Chiara Bellini

Assistant Professor,  Bioengineering

Contact

Office

  • 228 ISEC
  • 617.373.2550

Research Focus

Diseases of the cardiovascular system; effects of cellmediated growth and remodeling processes on tissue and organ mechanics

Education

  • 2012 PhD in Biomedical Engineering, The University of Calgary
  • 2008 MSc in Biomedical Engineering, Politecnico di Milano, Italy
  • 2005 BSc in Biomedical Engineering, Politecnico di Milano, Italy

Research Overview

Diseases of the cardiovascular system; effects of cellmediated growth and remodeling processes on tissue and organ mechanics

Selected Research Projects

  • Evaluation of Aortic Stiffening as an Early Indicator of Anthracycline-Induced Cardiotoxicity
    • – Principal Investigator, National Institute of Health
  • Health Consequences Following Acute and Chronic Firefighter Exposure to Wildland Fire Smoke
    • – Principal Investigator, Department of Homeland Security, Federal Emergency Management Agency
  • Pulmonary and Cardiovascular Health Consequences Following Electronic Cigarette Exposure
    • – Principal Investigator, National Institute of Health

Selected Publications

  • Augustin, Christoph M., Fastl, Thomas E., Neic, Aurel, Bellini, Chiara, Whitaker, John, Rajani, Ronak, O’Neill, Mark D., Bishop, Martin J., Plank, Gernot, Niederer, Steven A. (2020). The impact of wall thickness and curvature on wall stress in patient-specific electromechanical models of the left atrium. Biomechanics and Modeling in Mechanobiology, 19(3),1015-1034. 10.1007/S10237-019-01268-5
  • Boytard, Ludovic, Hadi, Tarik, Silvestro, Michele, Qu, Hengdong, Kumpfbeck, Andrew, Sleiman, Rayan, Fils, Kissinger Hyppolite, Alebrahim, Dornazsadat, Boccalatte, Francesco, Kugler, Matthias, Corsica, Annanina, Gelb, Bruce E., Jacobowitz, Glenn, Miller, George, Bellini, Chiara, Oakes, Jessica, Silvestre, Jean-Sébastien, Zangi, Lior, Ramkhelawon, Bhama (2020). Lung-derived HMGB1 is detrimental for vascular remodeling of metabolically imbalanced arterial macrophages. Nature Communications, 11(1). 10.1038/S41467-020-18088-2
  • Dong, Melody, Oakes, Jessica M., Bellini, Chiara, Rayz, Vitaliy L., LaDisa, John F., Parker, Dave, Wilson, Nathan M., Shadden, Shawn C., Marsden, Alison L., Goergen, Craig J., Boster, Kimberly A. Stevens (2020). Integrated Image-Based Computational Fluid Dynamics Modeling Software as an Instructional Tool. Journal of Biomechanical Engineering, 142(11). 10.1115/1.4047479
  • Farra, Yasmeen M., Eden, Matthew J., Coleman, James R., Kulkarni, Praveen, Ferris, Craig F., Oakes, Jessica M., Bellini, Chiara (2020). Acute neuroradiological, behavioral, and physiological effects of nose-only exposure to vaporized cannabis in C57BL/6 mice. Inhalation Toxicology, 32(5),200-217. 10.1080/08958378.2020.1767237
  • Fitzgerald, Jessica E., Byrd, Brook K., Patil, Roshani A., Strawbridge, Rendall R., Davis, Scott C., Bellini, Chiara, Niedre, Mark (2020). Heterogeneity of circulating tumor cell dissemination and lung metastases in a subcutaneous Lewis lung carcinoma model. Biomedical Optics Express, 11(7),3633. 10.1364/BOE.395289
  • Mueller, Amy V., Eden, Matthew J., Oakes, Jessica M., Bellini, Chiara, Fernandez, Loretta A. (2020). Quantitative Method for Comparative Assessment of Particle Removal Efficiency of Fabric Masks as Alternatives to Standard Surgical Masks for PPE. Matter, 3(3),950-962. 10.1016/J.MATT.2020.07.006
  • Spronck, Bart, Ferruzzi, Jacopo, Bellini, Chiara, Caulk, Alexander W., Murtada, Sae-Il, Humphrey, Jay D. (2020). Aortic remodeling is modest and sex-independent in mice when hypertension is superimposed on aging. Journal of Hypertension, 38(7),1312-1321. 10.1097/HJH.0000000000002400
  • A. Korneva, L. Zilberberg, D.B. Rifkin, J.D. Humphrey, C. Bellini, Absence of LTBP-3 Attenuates the Aneurysmal Phenotype But Not Spinal Effects on the Aorta in Marfan Syndrome, Biomechanics and Modeling in Mechanobiology, 18(1), 2019,261-273
  • C. Bellini, N.J. Kristofik, M.R. Bersi, T.R. Kyriakides, J.D. Humphrey, A Hidden Structural Vulnerability in the Thrombospondin-2 Deficient Aorta Increases the Propensity to Intramural Delamination, Journal of the Mechanical Behavior of Biomedial Materials, 71, 2017, 397-406
  • C. Bellini, M.R. Bersi, A. Caulk, J. Ferruzzi, D.M. Milewicz, F. Ramirez, D.B. Rifkin, G. Tellides, H. Yanagiswa, J.D. Humphrey, Comparison of Ten Murine Models Reveals a Distinct Biomechanical Phenotype in Thoracuc Aortic Aneurysms, Journal of the Royal Society Interface, 14(130), 2017

Students

Feb 08, 2021

Spring 2021 PEAK Experience Recipients

Congratulations to the COE student recipients of the Spring 2021 PEAK Experiences Awards. The PEAK Experiences Awards are a progressively structured sequence of opportunities designed to support learners as they continue climbing to new heights of achievement in undergraduate research and creative endeavor throughout their Northeastern journeys. PEAK Experience Ascent Awardees Ryan Brady, COE’22, Chemical […]

Faculty

Apr 29, 2019

Faculty and Staff Awards 2019

Congratulations to all the winners of the faculty and staff awards, and to everyone for their hard work and dedication during the 2018-2019 academic school year. See Photo Gallery Faculty Fellow Matthew Eckelman, CEE Yongmin Liu, MIE Outstanding Teacher of First Year Engineering Students Joseph Depasquale, Chemistry Brian O’Connell, FYE Sumi Seo, Mathematics Matthew Webber, […]

Faculty

Sep 27, 2018

Oakes & Bellini Awarded $1.5M FEMA Grant to Study Health Effects of Wildland Fire Smoke to Firefighters

BioE Assistant Professors Jessica Oakes and Chiara Bellini were awarded a $1.5M award from the Assistance to Firefighters Grant Program (AFG), administered through The Department of Homeland Security (DHS) Federal Emergency Management Agency’s (FEMA) Grant Programs Directorate, for examining the “Health Consequences Following Acute and Chronic Firefighter Exposure to Wildland Fire Smoke.”

Faculty

Sep 26, 2018

Studying the Long-Term Health Hazards of E-Cigarettes

BioE Assistant Professors Jessica Oakes and Chiara Bellini are studying the health effects of vaping versus traditional combustible cigarettes.

Faculty

Mar 23, 2017

FY18 TIER 1 Award Recipients

21 COE faculty and affiliates were recipients of FY18 TIER 1 Interdisciplinary Research Seed Grants for 12 different projects representing $600K dollars of investment in research.

Sep 01, 2016

New Faculty Spotlight: Chiara Bellini

Chiara Bellini joins the Bioengineering department in Fall 2016 as an Assistant Professor.

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