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EXPLORE NORTHEASTERN

Jeffrey W. Ruberti

Professor,  Bioengineering

Contact

Office

  • 617.373.3984

Research Focus

tissue engineering of load-bearing matrix (bone, cornea); bioreactor design; multi-scale mechanobiochemistry; statistical mechanics; energetics microscopy; high-resolution imaging; biopolymer self-assembly

Education

  • PhD (1998), Biomedical Engineering, Tulane University

Honors & Awards

  • Soren Buus Outstanding Research Award (2008), College of Engineering, Northeastern University
  • Dean’s Service Award (2011), College of Engineering, Northeastern University

Teaching Interests

  • Capstone Design
  • Biomechanics
  • Principles of Bioengineering

Professional Affiliations

  • American Association for the Advancement of Science
  • American Society of Mechanical Engineers International
  • Biomedical Engineering Society

Research Focus

tissue engineering of load-bearing matrix (bone, cornea); bioreactor design; multi-scale mechanobiochemistry; statistical mechanics; energetics microscopy; high-resolution imaging; biopolymer self-assembly

Research Initiatives

BioMachine Integration
Integrated Modeling, Inference, and Computing

Department Research Areas

Biomechanics, Biotransport and MechanoBiology
Molecular, Cell, and Tissue Engineering

Selected Publications

  • J.A. Paten, S. Siadat, M.E. Susilo, I.N. Ebraheim, J.L. Stoner, J.P. Rothstein, J.W. Ruberti, Flow-Induced Crystallization of Collagen: A Potentially Critical Mechanism in Early Tissue Formation, ACS Nano, 10(5), 2016, 5027-5040
  • B. Wingender, P. Bradley, N. Saxena, J.W. Ruberti, L. Gower, Biomimetic Organization of Collagen Matrices to Template Bone-Like Microstructures, Matrix Biology, 52-54, 2016, 384-396
  • M. Susilo, J. Paten, E. Sander, T.D. Nguyen, J.W. Ruberti, Collagen Network Strengthening Following Cyclic Tensile Loading, Interface Focus, 6(1), 2016
  • T.K. Tonge, J.W. Ruberti, T.D. Nguyen, A Micromechanical Modeling Study of the Mechanical Stabilization of Enzymatic Degradation of Collagen Tissues, Biophysical Journal, 109(12), 2015, 2689-2700
  • E.H. Zhou, C. Watson, R. Pizzo, J. Cohen, Q. Dang, P.M. DeBarros, C.Y. Park, C. Chen, J.D. Brain, J.P. Butler, J.W. Ruberti, J.J. Fredberg, P. Demokritou, Assessing the Impact of Engineered Nanoparticles on Wound Healing Using a Novel in Vitro Bioassay, Nanomedicine, 9(18), 2014, 2803-2815
  • D. Karamichos C.B. Rich, R. Zareian, A.E.K. Hutcheon, J.W. Ruberti, V. Trinkaus-Randall, J.D. Zieske, TGF-ß3 Stimulates Stromal Matrix Assembly by Human Corneal Keratocyte-like Cells, Investigative Ophthalmology and Visual Science, 54(10), 2013, 6612-6619

Faculty

Aug 06, 2019

Using Collagen to Help Repair Tendons

BioE Professor Jeff Ruberti is developing a method to use collagen to help speed up the recovery after a tendon is injured.

Faculty

Feb 26, 2019

Ruberti Awarded Patent

BioE Professor Jeffrey Ruberti was awarded a patent for creating a “Mechanochemical collagen assembly.”

Faculty

Dec 18, 2018

Five COE Projects Selected for GapFund360

Congratulations to ECE Associate Professors Kaushik Chowdhury, Raymond Fu, Matteo Rinaldi, ECE Professor Vincent Harris, and BioE Professor Jeff Ruberti whose projects were selected for Phase 1 2018 funding by Northeastern’s GapFund360 program.

Faculty

Aug 21, 2018

$1M NSF Grant to Advance the Study of Single-Molecule Research

BioE Professor Jeffrey Ruberti (co-PI) along with bioengineering affiliated and College of Science faculty, including Professor Mark Williams (PI), and Associate Professors Penny Beuning (co-PI), Meni Wanunu (co-PI), and Ke Zhang (co-PI) were awarded a $1M NSF grant for the “Acquisition of a Lumick’s SuperC-TRAP correlative optical tweezers and fluorescence microscope (CTFM) system.”

Faculty

Dec 19, 2016

Ruberti Awarded Patent for Collagen Fibrillar Construction

BioE Professor Jeff Ruberti was awarded a patent for “Collagen fibrillar construction” that can be used for tissue engineering.

Jun 20, 2016

Frozen Sample Extraction

Bioengineering Professor Jeffrey Ruberti was awarded a patent for “Systems, methods, & devices for frozen sample distribution”.

Nov 17, 2015

Organizing Microparticles

BioE Professor Jeffrey Ruberti was awarded a patent for "Microparticle organization".

Sep 18, 2015

Interdisciplinary Approach to Treat Vascular Diseases

ChE Assistant Professor Eno Ebong is using interdisciplinary research to search for the cause and treat­ment of vas­cular dis­eases that cause heart attacks and strokes.

Jul 07, 2015

Ruberti Gets Prestigious Honor

BioE Professor Jeff Ruberti was selected to be a member of NIH’s Bioengineering of Neuroscience, Vision and Low Vision Technologies Study Section at the Center for Scientific Review.

May 27, 2015

Collagen Fibrillar Construction

MIE Professor Jeff Ruberti was awarded a patent for developing methods and compositions for organizing collagen into fibrillar networks.

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