Guohao Dai

Associate Professor,  Bioengineering


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  • 224 ISEC
  • 617.373.2207

Research Focus

3-D bioprinting technology, stem cells technology and vascular bioengineering


  • Post-doc, Vascular Biology, Harvard Medical School
  • Ph.D, Biomedical Engineering, Massachusetts Institute of Technology
  • M.S, Biomechanics, Peking University
  • B.S, Mechanical Engineering, Peking University

Honors & Awards

  • 2012 National Scientist Development Award, American Heart Association
  • 2014 NSF Career Award
  • 2015 Rising Star Award, Biomedical Engineering Society Cellular and Molecular Bioengineering
  • 2015 The Institute’s James M. Tien ’66 Faculty Early Career Award, Rensselaer Polytechnic Institute
  • 2018 College of Engineering Faculty Fellow
  • 2018 Fellow American Heart Association

Professional Affiliations

  • American Heart Association, Fellow
  • Biomedical Engineering Society
  • North American Vascular Biology Organization

Research Overview

3-D bioprinting technology, stem cells technology and vascular bioengineering

Selected Research Projects

  • Bioengineer Long-lasting 3D Neurovascular Microphysiological System to Model Chronic Inflammation-mediated Neurodegeneration
    • – Principal Investigator, NASA
  • CAREER: Engineer a Functional 3-D Vascular Niche to Support Neural Stem Cell Self-Renewal
    • – Principal Investigator, National Science Foundation
  • Differentiation Arterial and Venous Endothelial Cells from Embryonic Stem Cells
    • – Principal Investigator, National Institutes of Health
  • Elastic Printable Biomaterials for 3-D Bioprinting of Vascular Conduit
    • – Principal Investigator, National Institutes of Health
  • Transcriptional Regulation of Arterial Venous Differentiation
    • – Principal Investigator, American Heart Association

Selected Publications

  • Baltazar, Tânia, Merola, Jonathan, Catarino, Carolina, Xie, Catherine B., Kirkiles-Smith, Nancy C., Lee, Vivian, Hotta, Stephanie, Dai, Guohao, Xu, Xiaowei, Ferreira, Frederico C., Saltzman, W. Mark, Pober, Jordan S., Karande, Pankaj (2020). Three Dimensional Bioprinting of a Vascularized and Perfusable Skin Graft Using Human Keratinocytes, Fibroblasts, Pericytes, and Endothelial Cells. Tissue Engineering, 26(5-6),227-238. 10.1089/TEN.TEA.2019.0201
  • M.S. Ozturk, V.K. Lee, H. Zou, R.H. Friedel, X.Intes, G.Dai High Resolution Tomographic Analysis of in vitro 3D Glioblastoma Tumor Model under Long-Term Drug Treatment, Science Advances, 6(10), 2020, 7513
  • W. Song, A. Chiu, L.-H. Wang, R.E. Schwartz, B. Li, N. Bouklas, D.T. Bowers, V.K. Lee, G. Dai, M. Ma, et al. Engineering Transferrable Microvascular Meshes for Subcutaneous Islet Transplantation, Nature Communications, 10, 2019, 4602
  • L. Niklason, G. Dai, Arterial Venous Differentiation for Vascular Bioengineering, Annual Review of Biomedical Engineering, 2018, 4(20), 431-447
  • C. Xu, W. Lee, G. Dai, Y. Hong, Highly Elastic Biodegradable Single-Network Hydrogel for Cell Printing, ACS Applied Materials & Interfaces, 10(12), 2018, 9969-9979
  • T.B. Dorsey, D. Kim, A. Grath, D. James, G. Dai Multivalent Biomaterial Platform to Control the Distinct Arterial Venous Differentiation of Pluripotent Stem Cells, Biomaterials, 2018, 185, 1-12


May 18, 2022

Announcing Summer 2022 PEAK Experiences Awardees

Several engineering students and science students mentored by COE faculty are recipients of Northeastern’s Summer 2022 PEAK Experiences Awards.


Apr 21, 2022

DoD Discovery Award to Develop Human Vascular Malformation Model From iPSCs

BioE Associate Professor Guohao Dai received a $314K Discovery Award from the Department of Defense for “Human iPSCs derived 3D perfused model of vascular malformation”.

Guohao Dai, Abby Koppes, Ryan Koppes


Apr 04, 2022

$2M NASA Grant To Build Long Lasting Neurovascular Model

BioE Associate Professor Guohao Dai, ChE Associate Professor Abigail Koppes, and ChE Assistant Professor Ryan Koppes received a $2M grant from NASA titled “Bioengineer Long-lasting 3D Neurovascular Microphysiological System to Model Chronic Inflammation-mediated Neurodegeneration”.


Dec 23, 2021

COE Professors Selected in Stanford University List of Top 2% Scientists Worldwide

The following COE professors are among the top scientists worldwide selected by Stanford University representing the top 2 percent of the most-cited scientists with single-year impact in various disciplines. The selection is based on the top 100,000 by c-score (with and without self-citations) or a percentile rank of 2% or above. The list below includes […]

guohao dai, ryan koppes, & abigail koppes


May 20, 2021

Improving Vein Grafts for Patients with Cardiovascular Diseases

BioE Associate Professor Guohao Dai (PI), ChE Assistant Professors Ryan Koppes (PI), and Abigail Koppes (co-PI) were awarded a $430K NIH grant from the National Institute of Neurological Disorders and Stroke for “Bioengineer a Humanized Autonomic Neurovascular Innervation on a Chip”.

Glioblastoma stem cells


Apr 02, 2020

3D Printing Could Help in Finding Brain Cancer Treatments

BioE Associate Professor Guohao Dai, who specializes in 3D printing live tissue, created a three-dimensional model to study the development of brain tumors.

guohao dai, ryan koppes, & abigail koppes


Nov 12, 2019

AHA Grant to Explore the Innervation of Arterial Grafts

Associate Professor Guohao Dai from the Department of Bioengineering, Assistant Professor Ryan Koppes and Abigail Koppes from the Department of Chemical Engineering were awarded $200K from the American Heart Association (AHA) Innovative Project Award for “Bioengineer an autonomic neurovascular system to explore the innervation of arterial grafts”.


Nov 14, 2018

Dai Selected as AHA Fellow

BioE Associate Professor Guohao Dai was one of nine selected as a Fellow of the American Heart Association (FAHA) by the Council of Basic Cardiovascular Sciences of AHA.


May 01, 2018

Faculty and Staff Awards 2018

Congratulations to all the winners of the faculty and staff awards, and to everyone for their hard work and dedication during the 2017-2018 academic school year.


Nov 17, 2016

Exploring Vascular Disease with 3-D Bioprinter

BioE Associate Professor Guohao Dai has developed a 3-D bioprinter to create tissue cultures for use in disease modeling and drug discovery.

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