Rouzbeh Amini

Associate Professor,  Mechanical and Industrial Engineering
Associate Professor,  Bioengineering

Contact

Office

  • 508 ISEC
  • 617.373.7688

Research Focus

Biomechanics, mechanobiology, biotransport

Education

  • PhD in Biomedical Engineering, University of Minnesota, Minneapolis, 2010

Honors & Awards

Professional Affiliations

  • International Society for Eye Research (ISER)
  • American Society for Engineering Education (ASEE)
  • American Heart Association (AHA)
  • Biomedical Engineering Society (BMES)
  • American Society of Mechanical Engineers (ASME)
  • Association for Research in Vision and Ophthalmology (ARVO)

Research Overview

Biomechanics, mechanobiology, biotransport

Laboratory for Soft Tissue Biomechanics

The Laboratory for Soft Tissue Biomechanics at Northeastern University conducts studies to understand how mechanical loading and structural properties at different scales (i.e. organ, tissue, extracellular matrix, and cellular/sub-cellular levels) affect the normal responses of soft tissues. We aim to determine how deviating from such native states may induce pathophysiological responses. Our group has been extending the scope of experimental techniques to quantify the mechanical and microstructural properties of soft tissues. We have also been developing multi-scale computational models of tissue biomechanics and mechanobiology based on the experimentally quantified responses at the cellular, extracellular matrix, and tissue levels.

Laboratory for Soft Tissue Biomechanics

Selected Research Projects

College Research Initiatives

Selected Publications

  • Nwotchouang, Blaise Simplice Talla, Eppelheimer, Maggie S., Pahlavian, Soroush Heidari, Barrow, Jack W., Barrow, Daniel L., Qiu, Deqiang, Allen, Philip A., Oshinski, John N., Amini, Rouzbeh, Loth, Francis (2021). Regional Brain Tissue Displacement and Strain is Elevated in Subjects with Chiari Malformation Type I Compared to Healthy Controls: A Study Using DENSE MRI. Annals of Biomedical Engineering, 10.1007/S10439-020-02695-7
  • Nwotchouang, Blaise Simplice Talla, Eppelheimer, Maggie S., Biswas, Dipankar, Pahlavian, Soroush Heidari, Zhong, Xiaodong, Oshinski, John N., Barrow, Daniel L., Amini, Rouzbeh, Loth, Francis (2021). Accuracy of cardiac‐induced brain motion measurement using displacement‐encoding with stimulated echoes (DENSE) magnetic resonance imaging (MRI): A phantom study. Magnetic Resonance in Medicine, 85(3),1237-1247. 10.1002/MRM.28490
  • Rashidi, Neda, Pant, Anup D., Salinas, Samuel D., Shah, Mickey, Thomas, Vineet S., Zhang, Ge, Dorairaj, Syril, Amini, Rouzbeh (2021). Iris stromal cell nuclei deform to more elongated shapes during pharmacologically-induced miosis and mydriasis. Experimental Eye Research, 202,108373. 10.1016/J.EXER.2020.108373
  • Amini, Rouzbeh, Cyrus Rezvanifar, S. (2020). Self-Efficacy Versus Gender: Project-Based Active Learning Techniques in Biomedical Engineering Introductory Computer Programming Courses. Journal of Biomechanical Engineering, 142(11). 10.1115/1.4047924
  • S.D. Salinas, M.M. Clark, R. Amini, The Effects of− 80° C Short-Term Storage on the Mechanical Response of Tricuspid Valve Leaflets, Journal of Biomechanics, 98, 2020, 109462
  • V.S. Thomas, V. Lai, R. Amini, A Computational Multi-Scale Approach to Investigate Mechanically-Induced Changes in Tricuspid Valve Anterior Leaflet Microstructure, Acta Biomaterialia, 94, 2019, 524-535
  • K. Amini Khoiy, K.T. Asgarian, F. Loth, R. Amini, Dilation of Tricuspid Valve Annulus Immediately After Rupture of Chordae Tendineae in Ex-Vivo Porcine Hearts, PLOS One, 13(11), 2018, e0206744
  • A.D. Pant, P. Gogte, V. Pathak-Ray, S.K. Dorairaj, R. Amini Increased Iris Stiffness in Patients with a History of Angle-Closure Glaucoma: An Image-Based Inverse Modeling Analysis, Investigative Ophthalmology & Visual Science, 59(10), 2018, 4134-4142
  • S.H. Pahlavian, J. Oshinski, X. Zhong, F. Loth, R. Amini Regional Quantification of Brain Tissue Strain Using Displacement-Encoding with Stimulated Echoes Magnetic Resonance Imaging, Journal of Biomechanical Engineering, 140(8), 2018
Rouzbeh Amini

Faculty

Jan 19, 2021

COE Alumnus, Now Professor Focuses in the Interdisciplinary Fields of Biomechanics and Mechanobiology

Rouzbeh Amini, associate professor of mechanical and industrial engineering, jointly appointed in bioengineering, first came to Northeastern in the early 2000s pursuing a master’s degree in mechanical engineering. He recalls his days as a graduate student at Northeastern fondly and didn’t imagine that he’d ever get the chance to come back to the university as […]

Rouzbeh Amini

Faculty

Nov 03, 2020

Understanding Biomechanical Changes in Heart Valves Following Pregnancy

MIE/BioE Associate Professor Rouzbeh Amini is researching “Multi-scale Assessment of Biomechanical Alterations in Tricuspid Valves Following Pregnancy” – a project awarded to him as an NSF CAREER Award in 2018.

Rouzbeh Amini

Faculty

Jan 03, 2020

New Faculty Spotlight: Rouzbeh Amini

Rouzbeh Amini joins the Mechanical Engineering department in January 2020 as an Associate Professor with a joint appointment in Bioengineering.

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