Related News for Nikolai Slavov

Northeastern Among Top 100 Universities for Utility Patents

Northeastern University, recognized for its excellence in innovation and entrepreneurship, has once again been named one of the top 100 universities worldwide for securing utility patents by the National Academy of Inventors.

Addressing Risk Factors and Potential Treatments of Alzheimer’s and Dementia

BioE Associate Professor Nikolai Slavov and Bouve Associate Professor Becky Briesacher provide insight into the differences between Alzheimer’s and dementia.

2023 Stanford University Annual Assessment of Author Citations

The following COE professors are among the top scientists worldwide selected by Stanford University representing the top 2% of the most-cited scientists with single-year impact in various disciplines. The selection is based on the top 100,000 by c-score (with and without self-citations) or a percentile rank of 2% or above. The list below includes those […]

Slowing the Progression of Alzheimer’s Disease

BioE Associate Professor Nikolai Slavov is investigating methods to slow the progression of Alzheimer’s, which is a specific form of dementia.

PhD Spotlight: Jason Derks, PhD’22, Bioengineering

Jason Derks’ PhD’22, bioengineering, research focused on developing new methods for high throughput proteomics and using them for quantifying the proteomes of single nuclei from macrophage cells responding to bacterial antigens. He developed technology he would call “plexDIA,” which he published in Nature Biotechnology in 2022.

Nikolai Slavov

New Methods of Analyzing Single Cell Proteomics

Allen Distinguished Investigator and BioE Associate Professor Nikolai Slavov was awarded a patent for “Mass spectrometry technique for single cell proteomics.”

Professor’s ‘Game-changing’ Alzheimer’s Research a Major Beneficiary of $50 Million Grant

A new research institute led by Allen Distinguished Investigator and BioE Associate Professor Nikolai Slavov is the principal beneficiary of a $50 million grant from two investors, Schmidt Futures and Citadel, to develop new techniques for studying Alzheimer’s disease.

Nikolai Slavov

Extending the Sensitivity, Consistency and Depth of Single-Cell Proteomics

The laboratory of Allen Distinguished Investigator and BioE Associate Professor Nikolai Slavov published their research on “Prioritized mass spectrometry increases the depth, sensitivity and data completeness of single-cell proteomics” in Nature Methods. Their method consistently analyzes thousands of prioritized peptides across all single cells (thus increasing data completeness) while maximizing instrument time spent analyzing identifiable peptides, thus increasing proteome depth.

Nikolai Slavov

Schmidt Futures Gives $50M for Life Science Research Including Single-Cell Proteomics Institute

The GenomeWeb article “Schmidt Futures Gives $50M for Life Science Research Including Single-Cell Proteomics Institute” highlights the Parallel Squared Technology Institute (PTI), a new non-profit research institute recently launched by Allen Distinguished Investigator and BioE Associate Professor Nikolai Slavov and former bioengineering students Aleksandra Petelski, PhD’22, and Harrison Specht, PhD’22.

Nikolai Slavov

PTI Launches to Scale Protein Analysis Towards Scientific and Medical Breakthroughs

Allen Distinguished Investigator and BioE Associate Professor Nikolai Slavov launched his new Parallel Squared Technology Institute (PTI) to catalyze a leap in biomedical research by enabling protein analysis with single-cell resolution at unprecedented throughput.

Nikolai Slavov

Workflows for Single-Cell Proteomics

Allen Distinguished Investigator and BioE Associate Professor Nikolai Slavov’s research on “Initial recommendations for performing, benchmarking and reporting single-cell proteomics experiments” was published in Nature Methods.

Nikolai Slavov

Single-Cell Proteomics Bypasses Bottlenecks, Sways Skeptics

Research from the laboratory of Allen Distinguished Investigator and BioE Associate Professor Nikolai Slavov on nPOP (published in Genome Biology) and plexDIA (published in Nature) was featured in the Genetic Engineering & Biotechnology article “Single-Cell Proteomics Bypasses Bottlenecks, Sways Skeptics”.

Single Cell Protein Analysis for Precision Medicine

Inside Precision Medicine published an article entitled “Untangling the Complexities of Single Cell Protein Analysis” that highlights the latest research from the team of Allen Distinguished Investigator and BioE Associate Professor Nikolai Slavov. The research was conducted in the Slavov Laboratory by doctoral students Andrew Leduc, Jason Derks and colleagues.

Uncovering Proteomic Patterns One Cell at a Time

Research from the laboratory of Allen Distinguished Investigator and BioE Associate Professor Nikolai Slavov on Uncovering Proteomic Patterns One Cell at a Time was featured in Genetic Engineering & Biotechnology News.

2022 Stanford University Annual Assessment of Author Citations

The following COE professors are among the top scientists worldwide selected by Stanford University representing the top 2 percent of the most-cited scientists with single-year impact in various disciplines. The selection is based on the top 100,000 by c-score (with and without self-citations) or a percentile rank of 2% or above. The list below includes […]

Sensitive Protein Analysis with plexDIA

Technology for sensitive protein analysis developed in the laboratory of BioE Associate Professor and Allen Distinguished Investigator Nikolai Slavov was highlighted in a Nature Methods article Sensitive protein analysis with plexDIA.

Nature Biotechnology Published a Framework for Multiplicative Scaling of Single-Cell Proteomics Developed in the Slavov Laboratory

The laboratory of Allen Distinguished Investigator and BioE Associate Professor Nikolai Slavov published “Increasing the throughput of sensitive proteomics by plexDIA” in Nature Biotechnology.

Faculty and Staff Awards 2022

Congratulations to all the winners of the faculty and staff awards, and to everyone for their hard work and dedication during the 2021-2022 academic school year.

COE Professors Selected in Stanford University List of Top 2% Scientists Worldwide

The following COE professors are among the top scientists worldwide selected by Stanford University representing the top 2 percent of the most-cited scientists with single-year impact in various disciplines. The selection is based on the top 100,000 by c-score (with and without self-citations) or a percentile rank of 2% or above. The list below includes […]

Research from the Slavov Laboratory published in Nature Protocols

Research from the laboratory of BioE Associate Professor and Allen Distinguished Investigator Nikolai Slavov has been published as “Multiplexed single-cell proteomics using SCoPE2” in Nature Protocols.  

Slavov Research Featured on Cover of C&EN

BioE Associate Professor and Allen Distinguished Investigator Nikolai Slavov’s research on “Individual cells’ proteins vary. Single-cell proteomics can now show how” was featured on the cover of the C&EN journal. In Brief Measurements of cell mixtures can hide differences between cells that might be important in biology or disease studies. Researchers have long had tools […]

Nikolai Slavov

Identifying Novel Markers of Senescence Cells

BioE Associate Professor Nikolai Slavov, in collaboration with Massachusetts General Hospital, was awarded a $588K NIH grant from the National Cancer Institute for “Single-Cell Proteomic Identification of Novel Markers of Senescence.”

Illustration of the two paths to the proteome.

Single-cell Proteomics takes Centre Stage

BioE Associate Professor and Allen Distinguished Investigator Nikolai Slavov was featured in the Nature technology feature “Single-cell proteomics takes centre stage” which highlights single-cell proteomics technology developed by the Slavov Laboratory.

Towards resolving proteomes in single cells

BioE Associate Professor Nikolai Slavovo was featured in the Nature Methods article “Towards resolving proteomes in single cells” which highlights single-cell proteomics methods (SCoPE-MS and SCoPE2) developed by the Slavov Laboratory, and their application to characterising the emergence of molecular diversity in a type of innate immune cells, macrophages.

abstract photo of women doctor pointing to tablet with medical imagery around it

Just What the Doctor Ordered

Human beings are some of the most complex systems in the world, and responses to illness, disease, and impairments manifest in countless different ways. When it comes to making sure that your system stays up and running, healthcare professionals typically have their own deep well of knowledge—but the addition of artificial intelligence tools offers unprecedented […]

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Nature Biotechnology Perspective on Increasing proteomics throughput

BioE Assistant Professor and Allen Distinguished Investigator Nikolai Slavov published a perspective article in Nature Biotechnology “Increasing proteomics throughput” highlighting new mass-spectrometry technologies transcending limitations in the throughput of proteomics and opening the stage for many exciting applications.

Nikolai Slavov

Voices of biotech research

As part of the 25th anniversary of Nature Biotechnology, BioE Assistant Professor and Allen Distinguished Investigator Nikolai Slavov published his future vision in the article “Voices of biotech research” about what he thinks are the most exciting and essential biotechnology opportunities.

professor working in lab

Slavov Named Paul G. Allen Distinguished Investigator for Pioneering Single Cell Proteomics Research

Bioengineering Assistant Professor Nikolai Slavov was recently named a prestigious Allen Distinguished Investigator and was awarded a $1.5 million three-year grant to further his novel research on single cell proteomics. The Paul G. Allen Frontiers Group supports early-stage research with the potential to reinvent entire fields. Slavov is the first from Northeastern to receive the award.

Nikolai Slavov

The single cell proteomics revolution

An editorial in BioanalysisZone highlights research from the Slavov Lab that has led to the rapidly advancing field of single-cell protein analysis by mass-spec.

Nikolai Slavov

Unpicking the Proteome in Single Cells

BioE Assistant Professor Nikolai Slavov’s research into using single-cell mass-spectrometry methods for high-throughput analysis of proteins is featured in the Science article “Unpicking the proteome in single cells.”

Nikolai Slavov

Voices in methods development

As part of the 15th anniversary of Nature Methods, BioE Assistant Professor Nikolai Slavov was featured in the article “Voices in methods development” about what he thinks are the most exciting and essential methodological biology challenges that are poised to be tackled in the near future.

A Dream of Single-Cell Proteomics

BioE Assistant Professor Nikolai Slavov Lab was highlighted in the Nature Methods article A Dream of Single-Cell Proteomics highlighting their research in single-cell proteomics.

Improving Protein Measuring Technology

Bioengineering Assistant Professor Nikolai Slavov has developed a breakthrough method of identifying more than a thousand proteins per cell which could help map the functions of them throughout the body.

Bajpayee and Slavov Receive Sanofi iAwards

BioE Assistant Professors Ambika Bajpayee and Nikolai Slavov were each recipients of a $125K Sanofi iAward, which were created to promote scientific breakthroughs by tapping into the world’s greatest minds through close collaboration with renowned academic institutions.

NIH Highlights Slavov's Innovative Research

The NIH Director’s office highlighted game-changing research on “Pinpointing Plenty of Proteins – in a Single Cell” conducted by BioE Assistant Professor Nikolai Slavov and his team.

A big breakthrough for regenerative medicine?

BioE Assistant Professor Nikolai Slavov has devised a method to identify more than a thousand proteins in an individual cell and estimate their abundance.

Through the Looking Glass of Single Cell Proteomics

Research from BioE Assistant Professor Nikolai Slavov’s lab was featured in Technology Network’s article “Through the Looking Glass of Single Cell Proteomics“

Pioneering single cell proteomics

The article “Transformative Opportunities for Single-Cell Proteomics”, which is research from BioE Assistant Professor Nikolai Slavov’s Laboratory, is featured on the cover of the Journal of Proteome Research.

Northeastern Engineering Hosts First Single Cell Proteomics Conference

The 1st Single Cell Proteomics (SCP) Conference was recently held at Northeastern which focused on demonstrating the feasibility of quantifying thousands of proteins in single cells by mass-spectrometry

Faculty and Staff Awards 2018

Congratulations to all the winners of the faculty and staff awards, and to everyone for their hard work and dedication during the 2017-2018 academic school year.

GenomeWeb Highlights Single Cell Proteomics Method Developed in the Slavov Laboratory

Research pioneered in BioE Assistant Professor Nikolai Slavov’s laboratory on a mass-spec method for quantifying proteins in single cells (SCoPE-MS) was highlighted on GenomeWeb.

Are preprints the future of biology? A survival guide for scientists

BioE Assistant Professor Nikolai Slavov was featured in Science magazine’s article on “Are preprints the future of biology? A survival guide for scientists“

Festival of Genomics highlights research from the Slavov Laboratory

Festival of Genomics interviewed BioE Assistant Professor Nikolai Slavov to find out about the origins and the future of a new method for quantifying thousands of proteins in single human cancer and stem cells that his laboratory developed: What are you working on right now? In terms of technology development, we are evolving our approach to Single Cell ProtEomics […]

How Statistics Weakened mRNA’s Predictive Power

Research from BioE Assistant Professor Nikolai Slavov's laboratory is highlighted in The Scientist in the article entitled "How Statistics Weakened mRNA’s Predictive Power".

GenomeWeb News and Proteomics News highlight research from the Slavov Lab

Recently the Slavov lab developed Single Cell ProtEomics by Mass Spectrometry (SCoPE-MS), and validated its ability to identify distinct human cancer cell types based on their proteomes. They used SCoPE-MS to quantify over a thousand proteins in differentiating mouse embryonic stem cells. The single-cell proteomes enabled them to deconstruct cell populations and infer protein abundance […]

Slavov Receives NIH Director’s New Innovator Award

BioE Assistant Professor Nikolai Slavov was awarded the National Institutes of Health Director's New Innovator Award and a $2.35M grant to study "Ribosome-Mediated Translational Regulation during Stem Cell Differentiation".

FY17 TIER 1 Award Recipients

23 COE faculty and affiliates were recipients of FY17 TIER 1 Interdisciplinary Research Seed Grants for 12 different projects representing over $600K dollars of investment in research.

Research from the Slavov Lab highlighted in a Cell Press Spotlight by Thomas Preiss

BioE Assistant Professor Nikolai Slavov's research was featured in Trends in Biochemical Sciences for "All Ribosomes Are Created Equal. Really?"

Slavov Writes Feature Article in eLIFE

BioE Assistant Professor Nikolai Slavov wrote the feature article in eLIFE about "Making the most of peer review".

A New Direction in Ribosomes

BioE Assistant Professor Nikolai Slavov has shown that cells build different ribosomes that likely not only assemble amino acids into proteins but also regulate protein production.

New Faculty Spotlight: Nikolai Slavov

Nikolai Slavov joins the Bioengineering department in Fall 2015 as an Assistant Professor.