Mansoor Amiji

University Distinguished Professor,  Pharmaceutical Sciences
University Distinguished Professor,  Chemical Engineering
Affiliated Faculty,  Bioengineering

Contact

Office

  • 140 The Fenway, Room 165
  • 617.373.3137

Research Focus

Polymeric biomaterials, drug delivery systems, nanomedical technologies

Education

  • BS, Pharmacy (magna cum laude), Northeastern University
  • PhD, Pharmaceutics, Purdue University

Honors & Awards

  • T. Nagai Award, Controlled Release Society
  • Fellow, America Association of Pharmaceutical Scientists (AAPS)
  • Fellow, Controlled Release Society

Professional Affiliations

  • American Association of Pharmaceutical Scientists, Fellow
  • Controlled Release Society, Fellow

Research Overview

Polymeric biomaterials, drug delivery systems, nanomedical technologies

Selected Research Projects

  • Development and Validation of a Novel Cas13a and Nanoparticle Guide-RNA Delivery System that Allows Precise Ablation of Host Macrophage Populations in a Humanized Mouse Model
    • – Principal Investigator, Jackson Laboratories on a National Institutes of Health
  • Direct CNS Delivery System for BDNF AntagoNATs using Heterotopic Mucosal Grafting for the Treatment of Parkinson’s Disease
    • – Principal Investigator, National Institutes of Health

Department Research Areas

Selected Publications

  • J. Bae, N. Parayath, W. Ma, M. Amiji, N. Munshi, K. Anderson, Bcma Peptide Engineered Nanoparticles Enhance Induction and Function of Antigen Specific Cd8+ Cytotoxic T Lymphocytes Against Multiple Myeloma, Nature – Leukemia, 34, 2020, 210–223
  • N.N. Parayath, S. Padmakumar, M. Amiji, Extracellular Vesicle-Mediated Nucleic Acid Transfer and Reprogramming in the Tumor Microenvironment, Cancer Letters, 482(10), 2020, 33-43
  • G. Ahmad, G. Mackenzie, J. Egan, M. Amiji, Dha-Sbt-1214 Taxoid Nanoemulsion and Anti-Pd-L1 Antibody Combination Therapy Enhances Antitumor Efficacy in a Syngeneic Pancreatic Adenocarcinoma Model, Molecular Cancer Therapeutics, 18(11), 2019, 961-1972
  • D. Chen, N. Parayath, S. Ganesh, W. Wang, M. Amiji, Role of Apolipoprotein-and Vitronectin-Enriched Protein Corona on Lipid Nanoparticles for in Vivo Targeted Delivery and Transfection of Oligonucleotides in Murine Tumor Models, Nanoscale, 11, 2019, 18806–18824

Faculty

Feb 12, 2021

Developing Technology to Optimally Detect and Count Circulating Tumor Cells without Drawing Blood

BioE Professor Mark Niedre and Bouve/ChE Professor Mansoor Amiji are using their recent NCI/NIH grant to detect circulating tumor cells in the blood.

Faculty

Jan 07, 2021

Niedre and Amiji Receive National Cancer Institute Award

Bioengineering Professor and Associate Chair Mark Niedre and Bouve/ChE Distinguished Professor Mansoor Amiji received a 2-year, $400K grant titled “Fluorescence Molecular In Vivo Liquid Biopsy of Circulating Tumor Cells” from the National Cancer Institute and National Institutes of Health.

Faculty

Nov 12, 2020

Will the Vaccine Be Effective?

Bouve/ChE University Distinguished Professor Mansoor Amiji explains how Pfizer’s new vaccine for COVID will work. This vaccine could prevent COVID-19 in 9 out of 10 people. But how does it work? On Monday, the pharmaceutical company Pfizer announced that its COVID-19 vaccine is more than 90 percent effective at preventing the disease according to preliminary […]

Faculty

Oct 05, 2020

Creating an Effective Vaccine

Bouve/ChE University Distinguished Professor Mansoor Amiji explains why it takes so long to create a safe and effective vaccine for COVID-19.

Faculty

Mar 27, 2019

Amiji Awarded Distinguished Alumni Award

Bouve/ChE Professor Mansoor Amiji will receive the 2019 Distinguished Alumni Award from Purdue University’s College of Pharmacy on April 5, 2019, in recognition of his outstanding achievements in professional and scientific endeavors.

Faculty

Jul 24, 2017

Northeastern Researchers Contribute to Methodist DeBakey Cardiovascular Journal

The Methodist DeBakey Cardiovascular Journal (MDCVJ) reports on leading edge research, diagnosis, and treatments from specialists at the Houston Methodist DeBakey Heart & Vascular Center and other invited contributors. In Volume 12, Number 3 (July-September 2016), numerous faculty and one PhD student had their research featured in the journal. Nucleic Acid Delivery for Endothelial Dysfunction in […]

Jun 28, 2017

Young Scholar Program Provides Experience-Based Learning for Future Scientists and Engineers

The Center for STEM Education kicked off its 2017 Young Scholars Program on June 26, 2017, with 26 budding scientists and engineers from high schools at a variety of cities and towns in the Greater Boston area.

Jul 12, 2016

ChE Chair and Professor Webster and Affiliated Professor Amiji give invited talks on Nanomedicine in Austria

ChE Chair & Professor Tom Webster and Affiliated Professor Mansoor Amiji gave invited talks last week at the Nanotechnology in Medicine Conference: From Molecules to Humans Conference last week in Austria. The conference coalesced leaders in the field of nanomedicine to discuss where the field has been and where it is headed.

Mar 22, 2016

FY17 TIER 1 Award Recipients

23 COE faculty and affiliates were recipients of FY17 TIER 1 Interdisciplinary Research Seed Grants for 12 different projects representing over $600K dollars of investment in research.

Oct 16, 2015

Webster Editor of On-line Nanomedicine Book

Che Professor & Chair Thomas Webster was the editor for the new on-line book Nanomedicine published by Henry Stewart Talks. The book contains 16 chapters by NEU professors Mansoor Amiji (Pharm and ChemE), Ed Goluch (ChemE), Ke Zhang (Chemistry), and Mauro Ferrari (Houston Methodist Research Institute and ChemE).

View All Related News