • 617.373.3206

Research Focus

Drug delivery and targeting; Drug carriers; Pharmaceutical biotechnology; Experimental cancer immunology; Nanomedicine; Pharmaceutical carriers; Liposomes and micelles

Honors & Awards

  • 1982 Lenin Prize of the USSR in Science and Technology (the highest scientific award in the former USSR)
  • 2002 Fellow, American Institute for Medical and Biological Engineering
  • 2002 Member, European Academy of Sciences
  • 2003 Fellow, American Association of Pharmaceutical Scientists (AAPS)
  • 2003 ATOMS Research Excellence in Mentorship Award, National Institute of General Medical Sciences
  • 2005 President, Controlled Release Society
  • 2005 Research Achievements Award in Pharmaceutics and Drug Delivery, AAPS
  • 2005 The Joy Goodwin Lecturer, Auburn University
  • 2006 2006 CRS-Baxter Healthcare Outstanding Parenteral Drug Delivery Award
  • 2006 The Massachusetts Technology Transfer Center 2006 Investigation Award
  • 2007 Research Achievements Award from the World Pharmaceutical Congress, Amsterdam
  • 2008 Prestige Lectureship, University of Montreal
  • 2008 Horizons in Nanotechnology Lectureship, Emory University
  • 2009 University of North Carolina-Eisai Distinguished Lectureship in Drug Delivery
  • 2009 The Meritorious Paper AAPS Journal 2008 Award
  • 2009 2009 International Journal of Nanomedicine Distinguished Scientist Award
  • 2010 Avis Distinguished Visiting Professor Lectureship, University of Tennessee, Memphis
  • 2010 Founders Award, Controlled Release Society
  • 2012 Alec Bangham Life Achievement Award
  • 2013 Journal of Drug Targeting Life Time Achievement Award
  • 2013 Blaise Pascal Medal in Biomedicine from the European Academy of Sciences
  • 2015 Chair, XX International Symposium on Microencapsulation, Boston
  • 2015 European Journal of Pharmaceutics and Biopharmaceutics best paper award for 2014
  • 2016 International Chair of Therapeutic Innovation, LabEx LERMIT, France
  • 2017 Outstanding Excellence Award from Pharmaceutica 2017, London, UK
  • 2017 Albert Nelson Marquis Lifetime Achievement Award
  • 2018 President, BIONANOTOX, Greece
  • 2018 Conference Chair, Material Science-2018, Amsterdam, The Netherlands
  • 2019 Highly Cited Researcher from Thomson Reuters

Research Overview

Drug delivery and targeting; Drug carriers; Pharmaceutical biotechnology; Experimental cancer immunology; Nanomedicine; Pharmaceutical carriers; Liposomes and micelles

Dendrimers as pharmaceutical carriers; Co-delivery of siRNA and chemotherapeutics for multidrug resistant cancer; Hypoxia-mediated drug delivery

Research Centers and Institutes

  • Director, Center for Pharmaceutical Biotechnology and Nanomedicine

Selected Publications

  • Filipczak N, Jaromin A, Piwoni A, Mahmud M, Sarisozen C, Torchilin V, Gubernator J. A Triple Co-Delivery Liposomal Carrier That Enhances Apoptosis via an Intrinsic Pathway in Melanoma Cells. Cancers (Basel). 2019 Dec 9;11(12)
  • Zhang X, Pan J, Yao M, Palmerston Mendes L, Sarisozen C, Mao S, Torchilin VP, Charge reversible hyaluronic acid-modified dendrimer-based nanoparticles for siMDR-1 and doxorubicin co-delivery. Eur. J. Pharm. Biopharm. 154, 43-49, 2020.
  • Khan MM, Madni A, Filipczak N, Pan J, Rehman M, Rai N, Attia SA, Torchilin VP, Folate targeted lipid chitosan hybrid nanoparticles for enhanced anti-tumor efficacy. Nanomedicine. 2020; 28:102228.
  • Pan J, Attia SA, Subhan MA, Filipczak N, Mendes LP, Li X, Kishan Yalamarty SS, Torchilin VP, Monoclonal Antibody 2C5-Modified Mixed Dendrimer Micelles for Tumor-Targeted Codelivery of Chemotherapeutics and siRNA. Mol. Pharm. 17, 1638-1647, 2020.
  • Joshi U, Filipczak N, Khan MM, Attia SA, Torchilin V, Hypoxia-sensitive micellar nanoparticles for co-delivery of siRNA and chemotherapeutics to overcome multi-drug resistance in tumor cells. Int J Pharm. 2020; 590:119915.
  • Mendes LP, Rostamizadeh K, Gollomp K, Myerson JW, Marcos-Contreras OA, Zamora M, Luther E, Brenner JS, Filipczak N, Li X, Torchilin VP, Monoclonal antibody 2C5 specifically targets neutrophil extracellular traps.  MAbs. 2020; 12(1):1850394