Charles DiMarzio
Associate Professor, Electrical and Computer Engineering
Affiliated Faculty, Mechanical and Industrial Engineering
Affiliated Faculty, Bioengineering
Office
- 302 Stearns
- 617.373.2034
Related Links
Research Focus
Optics, microscopy, coherent detection, interaction of light and sound waves, hyperspectral imaging, diffusive optical tomography multi-model imaging and remote sensing. Activities include computer modeling, designing, building, and testing of hardware, and processing the resulting data
About
Prof. DiMarzio holds a BS in Engineering Physics (University of
Maine), MS in Physics (WPI), and Ph.D. in Electrical and Computer
Engineering (Northeastern University). Prior to coming to
Northeastern, he was an engineer at Raytheon Company, working in
coherent CO2 laser radar for remote sensing of the atmosphere and for
other applications. At Northeastern, he continued his interest in
remote sensing but moved toward applications in medicine and
biology. He invented optical quadrature microscopy for imaging phase
objects, which has been used in research on embryo development. He
also led the development of the Keck 3-D fusion microscope which
combines optical quadrature with confocal and multi-photon microscopy
for many applications in medicine and biology. He also pioneered novel
techniques for medical imaging with ultrasound-modulated light. He
has developed novel imaging approaches for measurements of collagen
fibrils and monomers.
He teaches graduate courses in optics, and a variety of undergraduate
courses including engineering design, electronics, and subsurface
sensing & imaging. Prof. DiMarzio’s Optical Science Laboratory enjoys
collaborations with the Gordon Center for Subsurface Sensing and
Imaging Systems, ALERT, Prof. Jeffrey Ruberti’s laboratory at
Northeastern, the dermatology department at Memorial Sloan
Kettering Cancer Center, and Universidad de los Andes in Chile.
Education
- PhD, Northeastern University, 1996
Honors & Awards
- 2022 SPIE Fellow
- 2021 Senior Member of SPIE the International Society of Optics and Photonics
- Senior Member of Optica (formerly OSA)
Research Overview
Optics, microscopy, coherent detection, interaction of light and sound waves, hyperspectral imaging, diffusive optical tomography multi-model imaging and remote sensing. Activities include computer modeling, designing, building, and testing of hardware, and processing the resulting data
Selected Research Projects
- Coded-Illumination Fourier Ptychography for High-Content MultiModal Imaging
- – Principal Investigator, National Science Foundation
- Collagen Monomer Imaging
- – Co-Principal Investigator, National Institutes of Health
- Light Scattering Research
- – Principal Investigator, Draper Labs
Research Centers and Institutes
Department Research Areas
Selected Publications
- Alzola, Rodrigo P., Siadat, Seyed Mohammad., Gajjar, Anuj., Stureborg, Rickard., Ruberti, Jeffrey W., Delpiano, Jose., and DiMarzio, Charles A. (2021). Method for Measurement of Collagen Monomer Orientation in Fluorescence Microscopy. Journal of Biomedical Optics, 26(7):076501
- Siadat, Seyed Mohammad., Silverman, Alexandra A., DiMarzio, Charles A., and Ruberti, Jeffrey W. (2021). Measuring Collagen Fibril Diameter with Differential Interference Contrast Microscopy. Journal of Structural Biology, 107697
- Loupe, Neili., Doan, Jonathan., Cruse, Ryan., DiMarzio, Charles A., and Smotkin, Eugene S. (2018). Laser focal Point Sequestration for Raman Micro-Spectroscopy of Thermally Sensitive Fuel Cell Catalytic Layers. Electrochimica Acta
- A.E. Draghici, D. Potart, J.L. Hollmann, V. Pera, Q. Fang, C.A. DiMarzio J.A. Taylor, M.J. Niedre, S.J. Shefelbine, Near Infrared Spectroscopy for Measuring Changes in Bone Hemoglobin Content after Exercise in Individuals with Spinal Cord Injury, Journal of Orthopaedic Research, 2017
- Z.R. Hoffman, C.A. DiMarzio, Single-Image Structured Illumination Using Hilbert Transform Demodulation, Journal of Biomedical Optics, 22(5), 2017, 056011–056011
- Z. R. Hoffman and C. A. DiMarzio, Super-Resolution Structured Illumination in Optically Thick Specimens Without Fluorescent Tagging, Journal of Biomedical Optics, 22(11), 2017, 1–11
- A. Vakili, J.L. Hollmann, R.G. Holt, C.A. DiMarzio, Enhanced Tagging of Light Utilizing Acoustic Radiation Force with Speckle Pattern Analysis, Journal of Biomedical Optics, 22(10), 2017, 106004
- J.L. Hollmann, R. Horstmeyer, C. Yang, C.A DiMarzio, Diffusion Model for Ultrasound-Modulated Light, Journal of Biomedical Optics, 19(3), 2014, 035005
Jan 03, 2024
Northeastern Students Develop Robotic Boat To Attack Invasive Plants
A capstone project supervised by ECE Associate Professor Charles DiMarzio and MIE Associate Professor Randall Erb that developed an autonomous robotic boat to map the invasive hydrilla plant has been featured in The Robot Report, Hartford Courant, BNN Breaking, and Government Technology.
Dec 15, 2023
Capstone Students Design Robotic Boat to Combat Invasive Plant
Engineering capstone students built an autonomous robotic boat equipped with a hyperspectral camera to map the invasive hydrilla plant and help scientists control its spread in Connecticut waters. The project is a collaboration between the electrical engineering department, the mechanical engineering department, the Robotics and Intelligent Vehicles Research Lab, and the Connecticut Agricultural Experiment Station.
Jan 18, 2022
DiMarzio Selected as Fellow of SPIE
ECE Associate Professor Charles DiMarzio was selected by the International Society for Optics and Photonics (SPIE) as a Fellow for his significant scientific and technical contributions in the multidisciplinary fields of optics, photonics, and imaging.
Sep 17, 2021
A Dialogue of Civilizations Led to Friendship and Joint Research
After a Dialogue of Civilizations course with ECE Associate Professor Charles DiMarzio, a group of students teamed up to research a better method of visualizing collagen monomer orientations, and their research has been published in The Journal of Biomedical Optics.
Jul 26, 2021
DiMarzio Selected as SPIE Senior Member
ECE Associate Professor Charles DiMarzio was selected by the International Society for Optics and Photonics (SPIE) as a 2021 Senior Member.
Jun 01, 2020
Patent for Single Image Optical Sectioning
ECE Associate Professor Charles DiMarzio awarded a patent for “Methods, systems, and devices for optical sectioning”.
Aug 07, 2018
Professor DiMarzio's group Work on Development of All-weather Lidar
ECE Associate Professor Charles DiMarzio’s group is collaborating with colleagues at Draper Laboratories on the development of an all-weather Lidar.
Apr 28, 2016
DiMarzio Awarded Patent
ECE Associate Professor Charles DiMarzio awarded a patent for “Deep tissue focal fluorescence imaging with digitally time-reversed ultrasound-encoded light”.
Jan 25, 2016
I.Q. Project Highlight: Medical Imaging
Despite the rapid progress in biomedical optics in the past decade, a need for ever-greater speed, resolution, and depth of imaging persists. For example, tissue sectioning with confocal reflectance microscopy to evaluate cellular and sub-cellular features in vivo is a popular method but has limitations. This technique can produce 2D images with 500 x 500 […]
May 26, 2015
DiMarzio Awarded $300K NSF Grant
ECE Associate Professor Charles DiMarzio was awarded a $300K NSF grant for "Coded-illumination Fourier Ptychography for High-content Multimodal Imaging".