Srinivas Sridhar
Affiliated Faculty,
Bioengineering
Affiliated Faculty,
Chemical Engineering
University Distinguished Professor,
Physics
Contact
- s.sridhar@northeastern.edu
- 360 Huntington Avenue
Boston, Massachusetts 02115
Office
- 210 DA
- 617.373.2930
Research Focus
nanomedicine; neurotechnology; drug delivery, MRI imaging
About
Srinivas Sridhar, Ph.D. is University Distinguished Professor of Physics, Biomedical Engineering and Chemical Engineering at Northeastern University, and Lecturer on Radiation Oncology, Harvard Medical School. He previously served as Vice Provost for Research at Northeastern University, overseeing the University’s research portfolio.
An elected Fellow of the American Physical Society, Sridhar’s current areas of research are nanomedicine, neurotechnology and MRI imaging. His paper in Nature in 2003 was listed among Breakthroughs of 2003 by the journal Science. He has published more than 200 articles on nanomedicine, neurotechnology, nanophotonics, metamaterials, quantum chaos, superconductivity and collective excitations in materials.
As Founding Director of the Nanomedicine Innovation Center at Northeastern University, Sridhar established a Nanomedicine Center for synthesis and characterization of nanoparticle formulations. His team has prepared and characterized several nanoplatforms ranging from lipid, polymeric and metallic nanoparticles to implants for sustained release for drug delivery of chemotherapeutics and biologics such as PARP inhibitors and siRNA, for application in cancer, cardiovascular and neurological diseases. With his students he has developed a groundbreaking approach to quantitative MRI that is soon to be tested in patients. An entrepreneur, he has founded companies that are translating his discoveries to the clinic.
Sridhar is passionately committed to training future scientists and engineers and providing access to knowledge to all particularly to those from under-represented minority communities. He has trained more than 120 faculty, postdoctoral fellows, scientists, and graduate and undergraduate students. He is Director of the Nanomedicine Academy funded by grants for NSF and NIH, whose vision is to providing training in nanomedicine nationally and globally. He is Director of CaNCURE: Cancer Nanomedicine Coops for Undergraduate Research, an NIH R25 program to provide research training in cancer nanomedicine. He is Director and PI of the NSF IGERT Nanomedicine Science and Technology Center. He developed several first-of-their kind courses in Nanomedicine. These unique programs have taught hundreds of graduate and undergraduate students in several minority serving institutions, and led to institutional change in the form of new programs in nanomedicine. Sridhar’s contributions to education and training have been recognized by awards and invitations to speak and to participate in national panels on education.
For more information visit cancurecancer.org, www.northeastern.edu/igert, srinivassridhar.com.
Honors & Awards
- Biomedical Engineering Diversity Award 2016
- University Distinguished Professorship
Research Overview
nanomedicine; neurotechnology; drug delivery, MRI imaging
Selected Research Projects
- CaNCURE: Cancer Nanomedicine Co-ops for Undergraduate Research Experiences
- Principal Investigator, National Institutes of Health
- Nanoformulations and Sustained Delivery of PARP Inhibitors for Breast Cancer
- Principal Investigator, Department of Defense
- Nanomedicine Academy of Minority Serving Institutions
- Principal Investigator, National Science Foundation Development
- Nanoscale Magnetism of Novel Structures
- Principal Investigator, Air Force Research Laboratory
- Neuro-Optical Diagnostic System for Macular Degeneration
- Principal Investigator, National Institutes of Health
- Quantitative Non-Invasive Brain Imaging using Magnetic Nanoparticles
- Principal Investigator, National Institutes of Health
Department Research Areas
Selected Publications
- Zhang D., Singh B., Moerland J., Mitchell O., Lockwood L., Carapellucci S., Sridhar S., and Liby K.T. (2021). Sustained, Local Delivery of the PARP Inhibitor Talazoparib Prevents the Development of Mammary Gland Hyperplasia in Brca1-deficient Mice. Sci Rep, 11(1):1234. 10.1038/s41598-020-79663-7
- Yang S., Wallach M., Krishna A., Kurmasheva R., and Sridhar S. (2021). Recent Developments in Nanomedicine for Pediatric Cancer. J Clin Med, 10(7):1437. 10.3390/jcm10071437
- Rodell C.B., Baldwin P., Fernandez B., Weissleder R., Sridhar S., Dubach J.M. (2021). Quantification of Cellular Drug Biodistribution Addresses Challenges in Evaluating in vitro and in vivo Encapsulated Drug Delivery. Adv Ther (Weinh), 4(3):2000125. 10.1002/adtp.202000125
- Versek C., Banijamali S.M.A., Bex P., Lashkari K., Kamarthi S., and Sridhar S. (2021). Portable Diagnostic System for Age-Related Macular Degeneration Screening Using Visual Evoked Potentials. Eye Brain. 13:111-127. 10.2147/EB.S295745
- Timms L., Zhou T., Lyu Y., Qiao J., Mishra V., Lahoud R.M., Jayaraman G.V., Allegretti A.S., Drew D., Seethamraju R.T., Harisinghani M., and Sridhar S. (2021). Ferumoxytol-enhanced Ultrashort TE MRA and Quantitative Morphometry of the Human Kidney Vasculature. Abdom Radiol (NY). 10.1007/s00261-021-02984-2. Online ahead of print.
- Singh B., Yang S., Krishna A., and Sridhar S. (2020). Nanoparticle Formulations of Poly (ADP-ribose) Polymerase Inhibitors for Cancer Therapy. Front Chem.8:594619. 10.3389/fchem.2020.594619
- D. Zhang, P. Baldwin, A.S. Leal, S. Carapellucci, S. Sridhar, K.T. Liby, A Nano-Liposome Formulation of the Parp Inhibitor Talazoparib Enhances Treatment Efficacy and Modulates Immune Cell Populations in Mammary Tumors of BRCA- Deficient Mice, Theranostics, 9(21), 2019, 6224-6238
- J. Qiao, X. Cai, Q. Xiao, Z. Chen, P. Kulkarni, C. Ferris, S. Kamarthi, S. Sridhar, Data on MRI brain Lesion Segmentation using K-means and Gaussian Mixture Model-Expectation Maximization, Data Brief, 27, 2019, 104628
- P. Baldwin, A.W. Ohman, J.E. Medina, E.T. McCarthy, D.M. Dinulescu, S. Sridhar, Nanoformulation of Talazoparib Delays Tumor Progression and Ascites Formation in a Late Stage Cancer Model, Frontiers in Oncology, 9(353), 2019
Jan 31, 2025
2024 Stanford University Annual Assessment of Author Citations
The following COE professors are among the top scientists worldwide selected by Stanford University representing the top 2% of the most-cited scientists with single-year impact in various disciplines. The selection is based on the top 100,000 by c-score (with and without self-citations) or a percentile rank of 2% or above. The list below includes those who published a paper in 2024 or later.

Jul 24, 2024
PhD Spotlight: Shicheng Yang, PhD’24, Chemical Engineering
Shicheng Yang, PhD’24, chemical engineering, focused research on innovative drug delivery systems, including polymeric implants and lipid nanoparticles, for cancer treatment. He was named an inventor on “Processes for Nanoformulation of Molecular Inhibitors and Chemotherapeutics.”

May 22, 2024
Bioengineering PhD Develops and Commercializes Breakthrough MRI Technology
Codi Gharagouzloo, PhD’16, bioengineering, co-founded Imaginostics, commercializing a novel technology called QUTE-CE MRI, which is a platform technology for non-invasive imaging that transforms any MRI machine into a powerful quantitative diagnostic tool. Imaginostics was recognized as a finalist among more than 4,500 participants of Hello Tomorrow, a prestigious competition for deep tech startups.
May 08, 2024
2024 URF Scholars Recipients
Several engineering students received 2024 URF Scholars Awards from Northeastern’s Office of Undergraduate Research and Fellowships. URF Scholars are students who are graduating this year and who have earned a PEAK Experiences Award, applied for a distinguished fellowship, or participated in graduate school advising.

Feb 23, 2024
Exploring a Wealth of Options To Pursue Unique Educational Paths
Julia Treese, E’24, chemical engineering, started her Northeastern journey in the Explore program. After three co-ops and a variety of extracurriculars, she has found that biotech is her calling.
Dec 07, 2023
2023 Stanford University Annual Assessment of Author Citations
The following COE professors are among the top scientists worldwide selected by Stanford University representing the top 2% of the most-cited scientists with single-year impact in various disciplines. The selection is based on the top 100,000 by c-score (with and without self-citations) or a percentile rank of 2% or above.

Apr 19, 2022
Congratulations RISE: 2022 Winners
Congratulations to our engineering students who won awards at the RISE:2022 Research, Innovation and Scholarship Expo!
Oct 17, 2016
Professor Srinivas Sridhar Receives Three New Grants
Congratulations to COS Professor (BioE & ChE Affiliated Professor) Srinivas Sridhar who has recently received three new grants totaling $1.13M. 1. Quantitative Neurovascular Imaging for Drug Abuse Research (NIH/NIDA grant). […]
Jul 14, 2016
Professor Srinivas Sridhar Receives 2016 BMES Diversity Award
The Awards Committee of the Biomedical Engineering Society (BMES) Board of Directors has selected Professor Srinivas Sridhar from the College of Science and Chemical Engineering as the recipient of the […]
Mar 22, 2016
FY17 TIER 1 Award Recipients
23 COE faculty and affiliates were recipients of FY17 TIER 1 Interdisciplinary Research Seed Grants for 12 different projects representing over $600K dollars of investment in research.