Mohammad Abbas Yaseen

Assistant Professor,  Bioengineering

Contact

Office

  • 617.373.8584

Research Focus

Advanced microscopy for minimally invasive, in vivo characterization of brain function

Education

  • PhD, Rice University, Bioengineering, 2008
  • BS, Johns Hopkins University, Biomedical and Electrical Engineering, 2002

Professional Affiliations

  • Society for Neuroscience

Research Overview

Advanced microscopy for minimally invasive, in vivo characterization of brain function

Optical Microscopy & Neuro-Imaging Lab

The OMNI Lab strives to develop and apply high-resolution optical technologies to investigate brain function in rodent models of human disease. Specifically, we apply advanced optical microscopy methods to investigate metabolic and immune features during healthy brain function and their disease-related alterations. The overarching goal of these efforts is to characterize the etiologies of debilitating brain pathologies, including stroke and neurodegenerative diseases. Understanding at the cellular level how these pathologies advance within living brains will ultimately help identify precise and robust biomarkers for diagnosis and therapy.

OMNI Lab

Selected Research Projects

  • Relating neuroimmune and neurovascular alterations during Alzheimer’s Disease progression
    • Principal Investigator, National Institute of Health

Selected Publications

  • B. Li, R. Ohtomo, M. Thunemann, S.R. Adams, J. Yang, B. Fu, M.A. Yaseen, C. Ran, J.R. Polimeni, D.A. Boas, Devor, E.H. Lo, K. Arai, S. Sakadžić, Two-photon Microscopic Imaging of Capillary Red Blood Cell Flux in Mouse Brain Reveals Vulnerability of Cerebral White Matter to Hypoperfusion, Journal of Cerebral Blood Flow and Metabolism, 40(3), 2020, 501-512
  • Li, T.V. Esipova, I. Sencan, K. Kilic, B.Y. Fu, M. Desjardins, M. Moeini, S. Kura, M.A. Yaseen, F. Lesage, L. Ostergaard, A. Devor, D.A. Boas, S.A. Vinogradov, S. Sakadžić, More Homogeneous Capillary Flow and Oxygenation in Deeper Cortical Layers Correlate with Increased Oxygen Extraction, ELife, 8, 2019, e42299
  • C.A. Gomez, S. Sakadzic, J. Sutin, W. Wu, B. Fu, D.A. Boas, M.A. Yaseen, Phasor Analysis of NADH HIM Identifies Pharmacological Disruptions to Mitochondrial Metabolic Processes in the Rodent Cerebral Cortex, PLoS One, 13(3), 2018, e0194578

Faculty

Feb 04, 2022

Announcing Spring 2022 PEAK Experiences Awardees

Several engineering students and science students mentored by COE faculty are recipients of Northeastern’s Spring 2022 PEAK Experiences Awards.

Mohammad Abbas Yaseen

Faculty

Jan 03, 2020

New Faculty Spotlight: Mohammad Abbas Yaseen

Mohammad Abbas Yaseen joins the Bioengineering department in January 2020 as an Assistant Professor.

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