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Sandra Shefelbine

Professor,  Mechanical and Industrial Engineering
Professor,  Bioengineering

Contact

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Office

  • 617.373.3199

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Research Focus

Multi-scale bone biomechanics–how the structure and composition of bone influences its mechanical properties; mechano-adaptation of bone and joint– how tissue responds to mechanical signals

Education

  • PhD (2002), Mechanical Engineering, Stanford University

Honors & Awards

  • 2011 Imperial College London Rector’s Medal of Excellence in Teaching
  • 2010 Royal Academy of Engineering Exxon Mobil Teaching Award
  • 2010 Faculty of Engineering Outstanding Teaching Award
  • 2010 Department of Bioengineering student selected ‘Best Teacher’ Award
  • 2005 RCUK Academic Fellowship
  • 2002 National Science Foundation International Research Fellowship

Teaching Interests

  • Solid mechanics
  • Dynamics
  • Musculoskeletal biomechanics

Research Focus

Multi-scale bone biomechanics–how the structure and composition of bone influences its mechanical properties; mechano-adaptation of bone and joint– how tissue responds to mechanical signals

Selected Publications

  • R.B. Woodward, S.J. Shefelbine, R. Vaidyanathan, Pervasive Monitoring of Motion and Muscle Activation: Inertial and Mechanomyography Fusion, IEEE/ASME Transactions on Mechatronics, 22(5), 2017, 2022-2033
  • R. DeSouza, B. Javaheri, R.S. Collinson, C. Chenu, S.J. Shefelbine, P.D. Lee, A.A. Pitsillides, Prolonging Disuse in Aged Mice Amplifies Cortical but not Trabecular Bones’ Response to Mechanical Loading, Journal of Musculoskeletal & Neuronal Interactions, 17(3), 2017, 218-225
  • K.P. Chadwick, S.J. Shefelbine, Pitsillides, J.R. Hutchinson, Finite-Element Modelling of Mechanobiological Factors Influencing Sesamoid Tissue Morphology in the Patellar Tendon of an Ostrich, Royal Society Open Science, 4(6), 2017, 170133
  • P. Yadav, S.J. Shefelbine, E. Pontén, E.M. Gutierrez-Farewik, Influence of Muscle Groups’ Activation on Proximal Femoral Growth Tendency, Biomechanics and Modeling in Mechanobiology, 2017
  • A.E. Draghici, D. Potart, J.L. Hollmann,V. Pera, Q. Fang, C.A. DiMarzio, J.A.Taylor, M.J. Niedre, S.J. Shefelbine, Near Infrared Spectroscopy for Measuring Changes in Bone Hemoglobin Content after Exercise in Individuals with Spinal Cord Injury, Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society, 36(1), 2017, 183-191
  • A.E. Draghici, G. Picard, J.A. Taylor S.J. Shefelbine, Assessing Kinematics and Kinetics of Functional Electrical Stimulation Rowing, Journal of Biomechanics, 53, 2017, 120-126
  • M. Nguyen, P. Singhal, J.W. Piet, S.J. Shefelbine, M. Maden, S.R. Voss, J. R. Monaghan, Retinoic Acid Receptor Regulation of Epimorphic and Homeostatic Regeneration in the Axolotl, Development (Cambridge, England), 144(4), 2017, 601-611

Alumni

Nov 15, 2018

Dream Co-op to Full Time Job

“I’m using my undergrad experience and my graduate experience that I built upon for my professional experience,” said Vineel Kondiboyina, MS, Bioengineering 2018. For many students, it is a dream to co-op with a company, end up loving the experience, and later ending up working for that company full time. For Vineel Kondiboyina, that is […]

Faculty

Jul 27, 2017

Shefelbine Awarded $650K NSF Grant

MIE/BioE Associate Professor Sandra Shefelbine awarded $650K NSF "Mechanobiology of Joint Morphogenesis: Manipulating Salamander Limbs" grant to study joint development by examining the regenerating limbs of salamanders.

Faculty

Feb 01, 2017

Ambika Bajpayee receives Department of Defense Discovery Award

BioE Assistant Professor Ambika Bajpayee (PI) and MIE/BioE Associate Professor Sandra Shefelbine (Collaborator) awarded a $310K DOD Peer Reviewed Medical Research Program Discovery Award

Aug 16, 2016

Different Loads on Bones Can Cause them to Break

Using the injury of French gymnast Samir Ait Said during the Olympics, MIE associate professor Sandra Shefelbine explains how bones can break when different loads are placed on them.

Undergraduate

Sep 24, 2015

Research Fair a Big Success

The COE Undergraduate Research Lab fair gathered hundreds of students eager to learn about the research opportunities available to them.

Aug 10, 2015

Understanding Toughness

MIE Associate Professor Sandra Shefelbine, Assistant Professor Randal Erb & Physics Professor Alain Karma received a $445K NSF grant to determine the toughness of a material and try to recreate it with synthetic components.

Undergraduate

May 20, 2015

Paraplegia Power Row

MIE capstone students have designed a rowing machine which would allow those with paraplegia to exercise without the need for a trainer

Jul 15, 2014

Examining Properties of Bones

MIE Associate Professor Sandra Shefelbine & Assistant Professor Marilyn Minus were awarded a $384K NSF grant to study the properties that make up a bone's strength and toughness.

Jun 21, 2013

Body of work

Sandra She­fel­bine has always been inter­ested in the human body as a mechan­ical system: “The lungs are gas exchangers and the heart is a pump,” said the asso­ciate pro­fessor of engi­neering. As an under­grad­uate simul­ta­ne­ously studying heat transfer and evo­lu­tionary biology, she real­ized that the system of par­allel arteries and veins in arctic birds’ legs, which […]

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