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EXPLORE NORTHEASTERN

Paul Whitford

Affiliated Faculty,  Bioengineering
Assistant Professor,  Physics

Contact

Office

  • 617.373.2952

Research Focus

dynamics of large-scale molecular machines, working to identify the physical principles that guide biomolecular dynamics, using molecular simulation approaches to interpret experimental data from a wide range of techniques, including biochemical, small-angle X-ray scattering and cryogenic electron microscopy

Research Focus

dynamics of large-scale molecular machines, working to identify the physical principles that guide biomolecular dynamics, using molecular simulation approaches to interpret experimental data from a wide range of techniques, including biochemical, small-angle X-ray scattering and cryogenic electron microscopy

Research Initiatives

Advancing Nanotechnology through Innovation in Materials Engineering
Integrated Modeling, Inference, and Computing

Selected Publications

  • M. Levi, K. Nguyen, L. Dukaye, P.C. Whitford, Quantifying the relationship between single-molecule probes and subunit rotation in the ribosome. Biophysical Journal, 113, 2017, 2777-2786
  • P. Waduge, R. Hu, P. Bandarkar, H. Yamazaki, B. Cressiot, Q. Zhao, P.C. Whitford, M. Wanunu, Nanopore-based Measurements of Protein Size, Fluctuations, and Conformational Changes. ACS Nano. 11, 2017, 5706-5716
  • Nguyen, P.C. Whitford, Steric Interactions Lead to Collective Head Tilting During mRNAtRNA Translocation on the Ribosome. Nature Communications. 7, 2016, 10586
  • J. K. Noel, P.C. Whitford, How EF-Tu Can Contribute to Efficient Proofreading of aa-tRNA by the Ribosome, Nature Communications 7, 2016, 13314
  • P.C. Whitford, Disorder Guides Protein Function. Proceedings of the National Academy of Sciences USA, 110, 2013, 7114-7115