Bajpayee’s Lab Research Featured on Cover of Biomaterials Science
Research conducted in BioE Associate Professor Ambika Bajpayee’s Molecular Bioelectrostatics and Drug Delivery Lab that focuses on oral delivery of gene therapeutics was featured on the front cover of Biomaterials Science. Students conducting the research are Chenzhen Zhang, PhD’23, and Hengli Zhang, PhD’25.
Recent research in BioE Associate Professor Ambika Bajpayee’s lab was featured on the front cover of Biomaterials Science. The research, “Milk exosomes anchored with hydrophilic and zwitterionic motifs enhance mucus permeability for applications in oral gene delivery,” develops mucus penetrating milk exosomes for oral delivery of gene therapeutics, which currently are limited to systemic administration. The lab configured the surface of milk derived exosomes for easy anchoring of electrically charged and hydrophilic motifs that enhanced their penetration through the mucosal barrier enabling targeting of the intestinal epithelial cells. The research was led by Bajpayee’s Molecular Bioelectrostatics and Drug Delivery Laboratory graduate students, Chenzhen Zhang, PhD’23, and Hengli Zhang, PhD’25. Additionally, ChE Professor Rebecca Carrier collaborated with the team.