Sensitive protein analysis with plexDIA
Technology for sensitive protein analysis developed in the laboratory of BioE Associate Professor and Allen Distinguished Investigator Nikolai Slavov was highlighted in a Nature Methods article Sensitive protein analysis with plexDIA.
High-throughput proteomic analysis of low-volume or single-cell samples continue to be limited in depth and throughput. Until now, the throughput of mass spectrometry (MS)-based sensitive protein analysis has been increased either by chemical labeling or by simultaneous analysis of multiple peptides. The research group of Nikolai Slavov from Northeastern University and their collaborators have combined the two strategies to develop plexDIA.