Mansoor Amiji

University Distinguished Professor,  Pharmaceutical Sciences
University Distinguished Professor,  Chemical Engineering
Affiliated Faculty,  Bioengineering

Contact

Office

  • 140 The Fenway, Room 165
  • 617.373.3137

Related Links

Research Focus

Polymeric biomaterials, drug delivery systems, nanomedical technologies

Education

  • BS, Pharmacy (magna cum laude), Northeastern University
  • PhD, Pharmaceutics, Purdue University

Honors & Awards

  • T. Nagai Award, Controlled Release Society
  • Fellow, America Association of Pharmaceutical Scientists (AAPS)
  • Fellow, Controlled Release Society
  • Charivate Analytics Highly Cited Author (top 1%)
  • Distinguished Alumni Award, Purdue University College of Pharmacy

Professional Affiliations

  • American Association of Pharmaceutical Scientists, Fellow
  • Controlled Release Society, Fellow

Research Overview

Polymeric biomaterials, drug delivery systems, nanomedical technologies

Selected Research Projects

  • Combination Strategy for the Treatment of Advanced Pancreatic Cancer
    • – Principal Investigator, National Institutes of Health
  • Development and Validation of a Novel Cas13a and Nanoparticle Guide-RNA Delivery System that Allows Precise Ablation of Host Macrophage Populations in a Humanized Mouse Model
    • – Principal Investigator, Jackson Laboratories on a National Institutes of Health
  • Direct CNS Delivery System for BDNF AntagoNATs using Heterotopic Mucosal Grafting for the Treatment of Parkinson’s Disease
    • – Principal Investigator, National Institutes of Health

Department Research Areas

Selected Publications

  • J. Bae, N. Parayath, W. Ma, M. Amiji, N. Munshi, K. Anderson, Bcma Peptide Engineered Nanoparticles Enhance Induction and Function of Antigen Specific Cd8+ Cytotoxic T Lymphocytes Against Multiple Myeloma, Nature – Leukemia, 34, 2020, 210–223
  • N.N. Parayath, S. Padmakumar, M. Amiji, Extracellular Vesicle-Mediated Nucleic Acid Transfer and Reprogramming in the Tumor Microenvironment, Cancer Letters, 482(10), 2020, 33-43
  • G. Ahmad, G. Mackenzie, J. Egan, M. Amiji, Dha-Sbt-1214 Taxoid Nanoemulsion and Anti-Pd-L1 Antibody Combination Therapy Enhances Antitumor Efficacy in a Syngeneic Pancreatic Adenocarcinoma Model, Molecular Cancer Therapeutics, 18(11), 2019, 961-1972
  • D. Chen, N. Parayath, S. Ganesh, W. Wang, M. Amiji, Role of Apolipoprotein-and Vitronectin-Enriched Protein Corona on Lipid Nanoparticles for in Vivo Targeted Delivery and Transfection of Oligonucleotides in Murine Tumor Models, Nanoscale, 11, 2019, 18806–18824

Faculty

Feb 27, 2024

Avoiding Safety Risks for mRNA Therapeutics

Bouvé/ChE University Distinguished Professor Mansoor Amiji co-authored a paper in Nature Reviews Drug Discovery outlining several strategies to check for toxicity at the preclinical level of mRNA therapeutics to ensure patient safety.

Faculty

Jan 17, 2024

New Cancer Vaccines Could Provide Beneficial Alternative Therapy

Bouvé/ChE University Distinguished Professor Mansoor Amiji sees the promise of new cancer vaccines amid encouraging results from treatment studies.

Faculty

Dec 07, 2023

2023 Stanford University Annual Assessment of Author Citations

The following COE professors are among the top scientists worldwide selected by Stanford University representing the top 2% of the most-cited scientists with single-year impact in various disciplines. The selection is based on the top 100,000 by c-score (with and without self-citations) or a percentile rank of 2% or above. The list below includes those […]

Faculty

Nov 03, 2023

Understanding the Efficacy of the COVID-19 Vaccine

Bouve/ChE University Distinguished Professor Mansoor Amiji explains how the COVID-19 vaccine is designed to prevent severe illness, hospitalization, and death, rather than to eliminate infection entirely.

Faculty

Mar 02, 2023

New Treatments for Pancreatic Cancer

Bouve/ChE University Distinguished Professor Mansoor Amiji is working with UC Davis and drug developer TargaGenix to create new treatments for pancreatic cancer.

Mansoor Amiji

Faculty

Dec 27, 2022

Everything to Know About the Common Cold and How to Treat Symptoms

“Our study is really focused on prevention, that initial exposure and how to enhance your defenses,” said lead author Mansoor Amiji, professor of pharmaceutical sciences at Northeastern University. (Featured in USA Today)

Faculty

Nov 02, 2022

2022 Stanford University Annual Assessment of Author Citations

The following COE professors are among the top scientists worldwide selected by Stanford University representing the top 2 percent of the most-cited scientists with single-year impact in various disciplines. The selection is based on the top 100,000 by c-score (with and without self-citations) or a percentile rank of 2% or above. The list below includes […]

Faculty

Sep 20, 2022

Spring 2022 Spark Fund Awardees

Bouve/ChE University Distinguished Professor Mansoor Amiji, ChE Assistant Professor Sara Hashmi, ECE Professor Purnima Ratilal-Makris, and MIE Assistant Professor Mohsen Moghaddam are recipients of the Spring 2022 Spark Fund Awards. The goal of the award is to advance a technology or suite of technologies from academia towards commercialization.

In the Media

Aug 26, 2022

Moderna Sues Pfizer and BioNTech over COVID Vaccine Patents

“We’re seeing a lot of lawsuits related to mRNA vaccines right now, so I wasn’t surprised about this particular lawsuit,” said Mansoor Amiji, a professor of pharmaceutical sciences and chemical engineering at Northeastern University. (Featured in The Boston Globe)

Jul 06, 2022

Announcing the new MS in Pharmaceutical Engineering at Northeastern University

The College of Engineering and Bouve College of Health Sciences at Northeastern University are offering a new Master of Science in Pharmaceutical Engineering. Both colleges began to recognize the growing need in the pharmaceutical sector for people that have both an engineering background as well as understand the regulatory environment of the pharmaceutical industry. “The […]

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