Mansoor Amiji

University Distinguished Professor,  Pharmaceutical Sciences
University Distinguished Professor,  Chemical Engineering
Affiliated Faculty,  Bioengineering

Contact

Office

  • 140 The Fenway, Room 165
  • 617.373.3137

Research Focus

Polymeric biomaterials, drug delivery systems, nanomedical technologies

Education

  • BS, Pharmacy (magna cum laude), Northeastern University
  • PhD, Pharmaceutics, Purdue University

Honors & Awards

  • T. Nagai Award, Controlled Release Society
  • Fellow, America Association of Pharmaceutical Scientists (AAPS)
  • Fellow, Controlled Release Society
  • Charivate Analytics Highly Cited Author (top 1%)
  • Distinguished Alumni Award, Purdue University College of Pharmacy

Professional Affiliations

  • American Association of Pharmaceutical Scientists, Fellow
  • Controlled Release Society, Fellow

Research Overview

Polymeric biomaterials, drug delivery systems, nanomedical technologies

Selected Research Projects

  • Development and Validation of a Novel Cas13a and Nanoparticle Guide-RNA Delivery System that Allows Precise Ablation of Host Macrophage Populations in a Humanized Mouse Model
    • – Principal Investigator, Jackson Laboratories on a National Institutes of Health
  • Direct CNS Delivery System for BDNF AntagoNATs using Heterotopic Mucosal Grafting for the Treatment of Parkinson’s Disease
    • – Principal Investigator, National Institutes of Health

Department Research Areas

Selected Publications

  • J. Bae, N. Parayath, W. Ma, M. Amiji, N. Munshi, K. Anderson, Bcma Peptide Engineered Nanoparticles Enhance Induction and Function of Antigen Specific Cd8+ Cytotoxic T Lymphocytes Against Multiple Myeloma, Nature – Leukemia, 34, 2020, 210–223
  • N.N. Parayath, S. Padmakumar, M. Amiji, Extracellular Vesicle-Mediated Nucleic Acid Transfer and Reprogramming in the Tumor Microenvironment, Cancer Letters, 482(10), 2020, 33-43
  • G. Ahmad, G. Mackenzie, J. Egan, M. Amiji, Dha-Sbt-1214 Taxoid Nanoemulsion and Anti-Pd-L1 Antibody Combination Therapy Enhances Antitumor Efficacy in a Syngeneic Pancreatic Adenocarcinoma Model, Molecular Cancer Therapeutics, 18(11), 2019, 961-1972
  • D. Chen, N. Parayath, S. Ganesh, W. Wang, M. Amiji, Role of Apolipoprotein-and Vitronectin-Enriched Protein Corona on Lipid Nanoparticles for in Vivo Targeted Delivery and Transfection of Oligonucleotides in Murine Tumor Models, Nanoscale, 11, 2019, 18806–18824

Faculty

Sep 20, 2022

Fall 2022 Spark Fund Awardees

Bouve/ChE University Distinguished Professor Mansoor Amiji, ChE Assistant Professor Sara Hashmi, ECE Professor Purnima Ratilal-Makris, and MIE Assistant Professor Mohsen Moghaddam are recipients of the Fall 2022 Spark Fund Awards. The goal of the award is to advance a technology or suite of technologies from academia towards commercialization.

Jul 06, 2022

Announcing the new MS in Pharmaceutical Engineering at Northeastern University

The College of Engineering and Bouve College of Health Sciences at Northeastern University are offering a new Master of Science in Pharmaceutical Engineering. Both colleges began to recognize the growing need in the pharmaceutical sector for people that have both an engineering background as well as understand the regulatory environment of the pharmaceutical industry. “The […]

Faculty

Dec 23, 2021

COE Professors Selected in Stanford University List of Top 2% Scientists Worldwide

The following COE professors are among the top scientists worldwide selected by Stanford University representing the top 2 percent of the most-cited scientists with single-year impact in various disciplines. The selection is based on the top 100,000 by c-score (with and without self-citations) or a percentile rank of 2% or above. The list below includes […]

Faculty

Apr 20, 2021

FY22 TIER 1 Award Recipients

Congratulations to the 17 COE faculty and affiliates who were recipients of FY22 TIER 1 Interdisciplinary Research Seed Grants for 11 different projects.

professor working in lab on project

Faculty

Feb 12, 2021

Developing Technology to Optimally Detect and Count Circulating Tumor Cells without Drawing Blood

BioE Professor Mark Niedre and Bouve/ChE Professor Mansoor Amiji are using their recent NCI/NIH grant to detect circulating tumor cells in the blood.

Mark Niedre and Mansoor Amiji

Faculty

Jan 07, 2021

Niedre and Amiji Receive National Cancer Institute Award

Bioengineering Professor and Associate Chair Mark Niedre and Bouve/ChE Distinguished Professor Mansoor Amiji received a 2-year, $400K grant titled “Fluorescence Molecular In Vivo Liquid Biopsy of Circulating Tumor Cells” from the National Cancer Institute and National Institutes of Health.

medical worker putting needle in vaccination container

Faculty

Nov 12, 2020

Will the Vaccine Be Effective?

Bouve/ChE University Distinguished Professor Mansoor Amiji explains how Pfizer’s new vaccine for COVID will work. This vaccine could prevent COVID-19 in 9 out of 10 people. But how does it work? On Monday, the pharmaceutical company Pfizer announced that its COVID-19 vaccine is more than 90 percent effective at preventing the disease according to preliminary […]

needle being put into vaccine tube

Faculty

Oct 05, 2020

Creating an Effective Vaccine

Bouve/ChE University Distinguished Professor Mansoor Amiji explains why it takes so long to create a safe and effective vaccine for COVID-19.

Faculty

Mar 27, 2019

Amiji Awarded Distinguished Alumni Award

Bouve/ChE Professor Mansoor Amiji will receive the 2019 Distinguished Alumni Award from Purdue University’s College of Pharmacy on April 5, 2019, in recognition of his outstanding achievements in professional and scientific endeavors.

Faculty

Jul 24, 2017

Northeastern Researchers Contribute to Methodist DeBakey Cardiovascular Journal

The Methodist DeBakey Cardiovascular Journal (MDCVJ) reports on leading edge research, diagnosis, and treatments from specialists at the Houston Methodist DeBakey Heart & Vascular Center and other invited contributors. In Volume 12, Number 3 (July-September 2016), numerous faculty and one PhD student had their research featured in the journal. Nucleic Acid Delivery for Endothelial Dysfunction in […]

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