Charles DiMarzio

Associate Professor,  Electrical and Computer Engineering
Affiliated Faculty,  Mechanical and Industrial Engineering
Affiliated Faculty,  Bioengineering

Contact

Social Media

Office

  • 302 Stearns
  • 617.373.2034

Research Focus

Optics, microscopy, coherent detection, interaction of light and sound waves, hyperspectral imaging, diffusive optical tomography multi-model imaging and remote sensing. Activities include computer modeling, designing, building, and testing of hardware, and processing the resulting data

About

Prof. DiMarzio holds a BS in Engineering Physics (University of
Maine), MS in Physics (WPI), and Ph.D. in Electrical and Computer
Engineering (Northeastern University). Prior to coming to
Northeastern, he was an engineer at Raytheon Company, working in
coherent CO2 laser radar for remote sensing of the atmosphere and for
other applications. At Northeastern, he continued his interest in
remote sensing but moved toward applications in medicine and
biology. He invented optical quadrature microscopy for imaging phase
objects, which has been used in research on embryo development. He
also led the development of the Keck 3-D fusion microscope which
combines optical quadrature with confocal and multi-photon microscopy
for many applications in medicine and biology. He also pioneered novel
techniques for medical imaging with ultrasound-modulated light.  He
has developed novel imaging approaches for measurements of collagen
fibrils and monomers.

He teaches graduate courses in optics, and a variety of undergraduate
courses including engineering design, electronics, and subsurface
sensing & imaging. Prof. DiMarzio’s Optical Science Laboratory enjoys
collaborations with the Gordon Center for Subsurface Sensing and
Imaging Systems, ALERT,  Prof. Jeffrey Ruberti’s laboratory at
Northeastern, the dermatology department at Memorial Sloan
Kettering Cancer Center, and Universidad de los Andes in Chile.

Education

  • PhD, Northeastern University, 1996

Honors & Awards

  • 2021 Senior Member of SPIE the International Society of Optics and Photonics

Research Overview

Optics, microscopy, coherent detection, interaction of light and sound waves, hyperspectral imaging, diffusive optical tomography multi-model imaging and remote sensing. Activities include computer modeling, designing, building, and testing of hardware, and processing the resulting data

Optical Science Lab

OSL’s goals are to provide a facility for advanced research in these areas in order to address the needs of our research sponsors, and to train the next generation of researchers for industry, academia, and the government.

Optical Science Laboratory

Selected Research Projects

Department Research Areas

Selected Publications

  • Alzola, Rodrigo P., Siadat, Seyed Mohammad., Gajjar, Anuj., Stureborg, Rickard., Ruberti, Jeffrey W., Delpiano, Jose., and DiMarzio, Charles A. (2021). Method for Measurement of Collagen Monomer Orientation in Fluorescence Microscopy. Journal of Biomedical Optics, 26(7):076501
  • Siadat, Seyed Mohammad., Silverman, Alexandra A., DiMarzio, Charles A., and Ruberti, Jeffrey W. (2021). Measuring Collagen Fibril Diameter with Differential Interference Contrast Microscopy. Journal of Structural Biology, 107697
  • Loupe, Neili., Doan, Jonathan., Cruse, Ryan., DiMarzio, Charles A., and Smotkin, Eugene S. (2018). Laser focal Point Sequestration for Raman Micro-Spectroscopy of Thermally Sensitive Fuel Cell Catalytic Layers. Electrochimica Acta
  • A.E. Draghici, D. Potart, J.L. Hollmann, V. Pera, Q. Fang, C.A. DiMarzio J.A. Taylor, M.J. Niedre, S.J. Shefelbine, Near Infrared Spectroscopy for Measuring Changes in Bone Hemoglobin Content after Exercise in Individuals with Spinal Cord Injury, Journal of Orthopaedic Research, 2017
  • Z.R. Hoffman, C.A. DiMarzio, Single-Image Structured Illumination Using Hilbert Transform Demodulation, Journal of Biomedical Optics, 22(5), 2017, 056011–056011
  • Z. R. Hoffman and C. A. DiMarzio, Super-Resolution Structured Illumination in Optically Thick Specimens Without Fluorescent Tagging, Journal of Biomedical Optics, 22(11), 2017, 1–11
  • A. Vakili, J.L. Hollmann, R.G. Holt, C.A. DiMarzio, Enhanced Tagging of Light Utilizing Acoustic Radiation Force with Speckle Pattern Analysis, Journal of Biomedical Optics, 22(10), 2017, 106004
  • J.L. Hollmann, R. Horstmeyer, C. Yang, C.A DiMarzio, Diffusion Model for Ultrasound-Modulated Light, Journal of Biomedical Optics, 19(3), 2014, 035005

Faculty

Sep 17, 2021

A Dialogue of Civilizations Led to Friendship and Joint Research

After a Dialogue of Civilizations course with ECE Associate Professor Charles DiMarzio, a group of students teamed up to research a better method of visualizing collagen monomer orientations. This idea traveled from the Andes to the Green Mountains. Three years later, it’s finally published. Main photo by Matthew Modoono/Northeastern University In 1921, Benton MacKaye climbed […]

Charles DiMarzio

Faculty

Jul 26, 2021

DiMarzio Selected as SPIE Senior Member

ECE Associate Professor Charles DiMarzio was selected by the International Society for Optics and Photonics (SPIE) as a 2021 Senior Member.

Charles DiMarzio

Faculty

Jun 01, 2020

Patent for Single Image Optical Sectioning

ECE Associate Professor Charles DiMarzio awarded a patent for “Methods, systems, and devices for optical sectioning”.

Faculty

Aug 07, 2018

Professor DiMarzio's group Work on Development of All-weather Lidar

ECE Associate Professor Charles DiMarzio’s group is collaborating with colleagues at Draper Laboratories on the development of an all-weather Lidar.

Apr 28, 2016

DiMarzio Awarded Patent

ECE Associate Professor Charles DiMarzio awarded a patent for “Deep tissue focal fluorescence imaging with digitally time-reversed ultrasound-encoded light”.

Jan 25, 2016

I.Q. Project Highlight: Medical Imaging

Despite the rapid progress in biomedical optics in the past decade, a need for ever-greater speed, resolution, and depth of imaging persists. For example, tissue sectioning with confocal reflectance microscopy to evaluate cellular and sub-cellular features in vivo is a popular method but has limitations. This technique can produce 2D images with 500 x 500 […]

May 26, 2015

DiMarzio Awarded $300K NSF Grant

ECE Associate Professor Charles DiMarzio was awarded a $300K NSF grant for "Coded-illumination Fourier Ptychography for High-content Multimodal Imaging".

Aug 27, 2014

Infrared Imaging System

ECE Associate Professor Charles DiMarzio was awarded a patent for his “Tunable laser-based infrared imaging system and method of use thereof ”. 

May 09, 2014

DiMarzio Professor of the Year

ECE Associate Professor Charles DiMarzio was selected Professor of the Year by Eta Kappa Nu for his outstanding contributions to the ECE department.

Mar 20, 2014

Congratulations to recipients of the FY15 TIER 1 Interdisciplinary Research Seed Grants

19 COE faculty were recipients of FY15 TIER 1 Interdisciplinary Research Seed Grants for 11 different projects representing over $500K dollars of investment in research.

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