Our long-term research goal is to develop and apply innovative spatial, single cell and optical technologies that will transform our understanding of cellular communication in health and disease and use this insight to develop new treatments.
Design and use of biomaterials for wound healing; antimicrobial/antibiofilm strategies; soft-tissue replacement; polymer condensates; and sustained delivery of therapeutics
Production of valuable pharmaceutical compounds from plant cell cultures, specifically the production of important anti-cancer drug molecules from cell cultures of Catharanthus roseus
Image and signal processing as applied to biophysical data designed to answer fundamental questions about the molecular basis of living systems, and progression of Alzheimer's Disease
We study cell-cell and cell-extracellular matrix interactions in the airway to understand the fundamental mechanisms that regulate airway caliber and why they fail in diseases like asthma.
Developing chemical approaches to track and quantify important RNA processing events and modifications in single cells; DNA: protein interactions that drive differences in gene expression; understanding differences in RNA expression and the impacts on disease and development